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" I'm not sure sometimes if it was because Will was gay or it was a sitcom. But that combination does make it hard to become the new lead on the 'Sopranos.' "

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" I always kind of dreamed locally - I never really ever dream that I would be south of the border; I dreamed about being a theatre star in Toronto, and maybe I'd do Stratford and regional stuff. I always thought it would be a slow growth. "

" I never felt cool growing up. I was a bit of an outsider, but I discovered theatre very early on, which got me through. "

" I think I was very lucky that I didn't get well-known until my early thirties. If it had happened when I was younger, you might have seen me falling out of nightclubs. I think I conducted myself as a much better human being because I was already married when all that came along (I got married five months after I got the role as Will). "

" Probably one of the most surreal moments of my career was acting in front of Notre Dame with a mime. "

" We didn't, with 'Will & Grace,' set out to change the gay world. We just set out to be funny. "

" At home in L.A., Sunday is lazy. It's the wife and me lying in bed with coffee, watching 'The Soup' or something funny on TiVo. The kid will occasionally join us. Eventually, breakfast is at a place down the street called Paty's. And we always have some kind of great dinner - my wife makes a great roast beef. "

" I know where TNT's sweet spot is, and when I read 'Perception,' I thought, 'This is a chance to play a fascinating, fun, challenging character but still within the realm of something that will sit very well with 'The Closer' and 'Major Crimes' and the other shows there.' "

" I'm an actor. I can't afford to have a type. I love to mix it up. "

" There wasn't an episode of 'Will & Grace' that didn't begin with my voice saying, 'Will & Grace' is taped before a live studio audience. "

" I have accomplished a lot, but it didn't happen overnight for me. I was 35 when I got the show, and had been working professionally for 15 years. It would be a lot weirder if I were in my early 20s and stumbled into it. "

" If you can last long enough, in success, you have to get really creative and come up with new stuff. "

" I saw 'Othello' with Christopher Plummer and James Earl Jones. "

" Mental illness is the last frontier. The gay thing is part of everyday life now on a show like 'Modern Family,' but mental illness is still full of stigma. Maybe it is time for that to change. "

" The vote is the important thing. Just go and vote. "

" You can write your own history. "

" We see people talking to themselves all the time. We always have. Particularly if they're homeless people or at all questionable, there's a sense of, 'That guy's crazy!' I see that now with a much more empathetic eye. "

" In the future, things will truncate! No, in the age of Twitter, we can't be upset when words become shorter. "

" Shelter dogs should be adopted into loving homes, not used in cruel experiments. That's why I support the Cruelty Free International global dog campaign. "

" I hope that dog lovers around the world will support the Cruelty Free International global campaign to end the use of dogs in outdated and cruel experiments. "

" When I was 16, I'd ping pong between AC/DC and Barry Manilow without any sense of irony. "

" Back when I was in theater school, trying to figure out what I was going to do with my life, 'Sweeney Todd' was a huge touchstone for me, my favorite musical for sure. "

" I think we all realize that anyone can - and has - gotten AIDS. So there's obviously still a lot to be done. "

" It's very, very hard to create something that is big these days because you have niche markets - and, you don't necessarily need to be big; the show is specifically created for a small group of people. You know, if it's on the USA network, well, then a small group of people is fine. "

" This 'historical record' will exist, flawed as it is, in hundreds of years. What will that tell the future? How accurate are we reporting our lives? "

" That was the only trepidation I had about 'Will & Grace.' It had nothing to do with the sexuality of the character. It was more, 'This could be the next 7 to 10 years of my life.' "

" As I got older, I realized that my life experience, what I really had, was always going to be more valuable than what I pretended to have. "

" Will Truman will be on my epitaph, but as an actor, I have to challenge myself. "

" Every day, there's something that makes you go, 'Is this Funny or Die?' That can't be a real headline. "

" That's the hard part of television: When you walk into the network tests, you're signing away seven years of your life. "

" I find that with every script I get, I go, 'Who knew this? This is so cool!' "