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" Not a big sci-fi guy. "

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" I was raised on 'Get Smart' and 'All in the Family' and 'M.A.S.H.,' and certainly when 'Cheers' came along, that was a big one. "

" We see people talking to themselves all the time. We always have. Particularly if they're homeless people or at all questionable, there's a sense of, 'That guy's crazy!' I see that now with a much more empathetic eye. "

" I didn't want to do a lawyer. I didn't want to do forensics. I didn't want to work in an ER. "

" My wife is a real camper; it's a nice way to bond. "

" We didn't, with 'Will & Grace,' set out to change the gay world. We just set out to be funny. "

" I knew I wanted to be an actor in first grade. "

" I do love the stage, and that is incredibly rewarding. "

" I have to challenge the audience. "

" I think it's about finding the character you want to play and the people you want to work with. "

" You can write your own history. "

" I saw 'Othello' with Christopher Plummer and James Earl Jones. "

" Will Truman will be on my epitaph, but as an actor, I have to challenge myself. "

" It's very strange - several years ago, I was in the running for the 'Young Frankenstein' musical. Kristin Chenoweth was going to do it, but then she backed out because she got 'Pushing Daisies' on TV, and then, the next day, I went in for my final-final audition, and I saw Megan Mullally standing there. "

" When I was 16, I'd ping pong between AC/DC and Barry Manilow without any sense of irony. "

" At home in L.A., Sunday is lazy. It's the wife and me lying in bed with coffee, watching 'The Soup' or something funny on TiVo. The kid will occasionally join us. Eventually, breakfast is at a place down the street called Paty's. And we always have some kind of great dinner - my wife makes a great roast beef. "

" It's hard in this business to get the opportunities to show off range. "

" It's very, very hard to create something that is big these days because you have niche markets - and, you don't necessarily need to be big; the show is specifically created for a small group of people. You know, if it's on the USA network, well, then a small group of people is fine. "

" But I was ready for it and I knew I could do it. I've just turned 40, I have a son and I feel more settled and driven than ever. I think my 40s will be my most prolific time. It's a very rare life you get to lead as a sitcom guy. "

" If you can last long enough, in success, you have to get really creative and come up with new stuff. "

" I'm still mad at Josh Charles for dying on 'The Good Wife.' "

" I find that with every script I get, I go, 'Who knew this? This is so cool!' "

" As much as I loved Pacino and De Niro and wanted to be a dramatic actor, I also grew up on sitcoms. I grew up on 'M*A*S*H' and 'All In The Family' and 'Cheers.' And then around this time - this would have been '95, '96 - I was so into 'Friends' and 'Mad About You,' the idea of being on a sitcom became a very real thing that I wanted. "

" I'm doing a very funny show in which we talk about issues. I speak at Aids charities and things. It's great to do something fun with our days and yet we're told we're doing something important. "

" When I read the script for Will & Grace in 1998, I knew I was the only guy for the part. "

" There wasn't an episode of 'Will & Grace' that didn't begin with my voice saying, 'Will & Grace' is taped before a live studio audience. "

" I know where TNT's sweet spot is, and when I read 'Perception,' I thought, 'This is a chance to play a fascinating, fun, challenging character but still within the realm of something that will sit very well with 'The Closer' and 'Major Crimes' and the other shows there.' "

" That's the hard part of television: When you walk into the network tests, you're signing away seven years of your life. "

" I love everybody at TNT, and they were totally behind 'Trust Me.' I totally loved that show. I feel like it should have had more life. "

" I haven't had a chance to play a quiet leading man in a while. "

" I did a film a couple years ago called 'Who Is Clark Rockefeller?' It was a role that I was really proud of that I wish more people could go back and rediscover. "