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" How much do you engage yourself in what's truly real and important in life? That's the individual question. "

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" Address these environmental issues and you will address every issue known to man. And we keep dabbling in things that aren't really that important in the long term. "

" I've never been that guy who says, 'Ooh, I have to play King Lear'. First off, that'd be a disaster anyway. I tend to read something and see who's involved, and then know I want to be part of it. But I don't think I'm through with comedy. I still love to make people laugh. "

" I'm an actor, so I am always scared. You never know if you are on vacation or that you have been retired and they just didn't tell you. "

" I am so grateful that I accepted the offer to do 'CSI,' but it was like being shot out of a cannon, and it was so different from anything that I have ever done. "

" Usually if you're the center of a show, part of your job is to host its energy. "

" One of the hardest things for me to do is watch myself. The first time I see it, I am obsessed with my left ear or my right ear or some other physical attribute, or the fact that I'm 60 or whatever shallow ego thought is running through my head. I'm just destroyed that I'm not Cary Grant or whatever. "

" If you take one rivet out of an airplane, it will be all right, it'll keep flying. You take another rivet out of the airplane and it still flies. So what the heck, let's take more rivets out of the airplane, and sooner or later, the airplane drops from the sky. "

" To grow up knowing you're loved is astounding. It's a huge gift to a child. "

" I got my first television at Stanford when I was 20, and I used to watch 'The Dick Van Dyke Show'. He played my father on 'Becker,' and he's still one of my heroes. Along with John Cleese, he's my favourite physical comedian. "

" 'Cheers' was great. They paired me up with Shelley Long on this tiny bar set for the final audition. That was my first really big one, and we just clicked instantly - I still think I got the part because of Shelley. "

" When you have brothers, you learn to be fiercely competitive with someone you love so they won't kill you and you won't kill them. "

" When people are in the midst of really heavy stuff and still have a sense of humor, I admire that. "

" I feel very strongly that you can't just beat people up anymore; you have to work hand in hand and find ways to compromise, and get big business involved, because it won't happen otherwise. "

" You use and lose a lot of energy being grumpy. "

" You reach a certain age, and you realize, 'Wow: there are younger people doing this better than I can, and don't leave me out - I don't want to be left behind. I want to do it, too. Where are you going? I want to be part of it.' "

" I try not to see Woody Harrelson because he has become this big movie star, and it grates, so I try and stay away from him. "

" Humor can bring people under the tent. And a good joke can deflect some of the intensity surrounding a serious subject. "

" I eat less, stretch, and work out. "

" Everything I am, everything I've been allowed to do, career-wise, has come out of the opportunity I had with 'Cheers'. I think it's one of the funniest shows ever. They are some of my best friends. "

" I was three. My father in jest said that he'd tell the doctor to give me a shot if I didn't behave. Good heavens, I have a mental picture of the living room and the doctor approaching the door. I was terrified. "

" My job playing Sam Malone was to let the audience in, to love my bar full of people. And that informed my life. "

" We're not trying to reinvent the wheel; for any environmental organization to claim sole responsibility for any kind of victory is insane, because everybody attacks these problems as a group. "

" I'm basically a know-it-all, and I'm writing a book about it. I want it to be called 'Danson on Water' and have me on the cover in this Christlike pose, standing on the water. "

" I'm almost tempted, when I'm playing a real person, not to meet them. Afterwards, maybe. But, the job is the same. You still have to show up on screen and be alive and real and all that stuff. "

" My father went to work every day, and it's my job to go to work, too. Some days will be good, some won't be so good, but I have to go to work. "

" If you actively do something, it will stop making you feel like a victim and you'll start feeling like part of the solution, which is just a huge benefit to your body and your psyche. "

" The planet will survive. Whether we get to be here and enjoy it, or enjoy life as we've known it, is what's questionable. "

" I was at our beautiful home in Martha's Vineyard, near Boston, sitting on the porch looking at the ocean when I got a phone called and was asked, 'Would I like to do 'CSI'?' A week later, I'm at a coroner's office in Las Vegas, participating in a quadruple autopsy. "

" To do something funny, you have to have experienced it in real life and digested it in a way that amuses you. "

" The industrial way we fish for seafood is harming the marine habitats that all ocean life depends upon. Indiscriminate commercial fishing practices that include miles of driftnets, long lines with thousands of lethal hooks and bottom trawls are ruining ocean ecosystems by killing non-seafood species, including sea turtles and marine mammals. "