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" It's interesting to play a real-life person who has already been a character on 'Saturday Night Live.' "

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" Like anything else, acting can become boring - a chore, really - if there isn't any challenge. And I like taking challenges. Just when people think they have me figured out, I like to surprise them. "

" For me, the key is years of the blessed filmmakers I've worked with giving me permission to be bold and jump off cliffs and to be boundaryless. I would put David Lynch at the top of that list. "

" I care a lot about big food and everyone's right to healthy, nutritious food and what's caused obesity in America and obesity in children in America. "

" I've worked with David Lynch since I was 17, and working with him is home and family; being around Alexander Payne is home and family, Jonathan Demme. There are directors... Robert Altman, Paul Thomas Anderson... They are directors where I create homes. "

" My daughter wants to do yoga with me and wants to be in the theater thing, and I can't tell her, 'Don't be an actress.' My son loves guitar and loves to be in a band and wants his iTunes downloaded with all this old-school hip-hop so he understands where hip-hop came from. "

" David Lynch is like that - every sound, every detail to the end of making the film, he never gives up. It has to be perfect. "

" That's life - to turn each other on, to feel good, to feel in love. "

" I made a commitment to myself; that I wanted to be an actress, and I wanted to do films that make a difference. It has to move people. "

" Every role is a new form of surrender. "

" I like to play people who are deeply flawed, and I want to find the good nature in them. I even try to be kind to myself when I've made big mistakes. "

" I think people do their bravest work when given an elusive canvas. That would be seemingly the weirdest, but also the most wonderful. "

" A lot of people have asked whether acting is in my genes. I don't know if anyone is born to act. And it certainly wasn't pushed on me. It was something I wanted to do. "

" Sometimes my family got me in the door. Somebody would say, 'Bruce Dern's daughter - sure I'd like to meet her.' It was a point of interest. But after five minutes of talking about my father, I still had to read for the part. "

" I will be working with David Lynch when I'm 80. "

" I'm lucky enough that directors sometimes seek me out for little projects that people don't even know about, that just surface later on. "

" We like our archetypes and heroes to be what they are at face value. And life doesn't work out like that. "

" I have a very wonderfully, bizarrely amazing relationship with my mother in that we've been through a myriad of emotions because we've acted together and played all these different kinds of mother-daughters. "

" I've seen 3-D movies where it seems a little crude or too in-your-face. "

" I resent ever being stereotyped. "

" Something that I've cared about deeply my whole career is getting to work with filmmakers and inventors of stories that are hysterical because they are just so painfully true. "

" You'll be offered the 'lead' in this new hot film with such-and-such A-list director, 'a fabulous part' - a fabulous part? A fabulous part is a character with a soul, who starts here and goes to there, you know? There aren't many of those. "

" I don't want to mess with my face. So I'm becoming fluent in French so I can go to France and make French films when I'm 60. "

" I can't say 'I'm proud to say' - because it's not a choice for many Americans - but I can say I'm fortunate enough to not be raising my kids on McDonald's. "

" As an actor, you're not kind of thinking about your own work or watching the movie for the first time. "

" I love Clint Eastwood, and I wish to work with him again. He's completely irreverent about everything, including his own beautiful work. "

" Being an actress my whole life, it feels so good to have a clean face when I'm off, so I'm not a big makeup wearer. "

" I was raised Catholic, and my grandmother taught me to stay. As a teenager, I thought if you went on a date, you should stay for a couple of years. I didn't realize that if he wasn't your cup of tea, you got to leave. "

" There are a lot more female writers wanting to direct their own material and hopefully will be given the opportunity. "

" For me, the greatest good fortune I have being raised by actors is I came in knowing that a career is the ebb and flow. "

" You don't always get to work as much as you like, because I'm waiting to find things that I care about. Sometimes that's frustrating. "