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" There's nothing wrong with being driven. And there's nothing wrong with putting yourself first to reach your goals. "

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" In my house, you got in trouble if you didn't speak up. My mom would be furious at us if we went to school and behaved nicely if someone treated us badly. If we got in trouble because we had yelled at them or told them that they were wrong, my mother would be like, 'Good job.' "

" I think that women are raised to believe that they're supposed to want certain things, and so you feel like you're supposed to apologize when you don't want those things. "

" When you help make people healthier, it makes the nation healthier; it makes the world healthier. It makes the economy healthier. "

" I'd split up with a boyfriend and gone to Vermont to stare at my navel, and then 9/11 happened, and I spent days being scared of what was happening in the world. So I made a list of all the things I wanted to do, and at the top was adopt a baby. Nine months and two days later, I brought my daughter home. "

" My 15-year-old threw open the door the other day to my room and screamed, ''Freaks and Geeks' only has one season? Can they make another one?' And I tried to explain to her that it happened a long time ago. She didn't understand that because it felt very relevant to her. "

" Work doesn't work without play. "

" When the press began asking me for interviews, I freaked out. My instinct is to hide. "

" I think the point of our country, our planet, the reason we're all here, one of the best things that we can do is be concerned about something even when it doesn't concern us. That's the whole point. "

" I work for ABC. If the thing that ABC is paying me for is storytelling - not to make sure that a costume is exactly right or all those other things - then it is up to me to find the most creative space possible so that that function of my job can happen. "

" Sometimes people don't want to be empowered because they are afraid of being the person to make the decisions. "

" I learned how to write TV by writing 'Grey's Anatomy.' "

" You have to have more people who don't look like you in the writers room. I try to have some people who don't look like me in my writers room. I think it's important to have a group of voices, of people who can dissent. "

" What I found fascinating for me was, I've never gotten so much approval and accolades and warmth and congratulations as when I had a guy on my arm that people thought I was going to marry. It was amazing. I mean, nobody congratulated me that hard when I had my three children. "

" When I'm hard at work, when I'm deep in it, there is no other feeling. For me, my work is at all times building a nation out of thin air. It is manning the troops. It is painting a canvas. It is hitting every high note. It is running a marathon. It is being Beyonce. And it is all of those things at the same time. "

" I actually really love Twitter - I used to feel angry and insulted when people criticised me or the shows, but now I don't take it too seriously. What I do love is that there's this great direct line to fans. "

" My poor children have been the subject of all of my experiments. We're still doing what I call 'Amish summers' where I turn off all electronics and pack away all their computers and stuff and watch them scream for a while until they settle down into, like, an electronic-free summer. "

" After I lost weight, I discovered that people found me valuable. Worthy of conversation. A person one could look at. A person one could compliment. A person one could admire. A person. "

" This is going to sound crazy, but there was a period of time where on TLC they would show those surgeries - like a woman had a 90-pound tumor, or they separated these twins. And my sister and I - she lived in Ohio when I lived in California - would watch them together on the phone. "

" I don't think of myself as a television producer. Obviously, that's crazy. Because I should. That's what I do. But I don't actually see that as my job. It's why my business cards say 'storyteller.' "

" I believe that good television should be challenging and frustrating and maddening and thrilling. If you just want to see people who look like you and think like you and do what you would do in any given situation, you'd have to stop looking at TV and start looking in a mirror. But would that be as much fun? "

" You don't necessarily have to watch something for 14 seasons. It's not necessarily the way everything's supposed to be. "

" I can't change the past. It made me what I am. "

" I've never personally had to use a Planned Parenthood. But I have many friends who have and do and did, and I think it's important that that access be there for everyone. "

" I like working more than I like being at home. Facing that fact is incredibly difficult to handle, because what kind of person likes working more than being at home? "

" I actually like being alone. I spend most evenings reading and taking long baths. "

" Having a strong sense of self is fundamental to you, no matter what you're doing. I don't care if you're a stay at home mom raising kids or if you're the CEO of a corporation. It's really important for your survival. "

" I never, ever pay attention to the ratings. I stopped paying attention to the ratings somewhere around season two or three of 'Grey's.' It's something I have no control over, so I don't even pay attention. "

" You can't tell stories and really walk in someone's shoes and not have a love for them, even if they're doing horrible things. "

" Frankly, the idea that we need to be beautiful, if you really think about it, it's odd. But if you can turn it inward and see yourself as beautiful, that's what changes the world. "

" The secret sauce of the business that I can offer is my creativity, and in order to keep my creativity alive and fresh, I have to pretend that no one is watching the show, that there are no audiences, there are no ratings; I'm just telling a story. "