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" I do actually like Los Angeles. Partly because I was told I wouldn't. "

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" Lots of people would say House doesn't have any charm at all. I would disagree, though: I find him immensely charming and endlessly entertaining. He has a sort of grace and a wit about him, and ultimately, I think he is on the side of the angels. "

" I feel when acting, I am sometimes overly self-conscious; I think, 'Going, no, don't, put your eyebrow back where it was and, you know, turn to the left.' You know, I'm sort of very consciously adopting this character. But with music, I don't know. I found it was a question of just closing my eyes and just sort of letting things come out. "

" Some people are drawn naturally - there are natural guitarists, and there are natural piano players, and I think guitar implies travel, a sort of footloose gypsy existence. You grab your bag and you go to the next town. "

" I get anxious about a lot of things, that's the trouble. I get anxious about everything. I just can't stop thinking about things all the time. And here's the really destructive part - it's always retrospective. I waste time thinking of what I should have said or done. "

" I don't have a single complete show or movie or anything else that I could look at and say, 'Nailed that one.' But endless dissatisfaction is, I suppose, what gets us out of bed in the morning. "

" I think there is a basic comfort in clever people who know things. "

" I have my moments. Ever since I was a boy, I never was someone who was at ease with happiness. Too often I embrace introspection and self-doubt. I wish I could embrace the good things. "

" I wouldn't be able to act like Al Pacino or play the piano like Dr. John, But I could probably act better than Dr. John and play the piano better than Al Pacino. "

" The financing of all TV shows is dictated by finding an audience between 18 and 49. I have now passed beyond 49, so probably, I am no longer a desirable commodity for TV. And I am at peace with that; that's fine. "

" It alarms me to think of all that I have read and how little of it has stayed with me. "

" Clive Dunn, as I understand it, retired to the south of Spain, where he worked extensively in watercolours. I don't own any of Clive Dunn's watercolours. I loved him in 'Dad's Army,' loved him. But not enough to actually seek out his watercolour work. "

" I didn't realize House would be the central character, more the bitter comic relief appearing occasionally. I relish his wounded nature - the lameness, the scarred Byronic hero. "

" Directing is the best job going. I don't understand why everybody doesn't want to direct. It's an absolutely fascinating combination of skills required and puzzles set on every level - emotional and practical and technical. It calls up on such a wide variety of skills. I find it completely absorbing. I just love the whole process. "

" Driving a motorcycle is like flying. All your senses are alive. When I ride through Beverly Hills in the early morning, and all the sprinklers have turned off, the scents that wash over me are just heavenly. Being House is like flying, too. You're free of the gravity of what people think. "

" In film, because you know where the ending is, characters can change, but in television, you substitute revelation for change, and that can be hard to pull off. "

" My dad gave me my first bike at 16. I soon fell off and was in a wheelchair for weeks. I haven't fallen since. "

" I'm reasonably easygoing. Messing up my lines or making a fool of myself is where you find my fears. Like a lot of English people, I'm prey to embarrassment - the dread that everyone's sort of sniggering at you, that you're going to look like an idiot. I think that sort of halts us all. "

" I don't talk like House, or walk like him. I certainly don't think like him. I don't like to think for more than 15 minutes at a stretch actually; I am a fragile flower. "

" Riding my motorcycle around L.A. is like my own video game. But unlike many folks at the wheel, I am occupied with getting where I'm going and keeping myself safe. Most people are applying makeup, texting, and checking out the beauty in the next car. "

" I couldn't imagine what Fox thought they were doing, contemplating such a jagged protagonist for a prime-time drama. I only knew that I wanted the role very much. "

" Music is one of the noblest callings I can think of. It's the highest of all the art forms to me. For example, if my kid said to me, 'I want to give it all up,' whatever it is that they're doing, 'and I want to take my saxophone and go out,' I would say, 'May God go with you. This is a great and noble thing that you're doing.' "

" I am a coffee fanatic. Once you go to proper coffee, you can't go back. You cannot go back. "

" The glory of American television is Dennis Franz. "

" I don't think of myself as funny. I think of myself as rather grave, actually. And I'm suspicious of fun. I never quite know what that is or how to deal with it or how to generate it. That's my fault. I know it's a burden on the people I'm with. It's tiresome. "

" I've never been clever with money. I will buy anything at the top of the market. "

" To be able to pretend to be something that I'm frankly not is very liberating and exciting. "

" Girls are complicated. The instruction manual that comes with girls is 800 pages, with chapters 14, 19, 26 and 32 missing, and it's badly translated, hard to figure out. "

" I think good-looking people seldom make good television. And American television studios almost concede before they start: 'Well, it won't be good, but at least it'll be good-looking. We'll have nice-looking girls in tight shirts with F.B.I. badges and fit-looking guys with lots of hair gel vaulting over things.' "

" I think pain is a very - it's an extremely hard thing to empathize moment to moment. And you often don't remember your own pain, you know, that moment that you broke a limb or you burned yourself or, I think, this is a common thing that women talk about with childbirth, that the memory of the pain is hard to summon up and relive, thankfully. "

" I never was someone who was at ease with happiness. "