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" In 'Plutarch,' her voice begins to come out; there are actual 2,000-year-old quotes from Cleopatra, and they are sly and saucy. "

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" I wouldn't dare to speculate as to Cleopatra's falling in love. Her relationships are too convenient for that. "

Falling In Love

" I went out to the desert where Cleopatra camped out with her mercenary army. It's a desolate outpost. Nothing has changed since her day. You realize how far she had to travel. Not only is it a good 150 miles against the current, you can't take a ship. "

" I think with every book you realize you are partway through and there is something really elementary that you should have researched. "

" The biographer has two lives: The one she leads, and the one she ultimately understands. "

" I once interviewed David Herbert Donald, the Lincoln historian, and we talked about how one deals with the secondary sources and the previous biographies. He said something which kept coming back to me as I worked on Cleopatra, which was: 'There's no further new material; there are only new questions.' "

" For the several thousands of years before they became firefighters and physicians, women were sirens, enchantresses, snares. At times it seems as if female powerlessness is male self-preservation in disguise. And for millennia, this has made for a zero-sum game: A woman's intelligence was a man's deception. "

" You ever try to leave New York? I did once. I lasted about a year. "

" The interesting thing about Cleopatra is that she is such a shape-shifter. I mean through history we've all molded her to our times and our places. So there's room for a movie for her, but I don't think it will hew to the book. "

" I checked to see if there'd been a really good book published in the last few decades. Then I started with what Cleopatra would have read, asking myself, 'What can we know about her education?' It turns out to be a very great deal, and bizarrely, no one had written about that before. "

" Reality does not easily give up meaning; it's the biographer's job to clobber it into submission. You're meant not only to tame it but to extract substance, to identify cause and axiomatic effect. You subsist on the tactical omissions, the hollow words, the oddly unconnected dots. "

" Cleopatra was on a political mission to save her country and her power, but what we remember about her are these two famed seductions, which are a matter of politics, not a matter of love. "

" Nonfiction writers are the packhorses of literature. We're meant to carry the story. If we can make it up and down the mountain by a reliable if not scenic route, we have delivered. Technique is optional. "

" The desk thing is a problem for me. The ideal one would be vast and perfectly clear. Yet the bane of the biographical existence is paper; if you're 'an artist under oath' you're writing from a mountain of documentation. "

" I have three children, each of whom is having an idyllic childhood, probably because I have been at the office the entire time. "

" You have to scuba dive in the Alexandrian harbor if you want to see what remains of the lighthouse of Cleopatra's day, and the water in the Alexandrian harbor is not really something you want to come into contact with. "

" Cleopatra had one great advantage. She lived at a time when female sovereigns were not anomalies. And when women enjoyed rights they would not again enjoy for another 2,000 years. You could call them early feminists, if I may use a dirty word. "

" Certainly, I am writing as a 21st-century woman, so I am much more inclined to view her as a three-dimensional woman. I think we keep coming up with this stubborn problem of a woman being judged by her appearance rather than her accomplishments. We are much more inclined to ask: was Cleopatra beautiful? "

" I can't write a line without music - it provides just the right amount of distraction to keep me focused. Clearly, I still miss the noisy roommates. "

" For a few thousand years, women had no history. Marriage was our calling, and meekness our virtue. Over the last century, in stuttering succession, we have gained a voice, a vote, a room, a playing field of our own. Decorously or defiantly, we now approach what surely qualifies as the final frontier. "

" How does a woman in authority convey that authority? Is it possible for a woman to rule without sounding shrill? Is it possible for a woman to manage without manipulating? All of these things seem to me to be very much at the fore today, and were no less the case 2,000 years ago. "

" In an ideal world, the perfect biographical subject would have been the star of his penmanship class at grade school - and would thereafter write an English that positively sings. "

" We're talking about, essentially, the Roman historians, who wrote Cleopatra into the story mostly so that they could talk about the rise of Rome. And that is one of the problems, of course, in recounting her life. She's only ever apparent to us when there is a Roman in the room, or when her story intersects with the rise of Rome. "

" For thousands of years, men have written history, so it seems to me that most of what we've read is from the male point of view. "

" When finally I mustered the courage to tell a novelist friend that I was talking to editors about a biography, her reply was, 'Oh, that's okay. That's not a real book.' "

" A woman can never be too rich or too thin, but until very, very recently, she could be too powerful, for which - if she wasn't smart enough to camouflage herself - she generally paid the price. "

" Have you ever been married? Had that thing of someone calling you by a name not your own? It's unsettling. It's like a fictitious person. "

" No one in the modern world controls the wealth or territory that Cleopatra did. "

" From every ancient source, we have testimony to Cleopatra's irresistible charm, as Plutarch has it, to her ability to speak many languages including, as he puts it, the language of flattery and essentially, to be able to turn people to her will - really a great political genius, in that respect. "

" I'm a sucker for lost worlds. I was nostalgic even as a child. I was happiest in my hometown library in Adams, Mass., where nothing seemed to change. "

" Life-writing calls for any number of dubious gifts: A touch of O.C.D., a lack of imagination, a large desk, neutrality of Swiss proportions, tactlessness, a high tolerance for archival dust. Most of all it calls for an act of displacement. 'To find your subject, you must in some sense lose yourself along the way,' is Richard Holmes's version. "