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" I think all scientists are like detectives. We are most happy when we find something that doesn't fit our expectations. "

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" If I see something that seems out of sync with what's already known, the first thing I do is try to find out what's wrong with the data. Once you've done that, and it still seems wrong, that's when things get interesting. It means you've found something new to understand. "

" The thing about telescopes is that the mirror is the main component. Once that's built, you don't need to build new ones; you just need to swap out the instruments. There's nothing wrong with Hubble's mirror. "

" The Internet has made communication far more rapid. If there is a discovery, instantly around the world, anyone can confirm it. "

" Weather forecast for Jupiter's South Equatorial Belt: cloudy with a chance of ammonia. "

" We don't use Hubble to stare at Jupiter unless there's a special event or some special reason. "

" We need to be very thoughtful about how we propose to spend the money that NASA does have for space exploration. And we need to be clear that there's the human spaceflight part of NASA, and there's the science space part of NASA, and there's also aeronautics. Those are all very different things that NASA does. "

" We really have only been observing Neptune with big telescopes since shortly before 1989. "

" You make sure you broaden yourself and have a good solid background in many different things. That's what you need to be a good scientist. "

" Most people have already seen a cosmic collision. If you've seen a shooting star ever, you've seen a cosmic collision, because a shooting star is not a star. It's a tiny dust or pea sized fragment of an asteroid or a comet hitting our atmosphere and burning up as it hits in, as it comes in. "

" Whatever I was going into, whether it was going to be chorus or history or astronomy or whatever, do it right. Be a professional. Don't just do a half baked job. Do everything correctly. Get down. Learn the details of what you're going to do. "

" Together, NASA and Hubble are opening new vistas on the universe. "

" Technological prescience in science fiction usually requires an author with luck. Societal prescience requires a poet. "

" I don't think I could advocate for increasing NASA's budget by a factor of two or ten, because I want us to have good roads in our country. I want us to have good education in our country. And NASA's budget is part of a discretionary budget, and we can't make that bigger without taking away other things. "

" When I was in college, I didn't like physics a lot, and I really wasn't very good at physics. And there were a lot of people around me who were really good at physics: I mean, scary good at physics. And they weren't much help to me, because I would say, 'How do you do this?' They'd say, 'Well, the answer's obvious.' "

" We need people pushing the boundaries. Exploration is what we, as humans, do. "

" We live inside the atmosphere of an active star. "

" Being insignificant statistically doesn't mean it's right or wrong. It just means you don't have enough data to show yes or no. "

" Every observation that we make, every mission that we send to various places in the solar system is just taking us one step further to finding that truly habitable environment, a water-rich environment. "

" If there were creatures on Uranus - and I don't think there are - seasonal affective disorder would be a lifetime thing. "

" Hubble made my career. "

" The Hubble Telescope can see the farthest galaxies. The Webb Telescope will see the farthest stars. "

" When I first heard that a comet was going to hit Jupiter, my reaction was, 'Eh. So what? Jupiter's huge. Comets are small. And so when I saw the first impact site and it was huge and dark, I was flabbergasted. "

" It's clear that the only thing that is inhibiting us from doing further human exploration of space is money and the will to do it. "

" There's this myth that science is hard. But everything is hard. "

" Ultimately, life is a chemical interaction. "

" There should be a water table on Mars. "

" Scientists normally like to do experiments. You know, they like to mix this with that and see what happens. They like to take this thing and poke it and see how it reacts. In astronomy, we can't do that. The stars, the planets, the galaxies, are so far away that we just look at them, and we have to learn things by looking at them. "

" Even after years of observing, a new picture of Uranus from Keck Observatory can stop me in my tracks and make me say, 'Wow!' "

" It's very clear that global climate change is occurring on earth, but it's also been very clear that that has always happened on earth. We've always had a changing climate on earth. We all know about ice ages. We know when our continent was covered with ice sheets. We know glaciers come and they go. It puzzles me that people forget that. "

" The whole Hubble program has just been a fabulous testament to the NASA science community and the NASA astronaut community. "