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" Personally, I'd like to see more of our leaders take a technocratic approach to solving our biggest problems. "

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" Exposure from a young age to the realities of the world is a super-big thing. "

" In ninth grade, I came up with a new form of rebellion. I hadn't been getting good grades, but I decided to get all A's without taking a book home. I didn't go to math class, because I knew enough and had read ahead, and I placed within the top 10 people in the nation on an aptitude exam. "

" I can understand wanting to have millions of dollars; there's a certain freedom, meaningful freedom, that comes with that. "

" Unemployment rates among Americans who never went to college are about double that of those who have a postsecondary education. "

" I'm an investor in a number of biotech companies, partly because of my incredible enthusiasm for the great innovations they will bring. "

" The potential financial reward for building the 'next Windows' is so great that there will never be a shortage of new technologies seeking to challenge it. "

" We always overestimate the change that will occur in the next two years and underestimate the change that will occur in the next ten. Don't let yourself be lulled into inaction. "

" No one person controls Microsoft. The board and the shareholders decide whether they want to have me as CEO. "

" The PC has improved the world in just about every area you can think of. Amazing developments in communications, collaboration and efficiencies. New kinds of entertainment and social media. Access to information and the ability to give a voice people who would never have been heard. "

" Treatment without prevention is simply unsustainable. "

" Employers have decided that having the breadth of knowledge that's associated with a four-year degree is often something they want to see in the people they give that job to. "

" If you count E-mail, I'm on the Internet all day, every day. "

" Nigeria has moved into low-middle-income, but their north is very poor, and the health care systems there have broken down. "

" The Global Fund is a central player in the progress being achieved on HIV, TB and malaria. It channels resources to help countries fight these diseases. I believe in its impact because I have seen it firsthand. "

" Being flooded with information doesn't mean we have the right information or that we're in touch with the right people. "

" It's a nice reader, but there's nothing on the iPad I look at and say, 'Oh, I wish Microsoft had done it.' "

" Polio's pretty special because once you get an eradication, you no longer have to spend money on it; it's just there as a gift for the rest of time. "

" Innovations that are guided by smallholder farmers, adapted to local circumstances, and sustainable for the economy and environment will be necessary to ensure food security in the future. "

" The protestor I think will speak up for the world's poorest. "

" I don't think culture is something you can describe. "

" In almost every area of human endeavor, the practice improves over time. That hasn't been the case for teaching. "

" I really had a lot of dreams when I was a kid, and I think a great deal of that grew out of the fact that I had a chance to read a lot. "

" I don't generally read a lot of fiction. "

" It's hard to improve public education - that's clear. "

Public Education

" Almost every way we make electricity today, except for the emerging renewables and nuclear, puts out CO2. And so, what we're going to have to do at a global scale, is create a new system. And so, we need energy miracles. "

" What destroys more self-confidence than any other educational thing in America is being assigned to some remedial math when you get into some college, and then it's not taught very well and you end up with this sense of, 'Hey, I can't really figure those things out.' "

" The malaria parasite has been killing children and sapping the strength of whole populations for tens of thousands of years. It is impossible to calculate the harm malaria has done to the world. "

" The main thing that's missing in energy is an incentive to create things that are zero-CO2-emitting and that have the right scale and reliability characteristics. "

" It's possible - you can never know - that the universe exists only for me. If so, it's sure going well for me, I must admit. "

" OK, I have a nickname. My family calls me 'Trey' because I'm William the third. My dad has the same name, which is always confusing because my dad is well known, and I'm also known. "