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" It's spelled, like, S-E-R-G. I always thought it would be funny if I called my son 'Sir.' Like calling your daughter 'Ma'am,' or something like that. "

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" I just like to keep things small and subtle and authentic, and ground everything in reality. So that is something that I feel is my strength as a director and I try to achieve as an actor. "

" You can't regulate what these kids are being exposed to on the Internet. It's so way out of control. All you can do is just try to talk to your own kids. "

" I want to create opportunities for women, of course. "

" I get up at 6 A.M., and sometimes I make lunch for my two youngest kids. Usually my oldest sleeps late, and I get my kids out the door to school. For years, it was me just doing all of that and then driving to a carpool or this or that. "

" The thing about women playing boys is that we're not going to age, and we're not going to go through puberty in the middle of a long-running series. "

" Before 'Lucky Louie,' nobody would ever cast me to play a mom or a wife; nobody ever saw me in that role, which is weird, since that's who I really am. "

" I don't think I have a demographic. I was at Comic-Con in San Diego recently, and I was doing a signing, and my line was all military guys, young girls, housewives and guys in wheelchairs. There was just everybody all over the place. "

" When I saw 'Louie' and 'Girls', I was blown out of the water. They were fearless portrayals of real life. Everyone has a different experience. "

" I took my daughters to see Plastic Ono Band at the Orpheum in L.A. in 2012. It was an amazing experience because she is such a revolutionary artist. Everybody was like, 'Oh, it's Yoko, it's such a joke.' But it's no joke what she did, visually and musically. It's incredible. "

" Sometimes when I'm in the editing room and there's a new person there, like a music editor or a post person that I don't really know, I'm like, 'Oh, you shouldn't be in here. This is too personal - you can't watch this.' But then I'm like, hey dummy, you're about to show this to the whole world. "

" My life is extraordinary because it's so normal, but it's so 'extra' for some reason. "

" I'm more of somebody who'll bend over backwards for people and, you know, wait at the back of the line until everybody's taken care of. That's really my nature. "

" One of the things I learned in animation is that you never, ever want to start doing a voice that you can't sustain for four straight hours. "

" My roles in the '80s were, like, gender dysphoric. I wasn't pretty, I wasn't this, I wasn't that. And I am kind of butchy, you know. That's just my thing. "

" For me, running a set and directing has been the most rewarding thing of my life and a happy surprise, because it was never really on my radar. "

" Cooking is the best occupational therapy for me. And when I cook, everybody comes to eat. It's the greatest thing. "

" I've been working since I'm 9 years old. "

" I learned so much from my life as an actor, as a kid actor through being an adult actor, and then becoming a writer and producer and doing animation. "

" The only people on this planet that can make me feel like my feelings are hurt are my kids. "

" Sometimes when I'm in the car driving, I scream at the top of my lungs. "

" I'm somebody who, if I went to the grocery store, and one of them wasn't with me, I would feel guilty. I would be like, 'I shouldn't be doing anything without them, anytime, ever.' A very codependent way of thinking. Also, motherhood is hugely about guilt. "

" It's a hilarious part of my past, all the sitcoms I did in the '80s. And then all the animation - animation is amazing. It's really been great. "

" They would call me 'The Cleaner' because I would replace boys who were real adolescents, and their voices completely changed, and they couldn't do the voices anymore. "

" I'm very influenced by documentary filmmaking and independent filmmaking, by a lot of noir and films from the '40s. Those are my favorite. And then, filmmaking from the '70s is a big influence for me. "

" I always tell young people when I'm trying to encourage them, 'You have certain windows in your life, and you have to take advantage of it. You gotta jump through because they will shut on you.' "

" You can go in and out of love and still love somebody, you know? You may not like them so much on the day, but I can tell you that I don't think I've ever been so vulnerable or been so angry in my life - like, those two emotions feel so hurt or so enraged - as when you're dealing with your kids. "

" If I'm doing a voice-over session, like animation or something, and I'm doing three different voices, you've gotta separate them. You've gotta find the different places and do your different things. "

" I love that, 'mommy-shaming.' When I was a new mom, I was obsessed with how I was being perceived and trying to fit in as a mom, going to mommy-and-me classes and things like that, and never quite measuring up to 'the real moms,' the 'robot moms,' as I called them. "

" I'm trying to keep my days very efficient, and I keep my set really tight. Every single corner is active, and everybody gets to thrive in the job that they do. I don't waste people's time. "

" 'Roseanne' was massive for me. I adored that show. I mean, the show was this couple who weren't cookie-cutter, and they were sexy, and we know that they like to have sex with each other, and they flirted, and then they ragged on their kids, and their kids ragged on them, and it was such a realistic depiction. "