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" If you get very fine, accurate, and inexpensive control over your genome, you can fundamentally change the kind of organism you are. You are extending human capacity. "

George M. Church

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" What dinosaur traits are missing from an ostrich? The ostrich has a toothless beak, but there are mutations that cause teeth and claws to come back to their mouth and limbs. You need to replace the feathers with scales, but there are no feathers on their legs and feet, so you just need to make its whole body like its legs are. "

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" The first thing you have to do is to sequence the Neanderthal genome, and that has actually been done. The next step would be to chop this genome up into, say, 10,000 chunks and then... assemble all the chunks in a human stem cell, which would enable you to finally create a Neanderthal clone. "

" It sounds a little bit too arrogant, but I think I certainly have a working model for how I conduct my life, and it may or may not be a correct worldview. "

" Genomics is a new idea. Like the PC, it's not obvious at first that anyone would want one. It's like, 'Hey, we've already got one genome, why do we need more?' "

George M. Church

Why

" There's a lot of faith expressed by scientists about science. It's kind of an act of faith that science is a good thing. We don't know that for sure. We may not know that millions of years from now. "

" Most people are excited about themselves. Personal genome will deliver for inexpensively something about science to which you can relate. Just like computers are becoming something to which you can relate. It should be even easier to relate to your own biology, and I hope that will be one of the ways we get broader literacy in science. "

" The goal of getting your genome done is not to tell you what you will die from, but it's how to learn how to take action to prevent disease. "

" I will make the argument that we are poorly adapted to our current environment. I mean, we did not evolve to sit all day and be exposed to giant amounts of really tasty food. "

" It's all too easy to dismiss the future. People confuse what's impossible today with what's impossible tomorrow. "

" I always loved computers - it's something inside you. "

" Every cell in our body, whether it's a bacterial cell or a human cell, has a genome. You can extract that genome - it's kind of like a linear tape - and you can read it by a variety of methods. Similarly, like a string of letters that you can read, you can also change it. You can write, you can edit it, and then you can put it back in the cell. "

" I think my original inspiration came from just natural curiosity about science and math and biology. In particular, I would say that, as I matured, it became more a feeling of trying to avoid the waste that occurs in the world where we have 6.5 billion minds. If you're a computer scientist, you can think of them as supercomputers. "

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" Neanderthals might think differently than we do. They could even be more intelligent than us. When the time comes to deal with an epidemic or getting off the planet, it's conceivable that their way of thinking could be beneficial. "

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" Reversal is something that has been demonstrated in a number of different animals in a number of different ways. I think that's going to translate into larger animals and humans. We won't know until we try. But we are trying 65 different genes in different combinations to see if we can reproduce the aging reversal that we've seen in small animals. "