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" 'Grey's' has this universal, global thing to it. It works all over the world. "

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" I like people with their own opinions, and I like people who argue with me. It's very exhausting to be in a room full of people who just nod and smile. "

" Disney has made $2 billion on 'Grey's Anatomy.' I don't have $2 billion. "

" When the press began asking me for interviews, I freaked out. My instinct is to hide. "

" These days, I feel like a chunky spy in a thinner world. Strangers tell fat jokes in front of me. Jokes not meant for me. But... completely for the woman I used to be 150 pounds ago. The woman I could be again one day. The woman I will always be inside. Because being thinner doesn't make you a different person. It just makes you thinner. "

" There is a part of me that's oblivious. People always ask me, 'What obstacles have you faced?' and I always think, 'What are you talking about?' Whether or not there were obstacles, I never saw obstacles. It's never occurred to me that I wasn't good enough for something. "

" The beauty of being a feminist is that you get to be whatever you want. And that's the point. "

" There's nothing wrong with being driven. And there's nothing wrong with putting yourself first to reach your goals. "

" It's important to have people who are absolutely willing to say you're wrong or who have a totally different perspective than you do on everything. Fresh ideas are hard to come by, and good ones are even harder. "

" That first year I was doing 'Grey's,' I didn't know it was possible to fire the creator of a show off their own show, so I didn't behave like somebody who was afraid of being fired. "

" There are stories to be told that are still untold and characters to be portrayed that haven't been portrayed correctly. So there's work to be done. "

" For me, beauty is me at the top of my game, going as hard as I can, without fear of what anyone else thinks. Believing in yourself when nobody else is believing in you is half the battle about anything. "

" I actually like being alone. I spend most evenings reading and taking long baths. "

" Shondaland is my company. I run that mother. I am in charge. I am the leader. It's fantastic. It's also really hard. As it should be. "

" What I found fascinating for me was, I've never gotten so much approval and accolades and warmth and congratulations as when I had a guy on my arm that people thought I was going to marry. It was amazing. I mean, nobody congratulated me that hard when I had my three children. "

" There have to be practical steps. There's no point in holding out for a magic door because there are no magic doors. You can dream your life away or actually do what you dream of doing. That's the most valuable advice I can give. "

" I truly feel like my job is to make the shows. That's what I'm paid to do. It's somebody else's job to market them, and it's somebody else's job to pay attention to the ratings, because if I paid attention to all that, my head would explode. "

" I'm not a person who's interested in getting involved with politics just to get involved with them, and I don't need to. "

" The idea that the more you hide something, the more it becomes something that's supposed to feel shameful is very true. "

" I work for ABC. If the thing that ABC is paying me for is storytelling - not to make sure that a costume is exactly right or all those other things - then it is up to me to find the most creative space possible so that that function of my job can happen. "

" We have people say, 'There's not enough women writers.' I have a writers room that is almost nothing but women over at 'Grey's Anatomy.' "

" I have all these friends who just love therapy, and I always say the reason that I'm absolutely not in therapy is because then I wouldn't have anything to write. "

" My 15-year-old threw open the door the other day to my room and screamed, ''Freaks and Geeks' only has one season? Can they make another one?' And I tried to explain to her that it happened a long time ago. She didn't understand that because it felt very relevant to her. "

" Getting on a plane and discovering that your seat belt won't fit around you was a moment of extreme horror. It was very hard to ignore. "

" I believe that good television should be challenging and frustrating and maddening and thrilling. If you just want to see people who look like you and think like you and do what you would do in any given situation, you'd have to stop looking at TV and start looking in a mirror. But would that be as much fun? "

" A lot of people think that they are leaders just because they have been placed in charge of something - and you're not. "

" I have so much going on inside my head in terms of writing, there's such a large space in my life taken up by that. I can't imagine it being taken up by a husband and children and writing, and everything getting its due. I don't believe there is room for all of it. I really don't. "

" My worst trait is that I'm an introvert. When I've led stuff, the hardest thing for me to overcome has been my natural desire to run and hide. I'm very proud of the fact that I have been able to do that. "

" Why should I dislike anything about my appearance? I came off the factory line this way. I am perfect. "

" I say it in the writers' room all the time: My black is not your black. What's terrifying is that, just the same way we've all accepted that normal is white, everybody seems to buy into the idea that there's only one way to be black or one way to be Hispanic. That's as damaging as anything else. "

" This is going to sound crazy, but there was a period of time where on TLC they would show those surgeries - like a woman had a 90-pound tumor, or they separated these twins. And my sister and I - she lived in Ohio when I lived in California - would watch them together on the phone. "