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" There is an enormous amount of options that a physician can provide today, right down from curing patients, treating patients, or providing patients with psychic solace or pain relief. So, in fact, the gamut of medical intervention is enormous. "

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" Science is among the most profoundly human of our activities. Far from being subsumed by the dehumanising effects of technology, science, in fact, remains our last stand against it. "

Siddhartha Mukherjee

Science

Human

Last

" Most days, I go home and I feel rejuvenated. I feel ebullient. "

" In a spiritual sense, a positive attitude may help you get through chemotherapy and surgery and radiation and what have you. But a positive mental attitude does not cure cancer - any more than a negative mental attitude causes cancer. "

" The idea that cancer genes are sitting inside each and every one of our chromosomes, just waiting to be corrupted or inactivated and thereby unleashing cancer, is, of course, one of the seminal ideas of oncology. "

" I wanted to explore cancer not just biologically, but metaphorically. The idea that tuberculosis in the 19th century possessed the same kind of frightening and decaying quality was very interesting to me, and it seemed that one could explore the idea that every age defined its own illness. "

" I once set myself a deadline: half a chapter a week, 20 minutes a day. The thought froze me instantly, like literary Botox. I returned to my non-schedule: sleeping, writing 20 minutes, and then back to sleep. Breakfast in bed, with juice congealing on the sill: pages and pages began to pour out again. "

" The trick to my writing, it turned out, was doing so exclusively in bed. The minute I even dared to discipline myself and write at the desk, I produced mounds of nonsense. Yet, sitting in bed, I wrote easily, effortlessly, fluidly. I became the master of perfect indiscipline. "

" Mary Lasker was an entrepreneur; she was a socialite. She was kind of a legendary networker. She became interested in saying, 'Well, you know, if these diseases don't have political support we'll never conquer them.' And she made, really, cancer her special cause. "

" There is a duality in recognising what an incredible disease it is - in terms of its origin, that it emerges out of a normal cell. It's a reminder of what a wonderful thing a normal cell is. In a very cold, scientific sense, I think a cancer cell is a kind of biological marvel. "

" Because I work on leukemia, the image of cancer I carry in my mind is that of blood. I imagine that doctors who work on breast cancer or pancreatic cancer have very different visualizations. "

" If you take 100 breast-cancer samples, 100 types of cancer have 100 different hallmarks of mutated genes. You could be nihilistic and say, 'Oh, God, we'll never be able to tackle this!' But there are deep, systematic, organizational principles at work in all that diversity. "

" What we do in the laboratory is we try to design drugs that will not just eradicate cancer cells but will eradicate their homes. "

" I could write a thesis on the physiology of vision. But I had no way to look through the fabric of confabulation spun by a man with severe lung disease who was prescribed 'home oxygen', but gave a false address out of embarrassment because he had no 'home.' "

" I am a scientist and I am a physician. So I write papers. "

" Pharmacology is benefited by the prepared mind. You need to know what you are looking for. "

" Each of us knows a few or several young people whose lives have been devastated by cancer. I don't mean to be nihilistic about it, but it is very much an active killer of people now. "

" Nearly every one of the genes that turns out to be a key player in cancer has a vital role in the normal physiology of an organism. The genes that enable our brains and blood cells to develop are implicated in cancer. "

" Cancer has enormous diversity and behaves differently: it's highly mutable, the evolutionary principles are very complicated and often its capacity to be constantly mystifying comes as a big challenge. "

" I left Delhi in 1989 and remember very little of how life used to be then. Increasingly, in my recent visits to Delhi, I've started to realize that the city has become intellectually very lively. It makes me want to discover the city over and over again. "

Siddhartha Mukherjee

Life

Realize

" It turns out that the very genes that turn on in cancer cells perform vital functions in normal cells. In other words, the very genes that allow our embryos to grow or our brains to grow, our bodies to grow, if you mutate them, if you distort them, then you unleash cancer. "

" A breast cancer might turn out to have a close resemblance to a gastric cancer. And this kind of reorganization of cancer in terms of its internal genetic anatomy has really changed the way we treat and approach cancer in general. "

" Cancer is not just a dividing cell. It's a complex disease: It invades, it metastasizes, it evades the immune system. "

" Good physicians are rarely dispassionate. They agonize and self-doubt over patients. "

" There's a rising cancer trend and, as I said, one of the major contributors is the overall ageing of the population - we aren't dying of other things, so we're dying of cancer. "

" My memory of my household is of one immersed in books and music. I have a very intimate relationship with Bengali literature, particularly Tagore, and my interest besides reading then was music. "

" Unlike other diseases, the vulnerability to cancer lies in ourselves. We always thought of disease as exogenous, but research into cancer has turned that idea on its head - as long as we live, grow, age, there will be cancer. "

" If something is good, more is not necessarily better. Not always. "

Siddhartha Mukherjee

Better

Always

" Probably the most important reason we are seeing more cancers than before is because the population is ageing overall. And cancer is an age-related disease. "

" Writing anything as an expert is really poisonous to the writing process, because you lose the quality of discovery. "

" The gene that enables birds to learn songs can become cancer-causing. There is no normal physiological process that can't be bastardized by the disease. "