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" I get really excited about specific therapies, personalized therapies. Like, let's say, taking a piece of someone's tumor and testing a bunch of treatments in a lab and being able to come up with the right therapy for that specific patient. "

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" Every crazy fad from the 1800s comes back or they never go away. It's like fashion, like everything's already been invented, and somebody stumbles onto it and people will always, always be looking for an answer for some vague illness they can't get a diagnosis for. "

Mary Roach

Crazy

Fashion

Looking

" I write with a sense of my future readers being ever on the verge of setting down the book and pronouncing it a bore. Fear and insecurity are great motivators. "

" People don't appreciate their intestines until something goes wrong. But I always hope that people gain a little appreciation for their guts. "

" I could have had a session of defecography, which is a diagnostic test in which X-rays are taken to assess anatomical problems occurring during the process of defecation. I gave it the briefest of thoughts before recognizing that this is beyond the pale - even for me. "

Mary Roach

Test

Thoughts

" I rarely listen to music while writing. I wish I could, but it distracts me. "

" If you could really guarantee that the money would be spent on something more worthwhile, I'd say, absolutely, scrap the space program, but it never works that way. "

" I don't write on topics that require a lot of urgency. But in 'Stiff,' I wanted to change people's hearts about organ donation. Whenever I get a chance, I try to talk about that. "

" I used to do my best thinking while staring out airplane windows. The seat-back video system put a stop to that. Now I sit and watch old' Friends' and 'Everybody Loves Raymond' episodes. Walking is good, but here again, technology has interfered. I like to listen to iTunes while I walk home. I guess I don't think anymore. "

" I think by and large, humans prefer to think of themselves as minds from the neck up. We don't really like to think of ourselves as another animal, another digesting, excreting, mating, snoring, sleeping kind of sack of guts. I don't think we like that. I think we'd rather not be reminded of it. "

" When you buy my books, you kind of know what you're in for. It's kind of self-selecting. If you have a delicate sensibility, and you're easily grossed out, you probably will never read one of my books. "

" There are fast chewers and slow chewers, long chewers and short chewers, right-chewing people and left-chewing people. Some of us chew straight up and down, and others chew side-to-side, like cows. Your oral processing habits are a physiological fingerprint. "

" Picking my topics is sort of a process of elimination for me. Most things don't work for me. I like to cover science and unexpected things happening in labs. Also, theoretical research doesn't work for my style. I need scenes and interactions. Then, humor. I'm having the most fun when I can have fun with my work. "

" People are surprisingly off put just by saliva, the substance that you carry around in your mouth. You swallow it. You have no objection to it. But then it leaves your body, and you're just revolted. So it - that - just that right there to me is a fascinating thing. "

Mary Roach

Body

Mouth

" Spacewalking is a little like rock climbing in that everything, including and especially oneself, must be tethered or docked at all times. If you forget to tether a tool, it's gone. Ditto yourself. "

" Most of the people who are engaged in the subjects that I look into are pretty interesting. Whether its sex researchers or someone who's devoted their career to saliva or somebody who does research with cadavers, there's an inherent fascination in the subject matter of their work. "

" My books are not really books; they're endless chains of distraction shoved inside a cover. Many of them begin at the search box of Pub Med, an Internet database of medical journal articles. "

Mary Roach

Internet

Medical

" I have a nice little office, with a nice little window in it, but I do basically spend huge amounts of time in what you could consider solitary confinement. "

" Day by day, I'm kind of a bore. "

" Follow your instincts. Do the kind of writing you love to do and do best. 'Stiff' was an oddball book - I mean, a funny book about cadavers? - and I worried that it would be too unconventional. In the end, that's what has made it a success, I think. "

" I don't know of many people who've done sex research with an eye toward people saying sex is bad for you, except for the promiscuity and cervical cancer link - which is actually a valid discovery. "

" When I'm done with a book, I always give it to someone with expertise in the topic and tell them to flag all of my stupid mistakes. "

" I spend a lot of my time on the phone, pestering people. 'What's new in your lab? Can I come visit your lab? When can I come visit your lab?' I'm basically a professional pesterer. "

" I had a bike accident a few years ago, and I went to the emergency room, and I had to have a gash sewn up. And I am the kind of person that I was sitting up fascinated, watching, to the extent that the doctor said, 'Do you want to do a couple of stitches? You seem to be very interested.' "

" There are three kinds of people in this world: 1) People who make lists, 2) People who don't make lists, and 3) People who carve tiny Nativity scenes out of pecan hulls. I'm sorry, there isn't really a third category; it's just that a workable list needs a minimum of three items, I feel. "

" Eighty percent of flavor comes from your nose, including a set of internal nostrils. When you chew food and hold it in your mouth, the gases that are released goes into these nostrils. People who wolf their food are missing some of the flavor. "

" I've been writing full-time since about 1984 - mostly magazine features and columns. "

" A space station is a rangy monstrosity, a giant erector set built by a madman. "

" We exist in this weirdly schizo culture, where sex is everywhere in the media, and yet, at the same time, you don't sit down and have a conversation about what you did in bed last night with your friends. Despite the ubiquity of sex, it's still a taboo when it comes to day-to-day conversation. "

" To me, death is dark, pain, grief. "

" Dead people never seem to address the obvious - the things you'd think they'd be bursting to talk about, and the things all of us not-yet-dead are madly curious about. Such as: 'Hey, where are you now? What do you do all day? What's it feel like being dead? Can you see me? Even when I'm on the toilet? Would you cut that out?' "

Mary Roach

Day

You