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" Scientists are not these guys in lab coats deep in the inner bowels of universities and hospitals with their Bunsen burners. They're the people molding the culture that we live in, the future of our culture, and the technology we rely on every day. These are the rock stars of our time right now. "

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" It took me a long time to realize that to walk around without a certain amount of belief in myself, to walk onto a job with my tail between my legs, wasn't behooving anyone else. "

Johnny Galecki

Walk

Long

" Perhaps 'Big Bang' fans feel so protective of the show because it is, despite being a hit show on a big network, something of a word-of-mouth phenomenon. "

" I know a lot of incredibly, profoundly talented, skilled people that aren't given certain opportunities or any opportunities, and that aren't working. "

" I love to work. I absolutely love to work. "

" I used to know Jennifer Love Hewitt. We lived in the same apartment building when I was about... jeez, I guess it was when I was doing 'Christmas Vacation', so I was about 13 or 14. "

" I watch '60 Minutes' and 'Dateline' and '20/20.' I work in fantasy all day, so when I go home I want to touch reality. "

" It's that one thing that you're passionate about, that you end up developing tunnel vision for and everything else tends to fall by the wayside. Passion is appealing and universal. "

" When I started on 'Roseanne,' it was a great achievement for me at the time. But I wasn't a part of building it; I wasn't a carpenter in creating that juggernaut. "

" I'm still a Chicagoan in the fact that I can't do Christmas with sand and palm trees. It just doesn't compute - it's not Christmas unless your face hurts when you step outside. "

" 'Entourage' is a great show, but it's fantasy. I spent my twenties in L.A. in this business, and my life didn't look anything like that. 'Big Bang' reflects a side of men that is rarely shown. We see their flaws - all of them. "

" You can't really claim too much ownership of your character. They really do belong to the writers, and in many ways, you're just their puppet. "

" We didn't have a TV because we didn't have a whole lot of money. My parents would have their friends over - their friends who thought, 'How can you live without a TV?' "

" I'm not at all competitive. I'd rather play Solitaire than ping-pong. "

" As they say, there are two rules in improv: Never say no, and never ask why. When another actor asks 'Why?' or says no to something you're suggesting, then it's very clear that they're putting the onus on you, because they're not comfortable with it themselves. "

" There is that stereotype of a nerd with the high pants and pocket protector and that kind of thing. That can sustain comedy for maybe a movie - hence the 'Revenge of the Nerds' franchise - but not for hopefully years on the air. It's a sight gag, not a story. "

" Comedy is similar to hockey... in only one way. You get a lot of credit for assists. So I try to serve whatever the intention is, be it the joke or the story or the scene or the moment or the kiss, even if it's not my joke or moment. "

" When you read the news, and you see all this bad stuff happening, there's a tendency to lose faith in humanity. But I meet so many people who restore it and realize that, actually, 99 percent of people are great. "

" When I'm back home in Chicago, since 'Roseanne' was such a Midwestern, blue-collar show, that's what sticks out in people's minds. "

" I work in fantasy all day, so when I go home, I want to touch reality. "

" Right now, I'm very healthy. I have no vices left. Except sugary breakfast cereal. And absinthe, of course. "

" People are complicated; you put two of them together and it's generally a mess, but hopefully a beautiful mess. "

" It's never been a priority for me to concentrate on the likability of the character. "

Johnny Galecki

Priority

Character

" Theater audiences don't pull punches. They'll let you know when they're feeling ripped off. "

" Growing up in Chicago, I was a theater nerd. That might be very cool on the East Coast, but in Chicago, it's really the athletes that come in No. 1 on the cool scale. Maybe musicians after that. Community theater? That's way down the list, my friend. "

" In a series, you really need to stay open-minded. It's not like a play or a film, where you can create and fully commit to your character's back-story. "

" You know, I read the papers and I watch the news a lot. I watch 'Dateline' and '48 Hours'. And I think we have a tendency to become terrified of one another, thinking that there is a serial killer that is on either side of you. "

" It's always interesting for me to watch the pilot of an established show because you see how the writers and actors weren't really sure what the show was and what the dynamics were. If you look at the pilot for 'Seinfeld,' for example, it's practically unrecognizable. "

Johnny Galecki

Interesting

You

" You get to a certain point - gratefully - when you're out of your twenties, and you realize how fleeting life is. So, it becomes important to feel as if the people in your life know exactly how you feel about them at all times. "

" We can't really do any improv on 'The Big Bang' because we don't understand a lot of what the dialogue means to begin with, because of the physics jargon. "

" When I grew up, scientists were anti-social people who worked in basements and wore coats and worked with bunson burners, and now they're in our technology every day, and our technology has almost become fashion accessories. "