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" I secretly had this name 'Nancy and Beth' come into my mind, and I thought, 'Oh my God, that's such a funny, interesting, weird name for a band.' "

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" I had been watching the Emmys since I was probably 5 years old. Those shows, when you're a kid, it all seems like such a big, big deal, and only special certain people would win one of these big things like a Tony or an Emmy or an Oscar. "

" Isn't that sort of what happened with gay marriage? Right before gay marriage was legalized, everybody was just losing their minds and, like, the worst possible things were happening, and it was just all like it couldn't get any worse, and then it suddenly got a lot better. "

" I think a lot of actors, maybe who have been on a hit show and been lucky enough to get successful, might say 'no' more than I do. And maybe that's good, maybe that's smart. I don't know. "

" I always hear some couples can't work together, and I don't get that. We have the most fun when we're working together. "

" In real life, there's nobody more out than Sean. It was just in the press that he didn't want to say one way or another. I think he just felt it was nobody's business, but I feel like he came to it in his own time. "

" Woody Harrelson played a long-term love interest of Debra Messing's; I think it was for a whole season. They almost cast Nick in that part. They almost had given to him. But at the eleventh hour, Jim Burrows put in a call to Woody, and he said he would do it. "

" Nick's just from this very Norman Rockwell-ish family. They're very 'American Gothic,' and his parents are so kind, and they're not brash people; they're very soft spoken, salt of the earth. "

" I can understand everybody associates me with Karen, but beyond that, I think after time passes and a few years go by, that sort of becomes a non-issue. That character is far - I mean really, all the characters I've played are pretty far away from what I'm really like. "

" I love creating new characters that are whatever they are. "

" I've done three Broadway musicals and tons of concerts and all kinds of things, but nobody knows that except the people in New York. "

" I think theater is more about living and breathing, versus TV, which can vary. "

" Sean is so funny. One time he went to Ireland for two weeks with his mother, and Ireland is so beautiful, and he got back; we were like, 'How was it?' and he was like, 'Ugh I was so bored.' "

" I certainly have gay friends, but I don't remember thinking, 'Oh my God, I have this friend, and they're gay, and that's so cool.' I mean, I was very naive until I got to a certain age. "

" People get up and say, 'I didn't prepare a speech because I didn't think I would win.' Well, that's dumb. "

" Speaking theoretically, in a completely made-up world where 'Will & Grace' is coming back to NBC for 10 episodes - just in that made-up world - it couldn't be a better time. I think more so now than even when we started! And who would have ever - I mean, it's heinous that it's because Donald Trump is the president-elect. "

" Multi-camera's fun because you have the immediacy of the audience and just being able to tell the story more or less straight through. The thing I like about single-camera is that you have the luxury of shooting a lot of different options. "

" We have a two-week rule. We're never apart for more two weeks. Just not being separated for Jurassic periods of time seems to help. And no children probably helps a lot. "

" During 'Will & Grace,' we had so many things we had to go to where you get all dolled up. It's like pulling teeth for me. "

" I feel like Nick and I have the best relationship and the best marriage. "

" I love Chicago - absolutely love Chicago. I mean, I'd much rather go to Chicago and do a play or a musical than New York, honestly. Because just probably for reasons that are obvious to you. It's just a little bit - it's a nicer, easier city. "

" People find it confusing I'm in a band, even though music was my main thing before acting. "

" Why can't I ever play a nice, normal, salt-of-the-earth type? Is there something I should know? It's fun to play villains and character roles, of course - but I'm sure it's also fun to be a really big star and play the lead in everything, where all you have to do is show up and not blink. "

" I lived in Chicago in the early '80s and did a ton of theater, and then Nick lived there in the '90s and did a ton of theater. Then we both moved to L.A. and did a ton of television. "

" We're both big Glen Campbell fans - it's one of the things that united us in eternal love. "

" A lot of young people think it all comes to a screeching halt once you're 32. But it really doesn't. "

" I kind of connected the dots, like, 'Oh, we're just saying stuff. We're just saying things that make sense, so let's just say them like you say them in real life.' It was my first and one of my only acting lessons 'cause I never really studied acting. "

" Karen is like RuPaul - she's a character. It never occurred to me until now, but she is! "

" Nick can get up on stage and just wing it, whereas I would have to be taken to a mental institution. "

" We had a gay marriage on 'Will & Grace' in 2000, 2001. And I was like, 'Gay marriage?' I mean, it was just really early. "

" I don't know other couples that work together a fraction as much as Nick and I do. We met in a play, and we've done TV and movies, and we just did 'Annapurna,' our off-Broadway show, and we've done theater together several times, so it's just a little bit of everything. "