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" I think there is a basic comfort in clever people who know things. "

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" As a real person, he wouldn't last a minute, would he? But drama is about imperfection. And we've moved away from the aspirational hero. We got tired of it, it was dull. If I was House's friend, I would hate it. How he so resolutely refuses to be happy or take the kind-hearted road. But we don't always like morally good people, do we? "

" I didn't realize House would be the central character, more the bitter comic relief appearing occasionally. I relish his wounded nature - the lameness, the scarred Byronic hero. "

" I run six-to-eight miles a day, plus weights and aerobics in the lunch hour. I also lie a lot, which keeps me thin. "

" Lots of people would say House doesn't have any charm at all. I would disagree, though: I find him immensely charming and endlessly entertaining. He has a sort of grace and a wit about him, and ultimately, I think he is on the side of the angels. "

" I think actors are attracted to the idea of other identities and concealing themselves behind some other identity. "

" The first big stars, Bessie Smith, Ma Rainey, you know, these were gigantic stars. I even wonder sometimes whether all music actually comes from women, whether the first glimmering of music is a mother soothing a baby. "

" I don't really understand why everybody doesn't want to direct. It's an absolutely fascinating combination of skills required and puzzles set on every possible level, emotional and practical and technical. It calls upon such a wide variety of skills. I find it completely absorbing. "

" The glory of American television is Dennis Franz. "

" I think of House as a deeply moral character, though some would no doubt argue with me. He does not judge. Beyond his normal tetchiness, there were no more than a half-dozen moments of actual condemnation from him. He understood lies and also why you lied, and there was an absolution there that is very, very appealing. "

" Music is one of the noblest callings I can think of. It's the highest of all the art forms to me. For example, if my kid said to me, 'I want to give it all up,' whatever it is that they're doing, 'and I want to take my saxophone and go out,' I would say, 'May God go with you. This is a great and noble thing that you're doing.' "

" They're very harsh people, the British: hard to impress, very tough on each other, but I rather like that. It's not that the British are more honest - you're just under no illusion with them. "

" I get anxious about a lot of things, that's the trouble. I get anxious about everything. I just can't stop thinking about things all the time. And here's the really destructive part - it's always retrospective. I waste time thinking of what I should have said or done. "

" I think pain is a very - it's an extremely hard thing to empathize moment to moment. And you often don't remember your own pain, you know, that moment that you broke a limb or you burned yourself or, I think, this is a common thing that women talk about with childbirth, that the memory of the pain is hard to summon up and relive, thankfully. "

" I think good-looking people seldom make good television. And American television studios almost concede before they start: 'Well, it won't be good, but at least it'll be good-looking. We'll have nice-looking girls in tight shirts with F.B.I. badges and fit-looking guys with lots of hair gel vaulting over things.' "

" I hate menus, I hate choosing food. I just want to be brought. Bring me dinner! "

" Piano was - well, all musical instruments were taught in this very rigid, formal, classical method when I was young. "

" When the ship goes down, the waves very quickly roll over the top of it, and attention shifts elsewhere. It's just the natural order of things in TV - in life - and is as it should be. "

" The great trap for non-American actors trying to play Americans, I think, is to start thinking of American-ness as a characteristic. It isn't. It is no more a character trait than height. It is just a physical fact, and that's all there is to it. "

" When I was a small boy, 10, 11, 12, probably somewhere around there, when I first heard a blues song on the radio, it was a jolt of electricity. It grabbed me by the throat, it made me shiver. And I knew from that moment that this was for me and this would be with me for the rest of my life. "

" Acting is largely about putting on masks, and music is about removing them. "

" I feel like a hostage to fortune. Not that I am complaining. I wanted to play the role. But in truth I didn't think the show would be such a success. OK, I thought it would fail. Not because it was bad. I was confident it was good, but plenty of good things just sort of wither on the vine. "

" I admit I can't shake the idea that there is virtue in suffering, that there is a sort of psychic economy, whereby if you embrace success, happiness and comfort, these things have to be paid for. "

" I've never been clever with money. I will buy anything at the top of the market. "

" I never was someone who was at ease with happiness. "

" Pain is an event. It happens to you, and you deal with it in whatever way you can. "

" It alarms me to think of all that I have read and how little of it has stayed with me. "

" I think maybe even one of the reasons I became an actor was actually to hide. I mean, it sounds paradoxical because, of course, people are standing up in a public place and encouraging other people to look at them. So that's not the conventional definition of hiding. "

" People will survive, and they will find happiness. Happiness only comes when you're not looking for it. "

" I do actually like Los Angeles. Partly because I was told I wouldn't. "

" I personally believe that the iPod is a frankly corrosive device because it encourages you to surround yourself with your favorites. The whole idea of a playlist is to surround yourself with your favorite things, and the interesting thing is that when you do that, they cease to be your favorites. "

Surround Yourself