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" Believe it or not, perhaps I don't show it much, or well, but I think I like people. "

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" I feel like a hostage to fortune. Not that I am complaining. I wanted to play the role. But in truth I didn't think the show would be such a success. OK, I thought it would fail. Not because it was bad. I was confident it was good, but plenty of good things just sort of wither on the vine. "

" One of the principal goals in my life has been to avoid embarrassing my children by doing the job I do. I hope I've managed to do that, and I hope that, with the job I'm in now, they are, if not proud, at least unembarrassed by it. I must say, my three are most agreeable children, who do nothing but delight me. "

" They're very harsh people, the British: hard to impress, very tough on each other, but I rather like that. It's not that the British are more honest - you're just under no illusion with them. "

" It's easier for a camel to pass through the eye of a needle than for a rich man to make a blues record. "

" I don't think of myself as funny. I think of myself as rather grave, actually. And I'm suspicious of fun. I never quite know what that is or how to deal with it or how to generate it. That's my fault. I know it's a burden on the people I'm with. It's tiresome. "

" Piano was - well, all musical instruments were taught in this very rigid, formal, classical method when I was young. "

" The great trap for non-American actors trying to play Americans, I think, is to start thinking of American-ness as a characteristic. It isn't. It is no more a character trait than height. It is just a physical fact, and that's all there is to it. "

" My dad gave me my first bike at 16. I soon fell off and was in a wheelchair for weeks. I haven't fallen since. "

" When the ship goes down, the waves very quickly roll over the top of it, and attention shifts elsewhere. It's just the natural order of things in TV - in life - and is as it should be. "

" I have been instrumental in banning bottled water on the set. It hasn't gone that well with the crew... so I replaced it with tequila. "

" I think good-looking people seldom make good television. And American television studios almost concede before they start: 'Well, it won't be good, but at least it'll be good-looking. We'll have nice-looking girls in tight shirts with F.B.I. badges and fit-looking guys with lots of hair gel vaulting over things.' "

" I think maybe even one of the reasons I became an actor was actually to hide. I mean, it sounds paradoxical because, of course, people are standing up in a public place and encouraging other people to look at them. So that's not the conventional definition of hiding. "

" I am a coffee fanatic. Once you go to proper coffee, you can't go back. You cannot go back. "

" Riding my motorcycle around L.A. is like my own video game. But unlike many folks at the wheel, I am occupied with getting where I'm going and keeping myself safe. Most people are applying makeup, texting, and checking out the beauty in the next car. "

" Screenwriting is the most prized of all the cinematic arts. Actually, it isn't, but it should be. "

" I never went to drama school, I don't have any certificates saying: 'He's a qualified actor.' But I did think that 'House' was something I didn't have to apologise for. It was something I was really proud of and it was sort of... whether you liked it or not, it was undeniable. "

" Muddy Waters, I suppose, was my first great hero. You know, every boy wants to be a guitar player, and Muddy Waters was just the king. He was the King Bee. He was it. "

" I have resolved to pick one novel and just read it over and over again for the rest of my life, because I cannot remember anything anymore. "

" I never was someone who was at ease with happiness. "

" I just read an 800-page history of the Scottish Enlightenment and, honestly, I may as well just start it again now, because I cannot remember a single thing. I can barely remember where Scotland is. "

" I'm finding it increasingly difficult to simply walk down the street. In New York, I dashed in to buy a big pair of sunglasses to conceal myself, but the guy behind the counter shouted 'Hey! It's Dr. House.' "

" As a real person, he wouldn't last a minute, would he? But drama is about imperfection. And we've moved away from the aspirational hero. We got tired of it, it was dull. If I was House's friend, I would hate it. How he so resolutely refuses to be happy or take the kind-hearted road. But we don't always like morally good people, do we? "

" I really do believe the camera steals the soul. But that may be because I'm worried about my soul. I don't have much of a soul to begin with; I can't afford to lose much. "

" Humility was considered a great virtue in my family household. No show of complacency or self-satisfaction was ever tolerated. Patting yourself on the back was definitely not encouraged, and pleasure or pride would be punishable by death. "

" Even the greatest poets, I think, cannot quite get to the places that music can get to in the human - I was gonna say mind, but it's actually the entire body. It somehow seems to infuse the entire body. "

" I think pain is a very - it's an extremely hard thing to empathize moment to moment. And you often don't remember your own pain, you know, that moment that you broke a limb or you burned yourself or, I think, this is a common thing that women talk about with childbirth, that the memory of the pain is hard to summon up and relive, thankfully. "

" L.A. runs on optimism, enthusiasm and flattery. I think you can go a little bit crazy. I've heard people say there's a limit to the number of years you can stay in this city without going slightly mad. It's just too damn sunny in every dimension - weather-wise, socially and professionally. "

" People will survive, and they will find happiness. Happiness only comes when you're not looking for it. "

" I run six-to-eight miles a day, plus weights and aerobics in the lunch hour. I also lie a lot, which keeps me thin. "

" I don't have a single complete show or movie or anything else that I could look at and say, 'Nailed that one.' But endless dissatisfaction is, I suppose, what gets us out of bed in the morning. "