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" I needed to start pulling at this other sort of funnier, lighter side. So I auditioned for everything. I auditioned for 'Friends,' even. "

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" 'Monk''s gone, and 'House' is gone. Maybe I can pick up where they left off. "

" If we're karaoke-ing, I'm as likely to do Aerosmith as I am 'Sweeney Todd'. "

" I think we all realize that anyone can - and has - gotten AIDS. So there's obviously still a lot to be done. "

" I hope that dog lovers around the world will support the Cruelty Free International global campaign to end the use of dogs in outdated and cruel experiments. "

" I feel like 'Travelers' is something I can legitimately say, 'You're going to love this.' I think then people will accept me as a different thing. And if they don't, it's fun trying. "

" Not a big sci-fi guy. "

" Each one of us fulfills a piece of a larger puzzle. "

" Will isn't a screaming queen - that's Jack's part. They needed someone to play the part for America. It's just not the same as Britain. To have a gay character as a lead is risky. "

" Mental illness is the last frontier. The gay thing is part of everyday life now on a show like 'Modern Family,' but mental illness is still full of stigma. Maybe it is time for that to change. "

" Probably one of the most surreal moments of my career was acting in front of Notre Dame with a mime. "

" I understudied Colm Feore quite a bit in '85 and '86 - 'Persephone' and 'The Boys from Syracuse,' too - and that was great, great training for me. He was and he is an amazing theatre actor. "

" Shelter dogs should be adopted into loving homes, not used in cruel experiments. That's why I support the Cruelty Free International global dog campaign. "

" I have accomplished a lot, but it didn't happen overnight for me. I was 35 when I got the show, and had been working professionally for 15 years. It would be a lot weirder if I were in my early 20s and stumbled into it. "

" It's very strange - several years ago, I was in the running for the 'Young Frankenstein' musical. Kristin Chenoweth was going to do it, but then she backed out because she got 'Pushing Daisies' on TV, and then, the next day, I went in for my final-final audition, and I saw Megan Mullally standing there. "

" When I read the script for Will & Grace in 1998, I knew I was the only guy for the part. "

" It's hard in this business to get the opportunities to show off range. "

" With these scripts and these writers, so much of it is done for me. Because we don't just throw words around: we make sure the audience understands. "

" That's an amazing feeling, to walk onstage, and you're not thinking about anything, you're not thinking about your lines or what you're supposed to do - your body, your brain knows, so there's freedom. There's not fear, there's not nerves. "

" Tom Cavanagh is fantastic. "

" Unfortunately, with men's health, we don't talk about it enough, and prostate cancer gets lost in the conversation. "

" If you can last long enough, in success, you have to get really creative and come up with new stuff. "

" I have to challenge the audience. "

" When I was 16, I'd ping pong between AC/DC and Barry Manilow without any sense of irony. "

" I always get a little uppity when I hear the phrase 'TV actor.' It's like saying you're a magazine reporter. I was in the theater for ten years before I ever had a TV audition. "

" I'm an actor. I can't afford to have a type. I love to mix it up. "

" I love everybody at TNT, and they were totally behind 'Trust Me.' I totally loved that show. I feel like it should have had more life. "

" Particularly in television, we can stereotype ourselves. You realize that we all have a lot of voices in our head. We have angry voices, we have voices of doubt, and we have moments of strength. "

" I think most actors go into the business thinking, 'I can play everything. Why can't I play a black woman? Just give me a chance.' Then you grow up and realize it's probably better that they cast an actual black woman. "

" I'm doing a very funny show in which we talk about issues. I speak at Aids charities and things. It's great to do something fun with our days and yet we're told we're doing something important. "

" As a television actor, there's a power you're given to use your image to do something valuable. As a parent, these messages are particularly important to me. "