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" There's a lot of faith expressed by scientists about science. It's kind of an act of faith that science is a good thing. We don't know that for sure. We may not know that millions of years from now. "

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" What I really wanted was for everybody to have their genome and, ideally, everybody to share their genome, and for that, we needed to bring the price way down. "

George M. Church

Down

Genome

" Reversal of ageing is high on my list of things to do, and not just because I'm getting old. "

" The best way to predict the future is to change it. "

" At some point, someone will come up with an airtight argument as to why they should have a cloned child. At that point, cloning will be acceptable. "

" Reversal is something that has been demonstrated in a number of different animals in a number of different ways. I think that's going to translate into larger animals and humans. We won't know until we try. But we are trying 65 different genes in different combinations to see if we can reproduce the aging reversal that we've seen in small animals. "

" Very often, as I wander through life, I'll get that old feeling that I've come back from the future, and I'm living in the past. And it's a really horrible feeling. "

" We have the ability to completely change our environment to go... to take on... to inherit, in a certain sense, things far beyond our DNA, and that's inheritable. And we can see evolution in action as our ideas evolve and undergo a kind of Darwinian selection not at the DNA level. And we can go off into space. "

" As part of our dedication to safety engineering in biology, we're trying to get better at creating physically contained test systems to develop something that eventually will be so biologically contained that we won't need physical containment anymore. "

" I like to keep the median age in my lab low because they will indulge me in my dreams. They don't yet think things are impossible. "

George M. Church

Will

Think

" I'll drop something for a while, a year or maybe several years, and then pick it up again. I think that's the way successful innovators work. They keep juggling ideas, keeping them in the air, in the back of their mind, to inspire them or enable new recombinations. "

" Your genetics is not your destiny. "

" How do you get things out of your head, out of your lab, and into the world? If you're not part of the economic community, there's a chance... you'll fall behind. "

" If you get a personal genome, you should be able to get personal cell lines, stem cell derived from your adult tissues, that allow you to bring together synthetic biology and the sequencing so that you can repair parts of your body as you age or repair things that were inherited disorders. "

" You can make pigs that are essentially much closer to being universal donors. If it works, their organs will be going into people like you and me. "

George M. Church

Going

" Science has very definite faith components, and most religions don't stick to faith. They venture out into making predictions about our physical world. They don't just say there's something that is completely unconnected to us. They say actually it affects a lot. And when they do that, they merge. "

" There are a few genetic traits that make people feel sorry for you, and there are some, like narcolepsy, at which people take personal offense unless you tell them in advance. "

" It's all too easy to dismiss the future. People confuse what's impossible today with what's impossible tomorrow. "

" What dinosaur traits are missing from an ostrich? The ostrich has a toothless beak, but there are mutations that cause teeth and claws to come back to their mouth and limbs. You need to replace the feathers with scales, but there are no feathers on their legs and feet, so you just need to make its whole body like its legs are. "

" I always loved computers - it's something inside you. "

" I like talking and walking. It's more productive than doing just one. "

George M. Church

Walking

Talking

" I'm pathologically calm. "

George M. Church

Calm

" The goal of reanimation research is not to make perfect living copies of extinct organisms, nor is it meant to be a one-off stunt in a laboratory or zoo. Reanimation is about leveraging the best of ancient and synthetic DNA. "

" I'm a champion for personal differences. I have no sympathy for drug companies that can't figure out how to make personalized medicine. We could generalize that to 'All society should be much more personalized.' "

" We have lots of Neanderthal parts around the lab. We are creating Neanderthal cells. Let's say someone has a healthy, normal Neanderthal baby. Well, then, everyone will want to have a Neanderthal kid. Were they superstrong or supersmart? Who knows? But there's one way to find out. "

" People think it's great to be ahead of your time, but it can actually be quite painful. "

" Every cell in our body, whether it's a bacterial cell or a human cell, has a genome. You can extract that genome - it's kind of like a linear tape - and you can read it by a variety of methods. Similarly, like a string of letters that you can read, you can also change it. You can write, you can edit it, and then you can put it back in the cell. "

" Anytime you see somebody keeping a secret, that's symptomatic that something's wrong with the society around them. That means there's discrimination or worse. "

" Aside from bringing back extinct species, reanimation could help living ones by restoring lost genetic diversity. The Tasmanian devil (aka Sarcophilus harrisii) is so inbred at this point that most species members can exchange tumor cells without rejection. "

" Most groups patent ways of using genetic discoveries as part of non-obvious diagnostic and therapeutic protocols and slightly or greatly altered genes. "

" Genomics is a new idea. Like the PC, it's not obvious at first that anyone would want one. It's like, 'Hey, we've already got one genome, why do we need more?' "

George M. Church

Why