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" I hope that dog lovers around the world will support the Cruelty Free International global campaign to end the use of dogs in outdated and cruel experiments. "

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" It's hard in this business to get the opportunities to show off range. "

" I love everybody at TNT, and they were totally behind 'Trust Me.' I totally loved that show. I feel like it should have had more life. "

" I haven't had a chance to play a quiet leading man in a while. "

" With these scripts and these writers, so much of it is done for me. Because we don't just throw words around: we make sure the audience understands. "

" If you're doing an hour-long show, you're working movie hours, doing a 12-15-hour day. We work three or four hours a day, and get every third or fourth week off to give the writers time to write. It's the cushiest job in Hollywood. "

" I never felt cool growing up. I was a bit of an outsider, but I discovered theatre very early on, which got me through. "

" Unfortunately, with men's health, we don't talk about it enough, and prostate cancer gets lost in the conversation. "

" Particularly in television, we can stereotype ourselves. You realize that we all have a lot of voices in our head. We have angry voices, we have voices of doubt, and we have moments of strength. "

" I think it's about finding the character you want to play and the people you want to work with. "

" When I read the script for Will & Grace in 1998, I knew I was the only guy for the part. "

" I knew I wanted to be an actor in first grade. "

" Tom Cavanagh is fantastic. "

" That was the only trepidation I had about 'Will & Grace.' It had nothing to do with the sexuality of the character. It was more, 'This could be the next 7 to 10 years of my life.' "

" I didn't want to do a lawyer. I didn't want to do forensics. I didn't want to work in an ER. "

" My second year of Ryerson, I still lived at my folks' place. I went to the attic to find some prop for a play I was doing. And I found a scrapbook dedicated to my father's years at Ryerson as an actor. He never mentioned it. "

" Because I had three years on 'Perception,' I think I succeeded in showing I can do other things, and I can create a different audience, even from people who loved 'Will & Grace.' "

" Will isn't a screaming queen - that's Jack's part. They needed someone to play the part for America. It's just not the same as Britain. To have a gay character as a lead is risky. "

" You can write your own history. "

" Mental illness is the last frontier. The gay thing is part of everyday life now on a show like 'Modern Family,' but mental illness is still full of stigma. Maybe it is time for that to change. "

" The Trevor Project provides crisis-intervention and suicide-prevention services to lesbian, gay, bisexual, transgender, and questioning teens and young adults. It's truly a lifeline to so many young people who just need someone to listen to them. "

" As a television actor, there's a power you're given to use your image to do something valuable. As a parent, these messages are particularly important to me. "

" 'Monk''s gone, and 'House' is gone. Maybe I can pick up where they left off. "

" Certainly 'Lonesome Dove' would be way hard now, because, I mean, back then I wasn't married. I didn't have kids. "

" I have to challenge the audience. "

" Growing up, my father was a financial analyst for an oil company. He was just a regular dad. And when I would say, 'Hey, come see my play,' he'd say, 'Sure.' He'd see one, 'Oh, good play' - you know, very typical dad reaction. "

" I would come home with my friend Bill, and we would sit and watch 'Get Smart.' And I was Agent 44, and he was Agent 85. And it was a fantastic - and all we wanted to do was sleep with Barbara Feldon. "

" I like playing a character every day. I like having something to go back to. I always enjoyed that with 'Will & Grace.' I like the camaraderie. I like having a crew that I know and I can work with every day. "

" We want all LGBTQ kids to grow up in a world where they feel safe and equal to their straight peers. "

" As much as I loved Pacino and De Niro and wanted to be a dramatic actor, I also grew up on sitcoms. I grew up on 'M*A*S*H' and 'All In The Family' and 'Cheers.' And then around this time - this would have been '95, '96 - I was so into 'Friends' and 'Mad About You,' the idea of being on a sitcom became a very real thing that I wanted. "

" We see people talking to themselves all the time. We always have. Particularly if they're homeless people or at all questionable, there's a sense of, 'That guy's crazy!' I see that now with a much more empathetic eye. "