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" There have to be people who are vocal about the advancement of knowledge over faith. "

Seth MacFarlane

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" I'm big on the importance of science, particularly right now at this point in time when there's sort of a systematic rejection of science by a lot of people in America. "

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" If I were to do a musical, I think I would rather make a film musical. "

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" Fox is notorious for having a very thick skin about taking shots at themselves. "

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" I can't believe I am hosting the Oscars. It's an honor everyone else said no. "

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" We never really tried to shock for shock's sake on 'Family Guy'. If something was horribly offensive and shocking, we would put it in if it was also hysterically funny. "

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" I did a lot of theater when I was in high school and college. I also did stand-up in college, so it was always part of what I did. "

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" The worst thing to happen at the Oscars would be if nothing happened. You want something unscripted, something to riff on, something kinda out there. "

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" Evolution doesn't care whether you believe in it or not, no more than gravity does. I want to rekindle excitement over what we've achieved as a species with the space program. We can't afford to regress back to the days of superstition. "

Seth MacFarlane

" I'll tell you what I think is not okay. Have you ever seen that show on MSNBC, 'Lockup?' It's a reality show that takes place inside a prison. Do the prisoners have to sign release forms? Or do they have to be on it whether they like it or not? "

Seth MacFarlane

" Some of those more out-there jokes were written in the wee hours of the morning. Somehow, they remained funny the next day. "

Seth MacFarlane

" I'm sure there are close calls that we're not even aware of hundreds of times a year. You cross the street, and if you'd crossed the street two minutes later, you'd have been hit by a car, but you'd never know it. I'm sure that kind of stuff happens all the time. "

Seth MacFarlane

" I always thought it would be funny to have the Parents Television Council write an episode of 'Family Guy' and give them full creative control. Then see how good the episode is. That's something we've actually discussed in the writers' room. We haven't proposed it yet, but if somebody from the PTC reads this, it might be worth discussing. "

Seth MacFarlane

" Obviously I'm a big fan of 'South Park', but it gets tiring at times when there's so much of it. "

Seth MacFarlane

" The Simpsons are ugly-looking, and they should be. That's what works. That's one of the things that's funny. "

Seth MacFarlane

" The way Disney characters move, they're very kind of slow and fluid and flowing; one pose kind of eases into the next. If you look at a show like 'The Simpsons' and subsequently a show like 'Family Guy' - the characters will jerk from pose to pose a lot, a bit more snappy. Which sort of goes along with the writing tone of the show. "

Seth MacFarlane

" If a song is funny and absurd, and it sounds great, it's just going to be that much funnier. And there's no better example of that than 'Monty Python.' "

Seth MacFarlane

" The resistance to science is idiotic. "

Seth MacFarlane

" On a certain day, I will tweet five times, and then I'll go four days without tweeting at all. It really depends on what time allows. Twitter, priority-wise, has to come after the work is done. "

Seth MacFarlane

" With any half-hour comedy, it kind of takes on its own life and finds itself. "

Seth MacFarlane

" I love the English. My God, they brought us 'Benny Hill,' 'Monty Python,' 'The Office,' Neville Chamberlain. "

Seth MacFarlane

" 'American Dad' is, by its nature, much more political. "

Seth MacFarlane

" There was no joke I could make that was too offensive. I can actually remember at least one time where my mother told me something that, I was like, 'whoa!' "

Seth MacFarlane

" I'm from Connecticut, and we don't have any dialects. Well, I don't think we have any dialects, and yeah, it's very complex. That Rhode Island/Massachusetts New England region is arguably the hardest dialect to nail. "

Seth MacFarlane

" I had - I was pretty hell bent on getting into the cartoon business specifically as an artist from the get-go. "

Seth MacFarlane

" The quest for Tommy Lee Jones' laugh begins now. "

Seth MacFarlane

" If something is shocking without being funny it's hard to justify. "

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" The success of 'The Simpsons' really opened doors. It showed that if you were working in animation you didn't necessarily have to be working in kids' television. "

Seth MacFarlane

" I was about two years old when I first started drawing recognizable characters. "

Seth MacFarlane

" At one point, I was hell-bent on being a Disney animator, and sort of got over that in college and wanted to do my own stuff. You know, towards the end of college I had actually planned to go to the Boston Conservatory of Music for musical theater. "

Seth MacFarlane

" The trend today is vampires, zombies, angels, all the stuff that puts me right to sleep. It's too bad because it's so much less interesting than the diversity of stories you can tell with science. "

Seth MacFarlane