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" When you're at your absolute, most exhausted... That's when you have to be at the top of your game. "

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" I work a lot, and it's kind of like, you meet people, and you just click. It's not like I'm looking at something and thinking: 'South Park' - how do I get on that?' I just became friends with those guys first. They're nice guys. "

" I can't do Twitter or Facebook, mostly because I feel like I'm the type of person who has to regiment the amount of time I spend doing certain things or I'll just wade in it, and then I'll never come out. "

" I moved out to L.A. to be a filmmaker or director. I didn't even think about doing comedy or even acting. I wanted to be like Paul Thomas Anderson or Wes Anderson, but I wasn't going to a lot of comedy. "

" My wife and I were on our honeymoon in Turks and Caicos, in the middle of nowhere, and I'm sitting on this deserted beach, and I see one lone person walking along the shore. He walks right up to me and says, 'I love 'Laser Cats,' and then just walks away. "

" Let's face it: I look pretty out of shape. "

" Good directors give short and specific instructions to their actors. "

" I remember seeing 'Spinal Tap' at a young age and being like, 'That's how you perform comedy.' "

" I took Second City out of desperation, and that's what ended up working out. It shows that you should be doing a lot of different stuff, taking whatever opportunities are there, to see what works. "

" I don't think I could do what Woody Allen or Clint Eastwood or Ben Stiller do, where they direct a movie and they star in it. I would just be like, 'Oh, I don't even want to look at my face.' "

" I just did this movie with Kristin Wiig called 'The Skeleton Twins.' That's a straight drama. We play estranged twins, and I end up moving in with her and her husband, played by Luke Wilson. But it's a drama, and the Duplass Brothers produced it and this great guy, Craig Johnson, directed it. And that was great, you know? "

" I get migraines a lot. I get them when I'm stressed out. My brain freezes, and I just try to get through that. "

" I remember I could do - I did Bart Simpson once on the bus. I did, like, a really good Bart Simpson voice on the bus, obviously before I hit puberty. And everybody went, 'Whoa, that sounds just like Bart Simpson.' "

" For our anniversary, my wife and I went to see Godzilla, and then we ate at Barnyard Venice, and it was like, 'We are crazy! The Kardashians have to keep up with us!' "

" My parents were supportive. I didn't have good grades, but they could tell I wasn't lazy. "

" Going to any loud place is terrible for me. I'm bad at loud restaurants. "

" When you saw Jon Lovitz or Dana Carvey or Phil Hartman doing something, they were acting. It was real acting. Like, they were acting like that person. They weren't like - it wasn't even like they were really trying to go for a laugh, especially in Phil Hartman's case. "

" Yeah, improvising only really works 100% when you're with somebody. "

" Everything is so tech now; everyone is so connected that way. "

" A lot of times I think people, when they're doing a movie that's a family movie, they're worried about this being too esoteric or too dark or too weird. "

" Fred Armisen does a pretty good me. "

" When it comes to comedy, it might be interesting to know why an airplane works, but really? Maybe it's better not to know why certain things work. Just fly the thing, and if nothing falls apart, you'll be fine. "

" I have a lot of incomplete short films and incomplete scripts out there. "

" To be totally honest? I don't know if I'll keep doing more impressions. People told me I had a facility for it, and I was like, 'Okay, I'm the impression guy.' So you imagine the cast at 'SNL' is an A-Team, and you've got the explosives guy, and I'm the impression guy. "

" I got invited to the Playboy Mansion with the Lonely Island guys after their first season on 'SNL,' and I sat in the corner drinking coffee and talking to Akiva Schaffer about what aspect ratio he was going to shoot 'Hot Rod' in. Like, that's what we talk about. "