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" Pharmacology is benefited by the prepared mind. You need to know what you are looking for. "

Siddhartha Mukherjee

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" What we do in the laboratory is we try to design drugs that will not just eradicate cancer cells but will eradicate their homes. "

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" Cell culture is a little like gardening. You sit and you look at cells, and then you see something and say, 'You know, that doesn't look right'. "

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" Science is among the most profoundly human of our activities. Far from being subsumed by the dehumanising effects of technology, science, in fact, remains our last stand against it. "

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" If something is good, more is not necessarily better. Not always. "

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" I could write a thesis on the physiology of vision. But I had no way to look through the fabric of confabulation spun by a man with severe lung disease who was prescribed 'home oxygen', but gave a false address out of embarrassment because he had no 'home.' "

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" When you immerse yourself in medicine you realise that hope is not absolute. It's not that simple. "

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" I believe the biggest breakthroughs on cancer could come from brilliant researchers based in India. "

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" We now have poured in an enormous amount of resources into cancer. The National Cancer Institute Project, you know, runs about $5 billion a year. That's a large amount of money, but let's not be grandiose about the amount of money we're actually spending on a problem that is attacking us at the most fundamental level of the human species. "

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" I'm human, we all are - all doctors are - and grieving is a natural part of medicine. As a doctor, grieving is a natural part of medicine. If you deny that, again, you'd get into this trap of curing and victory. I think grief is very important. "

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" There is a duality in recognising what an incredible disease it is - in terms of its origin, that it emerges out of a normal cell. It's a reminder of what a wonderful thing a normal cell is. In a very cold, scientific sense, I think a cancer cell is a kind of biological marvel. "

Siddhartha Mukherjee

" Mary Lasker was an entrepreneur; she was a socialite. She was kind of a legendary networker. She became interested in saying, 'Well, you know, if these diseases don't have political support we'll never conquer them.' And she made, really, cancer her special cause. "

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" Nearly every one of the genes that turns out to be a key player in cancer has a vital role in the normal physiology of an organism. The genes that enable our brains and blood cells to develop are implicated in cancer. "

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" Each of us knows a few or several young people whose lives have been devastated by cancer. I don't mean to be nihilistic about it, but it is very much an active killer of people now. "

Siddhartha Mukherjee

" Cancer is not one disease but many diseases. "

Siddhartha Mukherjee

" One day, I had a patient who was going through chemotherapy who came to me and said, 'I'm going to go on with what I'm doing, but I need you to tell me what it is that I'm fighting.' "

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" Why did I write 'The Emperor of All Maladies?' A 56-year-old woman with an abdominal sarcoma, having undergone two remissions and a relapse, asked me to describe what she was battling. By the time I had finished answering her, I realised that I had written 600 pages. "

Siddhartha Mukherjee

" A strong intuition is much more powerful than a weal test. Normals teach us rules; outliers teach us laws. For every perfect medical experiment, there is a perfect human bias. "

Siddhartha Mukherjee

" Good physicians are rarely dispassionate. They agonize and self-doubt over patients. "

Siddhartha Mukherjee

" If you take 100 breast-cancer samples, 100 types of cancer have 100 different hallmarks of mutated genes. You could be nihilistic and say, 'Oh, God, we'll never be able to tackle this!' But there are deep, systematic, organizational principles at work in all that diversity. "

Siddhartha Mukherjee

" My memory of my household is of one immersed in books and music. I have a very intimate relationship with Bengali literature, particularly Tagore, and my interest besides reading then was music. "

Siddhartha Mukherjee

" There is a very moving and ancient connection between cancer and depression. "

Siddhartha Mukherjee

" We know cancer is caused ultimately via a link between the environment and genes. There are genes inside cells that tell cells to grow and the same genes tell cells to stop growing. When you deregulate these genes, you unleash cancer. Now, what disrupts these genes? Mutations. "

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" I think the cardinal rule of learning to write is learning to read first. I learned to write by learning to read. "

Siddhartha Mukherjee

" Probably the most important reason we are seeing more cancers than before is because the population is ageing overall. And cancer is an age-related disease. "

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" Writing anything as an expert is really poisonous to the writing process, because you lose the quality of discovery. "

Siddhartha Mukherjee

" Because I work on leukemia, the image of cancer I carry in my mind is that of blood. I imagine that doctors who work on breast cancer or pancreatic cancer have very different visualizations. "

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" Postwar U.S. was the world's leader in science and technology. The investment in science research was staggering. "

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" Unlike other diseases, the vulnerability to cancer lies in ourselves. We always thought of disease as exogenous, but research into cancer has turned that idea on its head - as long as we live, grow, age, there will be cancer. "

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" Cancer is not just a dividing cell. It's a complex disease: It invades, it metastasizes, it evades the immune system. "

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" Some cancers are curable, while others are highly incurable. The spectrum is enormous. Metastatic pancreatic cancer is a highly incurable disease, whereas some leukemia forms are very curable. There is a big difference between one form and another. "

Siddhartha Mukherjee