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" Startups allow technologists and scientists to take risks and change plans in a way that would be frowned upon in a big company. Having said that, big companies will play a key role in certain areas and in partnerships with little companies. Each has its strengths. "

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" I generally disagree with most of the very high margin opportunities. Why? Because it's a business strategy tradeoff: the lower the margin you take, the faster you grow. "

Vinod Khosla

Opportunities

Strategy

Business

" I'm not a political person. I'm a techie nerd, and I enjoy the techie part. I mean, all my life, I've loved great technology. "

" Now it will take a long time to scale biofuels, but I'm the only one in the world forecasting oil dropping in price to $35 a barrel by 2030. I'll put it on the record: Oil will not be able to compete with cellulosic biofuels. If you do it from food, the food will get so expensive you can't make fuel out of it. "

" The winter period between September and March in this country, when land sits fallow and is subject to topsoil loss, we could be enriching the soil and growing all the biomass we need to replace imported gasoline. "

" Everybody else is afraid to fail. I do not really care because when I fail, I try something new. "

" The combination of brilliant ideas and entrepreneurial spirit should lead us to a safer and more secure future. "

Vinod Khosla

Spirit

Future

" If you have a carbon cap and trade system, there'd be an agreed-to limit the amount of carbon we emit. That changes the economic picture for fossil technologies and for the renewable technologies. It makes the renewable technologies more attractive and the fossils less attractive. "

" Electric cars are coal-powered cars. Their carbon emissions can be worse than gasoline-powered cars. "

" There are parts of the country in America, in the Midwest, where wind is a big resource, and we should absolutely use it. But to try and apply it nationally doesn't make sense. There are technologies that will work that are appropriate to certain regions. "

" I don't believe - till something radical changes that we are not on track to do - that hybrids are material to climate change. They're fashionable, everybody loves them, the Prius is selling well, but so are Gucci bags. But they don't impact the way the world carries stuff. You know it's a fashion statement. "

" I don't know a startup that hasn't been through tough times. "

" Religion asks you to believe things without questioning, and technology and science always encourage you to ask hard questions and why it is important in science and technology. So I was always interested in science and technology. "

" The U.S. has fallen well behind Europe in recognizing climate change and the implications of climate change. "

" Your willingness to fail is what will let you succeed. "

" You know, one of the great things about most renewable technologies - not every technology, but many of them - is the jobs have to be local. When you're talking about a power plant and power generation using solar thermal technology, the jobs will be where the plant is. "

" Is it 10 years, 20, 50 before we reach that tipping point where climate change becomes irreversible? Nobody can know. There's clearly a probability distribution. We need to ensure this planet, and we need to do it quickly. "

" If everyone played it safe, we wouldn't get anywhere. "

" Will biofuel usage require land? Absolutely, but we think the ability to use winter cover crops, degraded land, as well as using sources such as organic waste, sewage, and forest waste means that actual land usage will be limited. Just these sources can replace most of our imported oil by 2030 without touching new land. "

" Germany has a lot of solar power. In fact, in 2005, some 55 or 57 percent of worldwide installations were photovoltaics in Germany. That's 57 percent of all worldwide solar photovoltaics. Because of the high feed-in tariff, they have a way of allowing you to produce electricity and ship it into the grid at very high prices. "

" Entrepreneurs can benefit a lot from the right help and advice, and you can avoid costly mistakes. You can get incredible leverage in hiring people who wouldn't even talk to you if you have the right help. An investor isn't about money - it's about the help and advice you can get. "

" Knowing whose advice to take and on what topic is the single most important decision an entrepreneur can make. "

" Certain food-based biofuels like biodiesel have always been a bad idea. Others like corn ethanol have served a useful purpose and essentially are obsoleting themselves. "

" We like to say at Khosla Ventures, and this is one of the reasons to do what we do, we'll take technical risks that nobody else will. "

" I do not know what got me interested in technology. What was very clear to me very early on was that I was not interested in religion and that naturally increased my curiosity about science and technology, and I fundamentally believe the two are conflicting. "