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" After doing One Fine Day and playing a pediatrician on ER, I'll never have kids. I'm going to have a vasectomy. "

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" But I'm kind of comfortable with getting older because it's better than the other option, which is being dead. So I'll take getting older. "

" I go on YouTube when somebody says to look something up. "

" You get better as an actor over time if you're growing. Like singers. "

" There is something very unsettling about being with someone when they die. People say it's peaceful. It's not peaceful. It's the most personal thing you can do, is die, and you feel almost like you're invading someone's most personal moment by being there. "

" Yes, I slouch. My mother tells me that. "

" You make a lot of films, do you? You make a lot of films yourself? Yeah, I'd like to see you make a film first before you get to talk about it. What a jerk. "

" I don't believe in happy endings, but I do believe in happy travels, because ultimately, you die at a very young age, or you live long enough to watch your friends die. It's a mean thing, life. "

" I'm the old-fashioned type who prefers to meet a woman in a more normal setting. I don't like to feel that I'm being hunted down. I've always liked to do my own hunting when it comes to meeting women. "

" America can't beat anyone anymore. "

" I don't know if winning at any cost is wrong or not. There are times I've thought that the end justified the means. "

" I'm really white trash. "

" I can't give you 150 takes. I can't even give you 30 different ways of doing it! I don't have the talent or the range for it. "

" I do know something about the news world. I was sitting on the floors of newsrooms since I was seven years old, and I've been around them my whole life. I understand that someone looks at a story with famous people in it, and you want to put it out. "

" For me, the definition of a patriot is someone who is willing to constantly question the government; that's what separates us from other countries. "

" It's possible for me to make a bad movie out of a good script, but I can't make a good movie from a bad script. "

" I've been lucky enough to do a few films that will last longer than an opening weekend and those films are the ones I'm proud of. "

" Growing old on screen is not for the faint of heart. "

" The people I've respected most in the industry over the years - Paul Newman, for instance. I just loved the way he handled growing old on-screen. It's understanding that you're now basically a character actor. Which is fine, but you have to pay attention to it. "

" I use my film-making to work through my deep questions and my deep problems. I think I could watch each film and tell you exactly which part of my psyche I'm trying to work out. "

" In doing the screenplay for 'Good Night, and Good Luck,' the most important thing for me was to constantly go back to wherever the opposition would argue. So I had to keep reading all the books and articles about why McCarthy is such a good guy. "

" You have only a short period of time in your life to make your mark, and I'm there now. "

" I'm only two years older than Brad Pitt, but I look a lot older, which used to greatly frustrate me. It doesn't anymore. I don't have to fit into that category and get trounced by Tom Cruise and Brad. "

" I've had some success at writing and directing, and I like it. It's infinitely more creative than just acting, and I have things I want to say and do. "

" The problem is, we elected a manager and we need a leader. Let's face it: Bush is just dim. "

" I'm not out trying to prove anything. I'm sort of finished with that, so I get to play in other sandboxes and try and figure out what I like and I'm interested in. "

" Failures are infinitely more instructive than successes. "

" I think you should automatically donate your organs because that would turn the balance of organ donation in a huge way. I would donate whatever anybody would take, and I'd probably do the cremation bit. "

" I'm a Method actor. I spent years training for the drinking and carousing I had to do in this film. "

" I've been my most happy and my most unhappy in relationships. I have family and friends and people I care very much about. I've got a really, really, really good life. "

" 'Ides of March' I did for scale - scale as a director, scale as an actor, scale as a writer. "