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" When you are in a room and your job is to write jokes 10 hours a day, your mind starts going to strange places. "

Seth MacFarlane

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" I'm big on the importance of science, particularly right now at this point in time when there's sort of a systematic rejection of science by a lot of people in America. "

Seth MacFarlane

" Every year, the Friday before the new Saturday-morning shows would premiere, the networks would do this big preview special, and I was always glued to the TV. As horrible as they were, they were entertaining at the time. There was a lot of showmanship from the networks based around the new lineup. "

Seth MacFarlane

" If I were to do a musical, I think I would rather make a film musical. "

Seth MacFarlane

" The Simpsons are ugly-looking, and they should be. That's what works. That's one of the things that's funny. "

Seth MacFarlane

" I cannot tell good art from bad art. I have no eye for it. "

Seth MacFarlane

" The worst thing to happen at the Oscars would be if nothing happened. You want something unscripted, something to riff on, something kinda out there. "

Seth MacFarlane

" I'm sure there are close calls that we're not even aware of hundreds of times a year. You cross the street, and if you'd crossed the street two minutes later, you'd have been hit by a car, but you'd never know it. I'm sure that kind of stuff happens all the time. "

Seth MacFarlane

" I was a huge 'Star Trek' fan. I loved the 'Twilight Zone' growing up. In the future, I hope to create some thoughtful, sci-fi drama. "

Seth MacFarlane

" There was no joke I could make that was too offensive. I can actually remember at least one time where my mother told me something that, I was like, 'whoa!' "

Seth MacFarlane

" I had - I was pretty hell bent on getting into the cartoon business specifically as an artist from the get-go. "

Seth MacFarlane

" Everybody in my family had a real sick, twisted sense of humor. Most of the jokes we make in our house, we would just never even dream of making anywhere else. Just sick, horrible stuff. That wasn't anything new to college. "

Seth MacFarlane

" I'm bad at golf. "

Seth MacFarlane

" Obviously I'm a big fan of 'South Park', but it gets tiring at times when there's so much of it. "

Seth MacFarlane

" The trend today is vampires, zombies, angels, all the stuff that puts me right to sleep. It's too bad because it's so much less interesting than the diversity of stories you can tell with science. "

Seth MacFarlane

" What makes me happy is just keeping my brain challenged and stimulated and on its toes. "

Seth MacFarlane

" I did a lot of theater when I was in high school and college. I also did stand-up in college, so it was always part of what I did. "

Seth MacFarlane

" On a certain day, I will tweet five times, and then I'll go four days without tweeting at all. It really depends on what time allows. Twitter, priority-wise, has to come after the work is done. "

Seth MacFarlane

" You would not want me on your football team. "

Seth MacFarlane

" I still do a lot of drawing on a daily basis. "

Seth MacFarlane

" The problem with the cable networks is the lack of money, not from personal income but as far as show budget. "

Seth MacFarlane

" I wrote on a show called Johnny Bravo when I was at Hanna-Barbera. "

Seth MacFarlane

" The only problem is time. "

Seth MacFarlane

" Believe it or not, I have about the same success rate as anyone else. Sometimes you hit, sometimes you miss. "

Seth MacFarlane

" The resistance to science is idiotic. "

Seth MacFarlane

" I'm from Connecticut, and we don't have any dialects. Well, I don't think we have any dialects, and yeah, it's very complex. That Rhode Island/Massachusetts New England region is arguably the hardest dialect to nail. "

Seth MacFarlane

" You gotta keep the funny intact. "

Seth MacFarlane

" The good thing about Broadway is that you don't have to worry about an airdate. It gets done when it gets done. "

Seth MacFarlane

" There have to be people who are vocal about the advancement of knowledge over faith. "

Seth MacFarlane

" People do that on Facebook and it's the dumbest thing in the world. I don't care what your dinner looks like. Stop cluttering up the Internet with pictures of your dinner. "

Seth MacFarlane

" When 'Family Guy' started, we wanted to make it more like a sitcom. And there was very little music. "

Seth MacFarlane