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" At the suggestion of Professor Itaru Watanabe, and with his help, I left Japan at the age of twenty-three to pursue graduate study at the University of California at San Diego. "
Susumu Tonegawa
San Diego
Study
California
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" Independent of what is happening around you in the outside world, humans constantly have internal activity in the brain. "
Susumu Tonegawa
You
Brain
Independent
" I decided to pursue graduate study in molecular biology and was accepted by Professor Itaru Watanabe's laboratory at the Institute for Virus Research at the University of Kyoto, one of a few laboratories in Japan where U.S.-trained molecular biologists were actively engaged in research. "
Susumu Tonegawa
Research
Biology
University
" It doesn't matter whether it is chemistry or immunology or neuroscience: I just do research on what I find interesting. "
Susumu Tonegawa
Find
Interesting
Chemistry
" My scientific career has developed on three continents: Asia, Europe and North America. "
Susumu Tonegawa
Europe
Asia
America
" The brain is probably the most mysterious subject there is. "
Susumu Tonegawa
Mysterious
Most
Subject
" Although we often discussed the idea of research on the nature of antigen recognition by T cells in the laboratory in the late Seventies while I was still in Basel, the real work did not start until the early Eighties in my new laboratory at M.I.T. "
Susumu Tonegawa
Start
Nature
Early
" I became fascinated by the then-blossoming science of molecular biology when, in my senior year, I happened to read the papers by Francois Jacob and Jacques Monod on the operon theory. "
Susumu Tonegawa
Science
Senior Year
Biology
" In 1981, after ten years in Basel, I returned to the United States to continue my research on the immune system at the Center for Cancer Research of the Massachusetts Institute of Technology where Director Salvador E. Luria provided me with an excellent laboratory. "
Susumu Tonegawa
Me
Technology
System
" My father was an engineer working for a textile company that had several factories scattered in rural towns in the southern part of Japan. "
Susumu Tonegawa
Working
Company
Engineer
" We found out that, contrary to what many people thought, in the immune system, genes can change during the life cycle of the individual. "
Susumu Tonegawa
People
Change
Thought
" Immunologists agreed that an individual vertebrate synthesizes many millions of structurally different forms of antibody molecules even before it encounters an antigen. "
Susumu Tonegawa
Before
Even
Individual
" In the early Seventies, the technology for purifying a specific eukaryotic mRNA was just becoming available. "
Susumu Tonegawa
Seventies
Early
Just
" Humans are very imaginative animals. "
Susumu Tonegawa
Humans
Animals
Very
" When General Motors builds a car, they want to meet the specific needs of many customers. But if they custom-make each car, then it will not be economical. "
Susumu Tonegawa
Will
Customers
Meet
" Even under normal conditions, how we can distinguish various events, various experiences, and be able to reproduce it later is, of course, a very interesting question and, I think, one that we face in day to day life. "
Susumu Tonegawa
Think
Face
Interesting
" The brain is hugely complicated, and because it is so complicated, it requires multidisciplinary research. "
Susumu Tonegawa
Research
Because
Complicated
" Recalling a memory is not like playing a tape recorder. It's a creative process. "
Susumu Tonegawa
Process
Playing
Creative
" I commuted to the prestigious Hibiya High School from my uncle's home in Tokyo. During the high school years, I developed an interest in chemistry, so upon graduation, I chose to take an entrance examination for the Department of Chemistry of the University of Kyoto, the old capital of Japan. "
Susumu Tonegawa
Home
School
Graduation
" I see myself as a scientist who is interested in what's going on inside of us. "
Susumu Tonegawa
Inside
I See
Going
" After I arrived in Basel, I initially attempted to continue the project of my days in Dulbecco's laboratory, namely, the transcriptional control of the simian virus 40 genes. "
Susumu Tonegawa
Project
Laboratory
Control