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" As I look back on the last few decades of my life, I am struck by the good fortune that came my way. "

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" So I applied to medical school and received a scholarship at Washington University in St. Louis. Washington University turned out to be a lucky choice. The faculty was scholarly and dedicated and accessible to students. "

" The glimpses of human strength and frailty that a physician sees are with me still. "

" And of course, identifying all human genes and proteins will have great medical significance. "

" I also found out that I liked biochemical research and that I could do it. "

" My parents came to the United States in the early years of this century as part of a wave of Russian Jewish immigrants seeking freedom and opportunity in the New World. "

" At every stage of my career I have had interesting and cordial colleagues, some of whom are close friends. "

" First of all, many human diseases are influenced by, if not caused by mutations in genes. "

" Small science, which includes most research in the life sciences all over the world, is science directed usually by an individual senior scientist and a small team of junior associates, perhaps three, ten, fifteen, something in that order. "

" People are not the only interesting organism on earth. From the point of view of scientific or commercial value, there are lots of interesting organisms. "