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" The resistance to science is idiotic. "

Seth MacFarlane

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" Science has become politicized, and that's an embarrassment. "

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" The trend today is vampires, zombies, angels, all the stuff that puts me right to sleep. It's too bad because it's so much less interesting than the diversity of stories you can tell with science. "

Seth MacFarlane

" The problem with the cable networks is the lack of money, not from personal income but as far as show budget. "

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" I'm sure there are close calls that we're not even aware of hundreds of times a year. You cross the street, and if you'd crossed the street two minutes later, you'd have been hit by a car, but you'd never know it. I'm sure that kind of stuff happens all the time. "

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" The only problem is time. "

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" I did a lot of theater when I was in high school and college. I also did stand-up in college, so it was always part of what I did. "

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" With any half-hour comedy, it kind of takes on its own life and finds itself. "

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" I can't believe I am hosting the Oscars. It's an honor everyone else said no. "

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" The success of 'The Simpsons' really opened doors. It showed that if you were working in animation you didn't necessarily have to be working in kids' television. "

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" I'm bad at golf. "

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" Obviously I'm a big fan of 'South Park', but it gets tiring at times when there's so much of it. "

Seth MacFarlane

" The good thing about Broadway is that you don't have to worry about an airdate. It gets done when it gets done. "

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" What makes me happy is just keeping my brain challenged and stimulated and on its toes. "

Seth MacFarlane

" 'American Dad' is, by its nature, much more political. "

Seth MacFarlane

" There have to be people who are vocal about the advancement of knowledge over faith. "

Seth MacFarlane

" If something sticks around long enough that it makes it to seasonal D.V.D. release, I'll watch it. That's how I watched 'The Sopranos'. "

Seth MacFarlane

" I think at times I read too much of my own press. I wish I was better at taking in how great my life is, but that's surprisingly elusive. I tend to be very hard on myself and insecure about failing no matter what happens. "

Seth MacFarlane

" You don't want to be nasty for the sake of being nasty. "

Seth MacFarlane

" I always thought it would be funny to have the Parents Television Council write an episode of 'Family Guy' and give them full creative control. Then see how good the episode is. That's something we've actually discussed in the writers' room. We haven't proposed it yet, but if somebody from the PTC reads this, it might be worth discussing. "

Seth MacFarlane

" Every year, the Friday before the new Saturday-morning shows would premiere, the networks would do this big preview special, and I was always glued to the TV. As horrible as they were, they were entertaining at the time. There was a lot of showmanship from the networks based around the new lineup. "

Seth MacFarlane

" When 'Family Guy' started, we wanted to make it more like a sitcom. And there was very little music. "

Seth MacFarlane

" The worst thing to happen at the Oscars would be if nothing happened. You want something unscripted, something to riff on, something kinda out there. "

Seth MacFarlane

" I'll tell you what I think is not okay. Have you ever seen that show on MSNBC, 'Lockup?' It's a reality show that takes place inside a prison. Do the prisoners have to sign release forms? Or do they have to be on it whether they like it or not? "

Seth MacFarlane

" Everybody in my family had a real sick, twisted sense of humor. Most of the jokes we make in our house, we would just never even dream of making anywhere else. Just sick, horrible stuff. That wasn't anything new to college. "

Seth MacFarlane

" I have a car that I like - an Aston Martin - for Sunday drives in the country. "

Seth MacFarlane

" The quest for Tommy Lee Jones' laugh begins now. "

Seth MacFarlane

" I was about two years old when I first started drawing recognizable characters. "

Seth MacFarlane

" On a certain day, I will tweet five times, and then I'll go four days without tweeting at all. It really depends on what time allows. Twitter, priority-wise, has to come after the work is done. "

Seth MacFarlane

" When you are in a room and your job is to write jokes 10 hours a day, your mind starts going to strange places. "

Seth MacFarlane

" I was a film major with a concentration in animation. "

Seth MacFarlane