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" No pill can help me deal with the problem of not wanting to take pills; likewise, no amount of psychotherapy alone can prevent my manias and depressions. I need both. "

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" I have had manic-depressive illness, also known as bipolar disorder, since I was 18 years old. It is an illness that ensures that those who have it will experience a frightening, chaotic and emotional ride. It is not a gentle or easy disease. "

Kay Redfield Jamison

Emotional

Experience

Ride

" Grief comes and goes, but depression is unremitting. "

" Lithium remains the gold standard, but many drugs now treat bipolar disorder. Medication is critical and should be combined with psychotherapy. Compliance is a major problem. Patients believe that once they're better, they no longer need the medication. It doesn't work that way. "

" We expect well-informed treatment for cancer or heart disease; it matters no less for depression. "

" A possible link between 'madness' and genius is one of the oldest and most persistent of cultural notions. "

" I love animals, and I was always attracted to the idea of being a zoo veterinarian or a veterinarian with the circus. "

" I say I'm an academic: a professor of psychiatry at Johns Hopkins. And I write. "

" I believe that curiosity, wonder and passion are defining qualities of imaginative minds and great teachers; that restlessness and discontent are vital things; and that intense experience and suffering instruct us in ways that less intense emotions can never do. "

" Grief is so human, and it hits everyone at one point or another, at least, in their lives. If you love, you will grieve, and that's just given. "

" There is no common standard for education about diagnosis. Distinguishing between bipolar depression and major depressive disorder, for example, can be difficult, and mistakes are common. Misdiagnosis can be lethal. Medications that work well for some forms of depression induce agitation in others. "

" When public figures remain silent about depression, there is a cost to the rest of society. Silence contributes to the misperception that successful people do not get depressed, and it keeps the public from seeing that treatment allows many individuals to return to competitive professional lives. "

" Knowledge is marvelous, but wisdom is even better. "

" There are a lot of studies that suggest a higher rate of creativity in bipolars than the general population. "

" I think one thing is that anybody who's had to contend with mental illness - whether it's depression, bipolar illness or severe anxiety, whatever - actually has a fair amount of resilience in the sense that they've had to deal with suffering already, personal suffering. "

" When I'm talking about depression, I'm talking about the more severe forms of depression, and I think that conceptualising as a form of grief is probably not the most effective way of looking at it. I mean, at the end of the day, people suffer enormously, and you want to treat it. "

" It is important to value intellect and discipline, of course, but it is also important to recognize the power of irrationality, enthusiasm and vast energy. "

" Mania is as bad as it gets. If not treated, it will become worse, more frequent, and harder to treat. "

" You become aware of an illness by understanding yourself and understanding the meaning that that illness has in your own life, symbolically and, more importantly, quite literally. "

" Psychotherapy is a sanctuary; it is a battleground; it is a place I have been psychotic, neurotic, elated, confused, and despairing beyond belief. "

" Several politicians and wives of politicians have been public about their experiences with depression or bipolar illness, including Lawton Chiles, Patrick Kennedy, Tipper Gore and Kitty Dukakis. Each made a tremendous difference by doing so. "

" Moods are complicated and very much a part of who we are. People would be very boring without them. "

" People talk about grief as if it's kind of an unremittingly awful thing, and it is. It is painful, but it's a very, very interesting sort of thing to go through, and it really helps you out. At the end of the day, it gets you through because you have to reform your relationship, and you have to figure out a way of getting to the future. "

" Because I teach and write about depression and bipolar illness, I am often asked what is the most important factor in treating bipolar disorder. My answer is competence. Empathy is important, but competence is essential. "

" It is an odd thing, owing life to pills, one's own quirks and tenacities, and this unique, strange, and ultimately profound relationship called psychotherapy. "

" I am one of millions who have been treated for depression and gotten well; I was lucky enough to have a psychiatrist well versed in using lithium and knowledgeable about my illness, and who was also an excellent psychotherapist. "

" Never once, during any of my bouts of depression, had I been inclined or able to pick up a telephone and ask a friend for help. It wasn't in me. "

Kay Redfield Jamison

Friend

Depression

" Confidentiality is an ancient and well-warranted social value. "

" There are scientists all around the world looking for the genes responsible for bipolar illness and major depression. "

" In some cases, some people do get depressed in the middle of their grief, and they really need to be treated for depression. "

" It's more common than not that bipolar illness will start in the teens. One of the reasons I spend a lot of time on college campuses is exactly that reason. It's terribly important to talk to students about knowing these things in advance. "