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" The principle of treating cancer is to kill the abnormally dividing cells. Many drugs achieve this in a relatively unselective way, killing any cell that is dividing. "

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" We may know the chemical structure of medicinal drugs, but we frequently have a very incomplete understanding of how they work. "

Mark Walport

Understanding

Work

Know

" Many families would like to avoid burdening future generations with inherited diseases such as haemophilia or severe developmental disorders. But most would think it wrong to edit the genes that influence the 'normal' range of human variation, from eye colour to intelligence or athletic ability. "

" Public trust is a vital condition for artificial intelligence to be used productively. "

" Distributed ledgers are inherently harder to attack because instead of a single database, there are multiple shared copies of the same database, so a cyber stack would have to attack all the copies simultaneously to be successful. "

" Science, engineering, and technology discovers and invents new ways of doing things - but it doesn't dictate how we should do them. "

" I look forward to working closely with the Research Councils, Innovate UK, and Higher Education Funding Council for England (HEFCE), as we work together to create UKRI. I also look forward to working closely with all of our research and innovation communities to provide a strong and coherent voice for U.K. science and innovation. "

" Common sense, proportionality, and judgment are the skills we must seek in those we choose to regulate our lives. "

" It would be silly not to admit that there are some sections of the public who are unconvinced by the benefits or have doubts about the motives behind it. We have to be clear that GM is not all about profits for multinational companies. "

" The problem of poor vision has gone unnoticed for too long - it's astounding that 700 years after glasses were first invented, there are still 2.5 billion people across the world without access to something as simple as eye screening or a pair of glasses. "

" Science, engineering, and technology have transformed the infrastructure of the modern world and have a vital role to play at the heart of policy making. "

" We pretend that the debate about genetically modified crops is a debate about science when the reality is, actually, that the science is very clear. It is really a debate about values. "

" We need to show why the government should be funding science and how that funding delivers. "

" If you look at U.K. science, we collaborate with people across the whole world, and it's extremely important we continue to do so in the future. "

" The best approach to risk is to identify and manage it. "

" Forensic science offers great potential, as it draws on almost every discipline and, in doing so, creates widespread opportunity for innovation. "

" New technology creates a new marketplace of words, creating totally new words and changing the meaning and application of existing ones. In doing so, it has a potent opportunity to create new misconceptions and confusion. "

" Forensic techniques are enormously useful in a wide range of fields outside the criminal justice system. "

Mark Walport

Justice

System

Criminal Justice System

" Banks and credit agencies learn continuously about the purchases we make. This is convenient and diminishes the risk of theft. It also means that banks can know more about our lifestyle than our close relatives. "

" It seems paradoxical that, as medical scientists make huge advances in discovering the mechanisms of common diseases, fewer and fewer innovative drugs are reaching the market. "

" We all want our drugs to be safe - and so an essential part of the pathway to the development of a new drug is approval by a regulator. "

" A computer, by definition, cannot be held accountable for anything because there is no mechanism to hold it to account, short of turning off the electricity supply or destroying the hardware. Only humans can be accountable. "

" There is a particular set of values commonly associated with being professional. Experience, expertise, trustworthiness, wisdom, and good judgement are all attributes aspired to by senior professional people, be they doctors, engineers, lawyers, civil servants, or the clergy. "

" I am honoured to be appointed as the first chief executive of UKRI. My ambition is to make UKRI the world's leading research and innovation public funding agency. "

" Research must be central to healthcare if healthcare is to improve. "