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" Whilst worthy in themselves, applications shouldn't be the only way to drive basic research. "

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" In order to protect the market value of a proprietary database, the owner must prohibit redistribution of the contents - otherwise, the information would quickly leak out and be widely known. "

" The currencies of science are discoveries and ideas; the rewards are the excitement of going where nobody has been before and, if one is inclined to such things, the kudos of peer acclaim, plus funds to do more research. "

" You have to say - and I do - that anything that blocks that cheapest possible point-of-care delivery of health is wrong. "

" Science and the many benefits that science has produced have played a crucial part in our history and produced vast improvements to human welfare. "

" Muriel, my mother, was my main confidant. She was a teacher of English at Watford grammar school but took a break while my sister Madeleine and I were children. She held court in the kitchen, and we talked about everything. "

" The strong evidence is that we're running out of space. We're collectively affecting the world's climate. This is due to the still-growing human population and our increase in consumption. "

" Many people thought that, given my knowledge of the egg, I should analyse embryonic mutants. "

" It is very clear that the present system of innovation for medicines is very inefficient and really somewhat corrupt. It benefits shareholders over patients; it produces for the rich markets and not for the poor and does not produce for minority diseases. "

" An awful lot of food is thrown away. This you can call a spillover. It doesn't sort of enter into our economic system because it's a consequence of running things in a highly competitive way: the free market, global pricing and so on. "

" The free market is the epitome of life itself. This is something that all scientists recognise because science itself operates on free market lines. "

" Title deeds establish and protect ownership of our houses, while security of property is as important to the proprietors of Tesco and Sainsbury's as it is to their customers. "

" In science, as in business, there must be structures that ensure the well endowed do not use their position to block competition. "

" What is the purpose of being human and alive without doing new things? "

" On my mother's side, I come from Midlands engineers and, on my father's, from tenant farmers near Oxford. "

" Our work on C. elegans emphasized the benefits of sharing large amounts of information. We took a global approach to discover the mechanisms that led to the development of the worm. "

" The fact is that proprietary databases don't work for such basic and broadly needed information as the sequence of the human genome. "

" I don't want a few extra weeks of life at enormous cost, for example, when it comes to the end. "

" The myth is that IP rights are as important as our rights in castles, cars, and corn oil. IP is supposedly intended to encourage inventors and the investment needed to bring their products to the clinic and marketplace. "

" I wandered along to the chemistry labs, more or less on the rebound, and asked about becoming a research student. It was the '60s, a time of university expansion: the doors were open, and a 2:1 was good enough to get me in. "

" We knew that all the protein-coding bits of genes do is to produce protein - they have to have instructions to turn them on and off. Those sequences lie well outside the protein-coding sequences, sometimes thousands, tens of thousands of bases away. "

" When it came to choice of subjects, science was obvious - since I was uninterested in anything else - but a decision that caused consternation in some eyes was my demand to take biology for A-level. "

" We can choose to address the twin issues of population and consumption to rebalance the use of resources to a more egalitarian pattern of consumption. "

" It is not a Pandora's box that science opens; it is, rather, a treasure chest. We, humanity, can choose whether or not to take out the discoveries and use them, and for what purpose. "

" When results are shared freely amongst the biological community, as has been done for the worm and the Human Genome Projects, specialist scientists can move much more rapidly towards their goals. "

" I believe our basic information, our 'software', should be free and open for everyone to play with, to compete with, to try and make products from. I do not believe it should be under the control of one person. "

" If we understand the worm, we understand life. "

" As far back as I remember, and earlier, I was an artisan, a maker and doer. Mechanically minded, my parents said. "

" The only thing I have retained from my upbringing - I did not retain the religious element - is the idea that you do not do things for money. "

" Biomedical research is only as good as its delivery. Distribution of medicines by charities is no more than a stopgap. "

" It was a matter of not living lavishly but enjoying what you had, growing things with your hands, working hard, but not being tied to a nine-to-five job, and generally feeling that there's more to life than money. "