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" Lithium prevents my seductive but disastrous highs, diminishes my depressions, clears out the wool and webbing from my disordered thinking, slows me down, gentles me out, keeps me from ruining my career and relationships, keeps me out of a hospital, alive, and makes psychotherapy possible. "

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" An intense temperament has convinced me to teach not only from books but from what I have learned from experience. So I try to impress upon young doctors and graduate students that tumultuousness, if coupled to discipline and a cool mind, is not such a bad sort of thing. "

Kay Redfield Jamison

Mind

Cool

Discipline

" It is important to value intellect and discipline, of course, but it is also important to recognize the power of irrationality, enthusiasm and vast energy. "

" Several politicians and wives of politicians have been public about their experiences with depression or bipolar illness, including Lawton Chiles, Patrick Kennedy, Tipper Gore and Kitty Dukakis. Each made a tremendous difference by doing so. "

" I have had manic-depressive illness, also known as bipolar disorder, since I was 18 years old. It is an illness that ensures that those who have it will experience a frightening, chaotic and emotional ride. It is not a gentle or easy disease. "

" Confidentiality is an ancient and well-warranted social value. "

" People respond differently to people who are grieving. They reach out. But depression is so very isolating. It's hard to explain to anyone who has never been depressed how isolating it is. Grief comes and goes, but depression is unremitting. "

" I say I'm an academic: a professor of psychiatry at Johns Hopkins. And I write. "

" Mood disorders are terribly painful illnesses, and they are isolating illnesses. And they make people feel terrible about themselves when, in fact, they can be treated. "

" Grief is so human, and it hits everyone at one point or another, at least, in their lives. If you love, you will grieve, and that's just given. "

" Nothing good comes out of depression. "

" There are scientists all around the world looking for the genes responsible for bipolar illness and major depression. "

" Grief comes and goes, but depression is unremitting. "

" A possible link between 'madness' and genius is one of the oldest and most persistent of cultural notions. "

" I believe that curiosity, wonder and passion are defining qualities of imaginative minds and great teachers; that restlessness and discontent are vital things; and that intense experience and suffering instruct us in ways that less intense emotions can never do. "

" Mania is as bad as it gets. If not treated, it will become worse, more frequent, and harder to treat. "

" It is an odd thing, owing life to pills, one's own quirks and tenacities, and this unique, strange, and ultimately profound relationship called psychotherapy. "

" No pill can help me deal with the problem of not wanting to take pills; likewise, no amount of psychotherapy alone can prevent my manias and depressions. I need both. "

" It's more common than not that bipolar illness will start in the teens. One of the reasons I spend a lot of time on college campuses is exactly that reason. It's terribly important to talk to students about knowing these things in advance. "

" With grief, you have reason to despair; it's a human thing. "

" Psychologists, for reasons of clinical necessity or vagaries of temperament, have chosen to dissect and catalog the morbid emotions - depression, anger, anxiety - and to leave largely unexamined the more vital, positive ones. "

" Lithium remains the gold standard, but many drugs now treat bipolar disorder. Medication is critical and should be combined with psychotherapy. Compliance is a major problem. Patients believe that once they're better, they no longer need the medication. It doesn't work that way. "

" People talk about grief as if it's kind of an unremittingly awful thing, and it is. It is painful, but it's a very, very interesting sort of thing to go through, and it really helps you out. At the end of the day, it gets you through because you have to reform your relationship, and you have to figure out a way of getting to the future. "

" Scientists have made extraordinary advances in understanding the brain and its disorders. "

" I love animals, and I was always attracted to the idea of being a zoo veterinarian or a veterinarian with the circus. "

" In some cases, some people do get depressed in the middle of their grief, and they really need to be treated for depression. "

" Because I teach and write about depression and bipolar illness, I am often asked what is the most important factor in treating bipolar disorder. My answer is competence. Empathy is important, but competence is essential. "

" Moods are complicated and very much a part of who we are. People would be very boring without them. "

" One of things so bad about depression and bipolar disorder is that if you don't have prior awareness, you don't have any idea what hit you. "

" I think one thing is that anybody who's had to contend with mental illness - whether it's depression, bipolar illness or severe anxiety, whatever - actually has a fair amount of resilience in the sense that they've had to deal with suffering already, personal suffering. "

" There is no common standard for education about diagnosis. Distinguishing between bipolar depression and major depressive disorder, for example, can be difficult, and mistakes are common. Misdiagnosis can be lethal. Medications that work well for some forms of depression induce agitation in others. "