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" The first thing that I ever made was a documentary that I shot... in downtown L.A. about a group of homeless people. "

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" 'Roseanne' was massive for me. I adored that show. I mean, the show was this couple who weren't cookie-cutter, and they were sexy, and we know that they like to have sex with each other, and they flirted, and then they ragged on their kids, and their kids ragged on them, and it was such a realistic depiction. "

" I don't think I have a demographic. I was at Comic-Con in San Diego recently, and I was doing a signing, and my line was all military guys, young girls, housewives and guys in wheelchairs. There was just everybody all over the place. "

" Sometimes when I'm in the editing room and there's a new person there, like a music editor or a post person that I don't really know, I'm like, 'Oh, you shouldn't be in here. This is too personal - you can't watch this.' But then I'm like, hey dummy, you're about to show this to the whole world. "

" When I saw 'Louie' and 'Girls', I was blown out of the water. They were fearless portrayals of real life. Everyone has a different experience. "

" I like people to have their own reaction and their own take on things. And I don't like to shove my - what I want them to feel or think - down their throats. I like people to say, 'What was that about?' or 'Why did that happen?' And so, any reactions are welcome. "

" Literally, FX is like, 'How can we foster your vision?' My vision is pretty much taking pictures of the way I see my life. "

" It's spelled, like, S-E-R-G. I always thought it would be funny if I called my son 'Sir.' Like calling your daughter 'Ma'am,' or something like that. "

" It's a hilarious part of my past, all the sitcoms I did in the '80s. And then all the animation - animation is amazing. It's really been great. "

" I've been adapting ever since my oldest had her first play date with a boy, and I was like, 'That's not normal,' because I came from the old school. Now boys sleep over at my house. It doesn't matter which girl, which age. "

" They would call me 'The Cleaner' because I would replace boys who were real adolescents, and their voices completely changed, and they couldn't do the voices anymore. "

" One of the things I learned in animation is that you never, ever want to start doing a voice that you can't sustain for four straight hours. "

" I'm more of somebody who'll bend over backwards for people and, you know, wait at the back of the line until everybody's taken care of. That's really my nature. "

" Everything that happens to me in a day enhances my parenting. "

" I try to direct myself the way I direct the other actors who come on my show. "

" Before 'Lucky Louie,' nobody would ever cast me to play a mom or a wife; nobody ever saw me in that role, which is weird, since that's who I really am. "

" I am a single mom of three girls, and I'm getting through that. If I can get through that, I can direct a whole season of television that I star in. "

" The only people on this planet that can make me feel like my feelings are hurt are my kids. "

" The thing about women playing boys is that we're not going to age, and we're not going to go through puberty in the middle of a long-running series. "

" I don't usually say 'working mom' because I think all moms are working moms. I feel like that diminishes moms. People should say 'working dad' as opposed to working moms. "

" There's something in my voice tonally that's like a boy, so I started being able to do boy voices and to be known as having a naturalistic boy tone without pushing it. "

" Being a mother is the ultimate training ground for anything. "

" I'm somebody who, if I went to the grocery store, and one of them wasn't with me, I would feel guilty. I would be like, 'I shouldn't be doing anything without them, anytime, ever.' A very codependent way of thinking. Also, motherhood is hugely about guilt. "

" I love that, 'mommy-shaming.' When I was a new mom, I was obsessed with how I was being perceived and trying to fit in as a mom, going to mommy-and-me classes and things like that, and never quite measuring up to 'the real moms,' the 'robot moms,' as I called them. "

" I learned so much from my life as an actor, as a kid actor through being an adult actor, and then becoming a writer and producer and doing animation. "

" Sometimes when I'm in the car driving, I scream at the top of my lungs. "

" My roles in the '80s were, like, gender dysphoric. I wasn't pretty, I wasn't this, I wasn't that. And I am kind of butchy, you know. That's just my thing. "

" My life is extraordinary because it's so normal, but it's so 'extra' for some reason. "

" I learned so much from the writing on 'King of the Hill', which I thought was just magnificent. They would let real moments happen in this animated, one-dimensional world. I feel like I've been in school this whole time. "

" Wouldn't it be funny if I were a total nightmare? If I just shot 21-hour days and went over budget? But, you know, it's something I'm really careful about, because I am a mom, and also, I'm an actor. I'm a pleaser: I don't want to take up too much of people's time. "

" I want to be a strong, safe mom who my kids also want to be around. "