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" I like the nexus of Bollywood and Hollywood. I'm actually shocked that there isn't more of a meld between our two industries. "

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" Sobriety was the greatest gift I ever gave myself. I don't put it on a platform. I don't campaign about it. It's just something that works for me. It enabled me to really connect with another human being - my wife, Sheryl - which I was never able to do before. "

" I couldn't have gotten sober without rehab because I needed the science. "

" I'll never forget one of those things that my father said to me. My father said: 'You know what? We have had so many amazingly positive experiences that we would have never had because you're famous. We can stand to have a couple negatives ones, too.' "

" Let me just say this - sometimes being a trailblazer is highly overrated. "

" I liked being a teenager, but I would not go back for all the tea in China. "

" I feel pressures to stay relevant. To stay interesting and interested. To stay at the top of my game and expand. "

" I started out being a really, really liberal Democrat. "

" By making more people aware of lymphoma, Worldwide Lymphoma Awareness Day hopes to save lives by increasing early diagnosis and suitable treatment. "

" It's a little bit of a 'if you can't beat 'em - join 'em' mentality for me when I think about Twitter. "

" Before you could actually have face-lifts, they would pull your skin around the back of your head with rubber bands, where they would tape it. And then you'd have to wear a wig over it to hide the rubber bands. It was not the most comfortable. "

" I've come to really like Twitter. You really do get to see what I'm about, and I like sharing with my fans. "

" I've been lucky enough in 'The West Wing' and 'Brothers & Sisters' to talk about the issues that are important to me with none of the awful mud-slinging or public scrutiny you have in politics. "

" The '80s were about trying to establish myself as an actor with a career. And being a teenager enjoying the fruits of being successful with lots of what I think is appropriate for that age. "

" I didn't go to Ivy League schools. I dropped out of college to go into movies. "

" I've said before that the common perception that all good actors should be good liars is exactly the opposite; only bad actors lie when they act. "

" I'm no genius, but I'm real smart in one area - I picked the right mate. "

" I love anything by Joan Didion. Incidentally, she was one of the local moms when I was growing up in Point Dume. She always reminded me a little bit of my mother, so I feel a great affinity. I love the precision of Didion's writing. There's a construction and a craftsmanship to her sentences that's imbued with so much emotion. "

" When you're writing personal stories, you have to be totally uncompromising - to the extent that you can be - about yourself. I know that if I am uber-uncompromising with myself, that gives me some latitude to write about others. "

" Oh my God, I love rehab! I highly recommend it. "

" I had had some successes in the '90s, always made money, but the truth was I was like a man pushing a boulder up a hill. A huge, heavy, difficult boulder made up of some career mistakes, projects that didn't meet expectations, and twenty years of being a known quantity. "

" Like most guys, I don't come to beauty regimes naturally. I'm dragged kicking and screaming by the best in the world. "

" I've had years of psychiatry, and I ask about every six months - it's sort of like getting your oil checked - I ask, 'I'm not an actual narcissist, am I?' The learned men of psychiatry assure me that I meet none of the medical criteria. "

" My life and the lives of many across the world have been deeply affected by lymphoma. "

" I've been on TV a long time, and I've never had a catch phrase. "

" I look at it like this: that if Shakespeare were alive today, he would have written two or three plays about the Kennedy family, and actors would traditionally play JFK like they Hamlet or King Lear. They just would. I mean, people have played JFK, and they'll play him long after I have. "

" The first private space of my own wasn't a dorm room; it was a hotel room in Tulsa, Oklahoma. "

" For sure, without question, the writing is better on TV pound for pound than movies because the businesses have changed so much. So all the great writers would rather work for TV, and they do. "

" The first shooter video game stuff which - look, admittedly, I missed that generationally, so it's not a thing for me. I've never played them. I don't really get it. My kids do. "

" My deep dark secret is that I was a nerd in school. I liked the theater. I liked to study. I wasn't very good at sports. "

" I'm a true centrist: my beliefs put me in the middle... You know what happens to people who drive in the middle of the road? They get run over. "