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" Every era casts cancer in its own image. "
Siddhartha Mukherjee
Image
Own
Cancer
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" Unlike other diseases, the vulnerability to cancer lies in ourselves. We always thought of disease as exogenous, but research into cancer has turned that idea on its head - as long as we live, grow, age, there will be cancer. "
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" If there's a seminal discovery in oncology in the last 20 years, it's that idea that cancer genes are often mutated versions of normal genes. "
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" I think when we use 'stress', we are often using a kind of dummy word to try to fit many different things into one big category. "
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" Cell culture is a little like gardening. You sit and you look at cells, and then you see something and say, 'You know, that doesn't look right'. "
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" When you immerse yourself in medicine you realise that hope is not absolute. It's not that simple. "
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" Postwar U.S. was the world's leader in science and technology. The investment in science research was staggering. "
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" I began wondering, can one really write a biography of an illness? But I found myself thinking of cancer as this character that has lived for 4,000 years, and I wanted to know what was its birth, what is its mind, its personality, its psyche? "
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" Most discoveries even today are a combination of serendipity and of searching. "
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Today
" Each of us knows a few or several young people whose lives have been devastated by cancer. I don't mean to be nihilistic about it, but it is very much an active killer of people now. "
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" I am a scientist and I am a physician. So I write papers. "
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" I left Delhi in 1989 and remember very little of how life used to be then. Increasingly, in my recent visits to Delhi, I've started to realize that the city has become intellectually very lively. It makes me want to discover the city over and over again. "
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" Writing anything as an expert is really poisonous to the writing process, because you lose the quality of discovery. "
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" Most days, I go home and I feel rejuvenated. I feel ebullient. "
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Days
Feel
" Pharmacology is benefited by the prepared mind. You need to know what you are looking for. "
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Mind
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" We know cancer is caused ultimately via a link between the environment and genes. There are genes inside cells that tell cells to grow and the same genes tell cells to stop growing. When you deregulate these genes, you unleash cancer. Now, what disrupts these genes? Mutations. "
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" My memory of my household is of one immersed in books and music. I have a very intimate relationship with Bengali literature, particularly Tagore, and my interest besides reading then was music. "
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Relationship
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" Probably the most important reason we are seeing more cancers than before is because the population is ageing overall. And cancer is an age-related disease. "
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" A breast cancer might turn out to have a close resemblance to a gastric cancer. And this kind of reorganization of cancer in terms of its internal genetic anatomy has really changed the way we treat and approach cancer in general. "
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" One day, I had a patient who was going through chemotherapy who came to me and said, 'I'm going to go on with what I'm doing, but I need you to tell me what it is that I'm fighting.' "
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" There is an enormous amount of options that a physician can provide today, right down from curing patients, treating patients, or providing patients with psychic solace or pain relief. So, in fact, the gamut of medical intervention is enormous. "
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" There's a rising cancer trend and, as I said, one of the major contributors is the overall ageing of the population - we aren't dying of other things, so we're dying of cancer. "
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" Mary Lasker was an entrepreneur; she was a socialite. She was kind of a legendary networker. She became interested in saying, 'Well, you know, if these diseases don't have political support we'll never conquer them.' And she made, really, cancer her special cause. "
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Saying
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" It turns out that the very genes that turn on in cancer cells perform vital functions in normal cells. In other words, the very genes that allow our embryos to grow or our brains to grow, our bodies to grow, if you mutate them, if you distort them, then you unleash cancer. "
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Cells
" I once set myself a deadline: half a chapter a week, 20 minutes a day. The thought froze me instantly, like literary Botox. I returned to my non-schedule: sleeping, writing 20 minutes, and then back to sleep. Breakfast in bed, with juice congealing on the sill: pages and pages began to pour out again. "
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Sleep
Day
Breakfast
" I think the cardinal rule of learning to write is learning to read first. I learned to write by learning to read. "
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First
" Cancer has enormous diversity and behaves differently: it's highly mutable, the evolutionary principles are very complicated and often its capacity to be constantly mystifying comes as a big challenge. "
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" Cancer is not just a dividing cell. It's a complex disease: It invades, it metastasizes, it evades the immune system. "
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" The gene that enables birds to learn songs can become cancer-causing. There is no normal physiological process that can't be bastardized by the disease. "
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" There is a duality in recognising what an incredible disease it is - in terms of its origin, that it emerges out of a normal cell. It's a reminder of what a wonderful thing a normal cell is. In a very cold, scientific sense, I think a cancer cell is a kind of biological marvel. "
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" The history is important because science is a discipline deeply immersed in history. In other words, every time you perform an experiment in science or in medicine, what you're actually doing is you're answering someone, answering a question raised by someone in the past. "
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History
Science
Past