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" Mammalian cells of all types disgorge prostaglandins at the slightest provocation, but the tissue content of prostaglandins is very low compared with the release. "
John Vane
Low
Tissue
Release
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" Ways have to be found to maintain university research untramelled by requirements of forecasting application or usefulness. "
John Vane
Ways
Found
Research
" Fundamental discoveries can and should be made in industry or academies, but to carry that knowledge forward and to develop a new drug to the market has to depend on the resources of industry. "
John Vane
New
Carry
Depend
" We lived in a suburb of Birmingham where I attended the local state school from the age of five. I then went on to King Edward VI High School in Edgbaston, Birmingham. "
John Vane
High
High School
Age
" At the age of 12, my parents gave me a chemistry set for Christmas, and experimentation soon became a consuming passion in my life. "
John Vane
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Me
Life
" Physiology has spawned many biological sciences, amongst them my own field of pharmacology. "
John Vane
Many
Field
Biological
" Most uses of bioassay involving smooth muscle demand high sensitivity and specificity. "
John Vane
Smooth
High
Demand
" After qualifying for a B.Sc. in pharmacology, I spent a few months in Sheffield University as a research worker in the pharmacology department but then went back to Oxford to the Nuffield Institute for Medical Research in order to study for a D. Phil. with Dr. Geoffrey Dawes. "
John Vane
Back
Medical
Order
" At first, I was able to use a Bunsen burner attached to my mother's gas stove, but the use of the kitchen as a laboratory came to an abrupt end when a minor explosion involving hydrogen sulphide spattered the newly painted decor and changed the colour from blue to dirty green! "
John Vane
End
Mother
Green
" Plainly, when perfusate from an organ or blood from an animal is used for superfusion, substances can reach the assay tissues within a few seconds of generation or release. "
John Vane
Animal
Within
Reach
" The medicines of today are based upon thousands of years of knowledge accumulated from folklore, serendipity and scientific discovery. The new medicines of tomorrow will be based on the discoveries that are being made now, arising from basic research in laboratories around the world. "
John Vane
Now
World
Tomorrow