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" As cliched as it sounds, if you have an original voice and an original idea, then no matter what anybody says, you have to find a way to tell that story. "

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" The year that 'Lost' started and premiered was, without a doubt, the most miserable year of my life. The level of despair and anguish that I was feeling; I was clinically depressed, and anyone that you talked to who knew me at the time will tell you that. "

" A lot of writers whom I love, admire and call friends share this feeling, which is this fundamental idea that we're frauds. That we will be pushed out on to the stage, and it will be revealed that the emperor has no clothes. "

" The fundamental law of nature is to not know too much about yourself. "

" Essentially, there's no scientific evidence whatsoever that could ever be presented to me that would wipe out my fundamental spiritual beliefs. "

" We all look at ourselves in the mirror and think, 'Am I good?' "

" I saw myself as a teacher's pet but with a little of Ed Haskell mixed in. I was the teacher's pet, but that didn't mean that I was trying to pull one over. "

" I would say that my fatal flaw, as a human being, is that I need people to like me, and if they don't like me, I will obsess over it - and try to change my personality until they like me - even if they don't like me for reasons that have nothing to do with me, and even if they're strangers. "

" I have found, unfortunately, that if I take on too many projects at one time, there is a higher probability of those projects sucking. "

" I believe that this idea of story or myth or this thing that Joseph Campbell writes about is sort of an inter-connective spiritual force - like The Force in 'Star Wars' - where it doesn't matter where you were raised, or what your background is, there are certain elements of story that totally appeal to you. "

" I feel like great TED Talks are ones that are a little bit subject to interpretation, that do provoke further conversation - and potentially controversy. "

" My gravestone will say, 'Here Lies Damon Lindelof - Or Does He?' "

" I always remember liking school. "

" My father - until the day that my dad died - didn't know how many points you scored in a touchdown. He could say there were nine innings in baseball, but no intricacies of the sport. "

" I look at myself more as a storyteller than a screenwriter, as pretentious as that may sound, but that's what really attracts me to TED Talks. For me, the really effective ones are being presented by expert storytellers. "

" When someone says something that really hurts me, I have to retweet it to let it go. "

" I don't think anybody wants to see a dour 'Star Trek' movie. "

" The interpretive element of 'Lost' - the fact that you immediately need, as soon as the episode is over, to seek out a community of people to express your own thoughts about it, understand what they thought about it and form an opinion - that's the bread and butter of the show. "

" In really, really good science fiction, the line between the science and the fiction is blurry. "

" I remember what it was like to be doing 'Lost' and how creatively immersive it was. I just couldn't really engage on anything else, other than 'Lost;' I was just thinking about it all the time, and then there was just the pure workload, the 70- or 80-hour weeks. "

" I love collaborating with different people. "

Different People

" All great sci-fi is: Be careful what you wish for. "

" I'm not sitting around thinking of ideas for TV shows. "

" Michael Arndt, that guy - you're just supposed to say nice things about other writers, but I worship Michael Arndt. "

" I love finding new creative partnerships but then continuing the partnerships I'm already in. "