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" Neanderthals might think differently than we do. They could even be more intelligent than us. When the time comes to deal with an epidemic or getting off the planet, it's conceivable that their way of thinking could be beneficial. "

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" What I really wanted was for everybody to have their genome and, ideally, everybody to share their genome, and for that, we needed to bring the price way down. "

George M. Church

Down

Genome

" Reversal is something that has been demonstrated in a number of different animals in a number of different ways. I think that's going to translate into larger animals and humans. We won't know until we try. But we are trying 65 different genes in different combinations to see if we can reproduce the aging reversal that we've seen in small animals. "

" We have the ability to completely change our environment to go... to take on... to inherit, in a certain sense, things far beyond our DNA, and that's inheritable. And we can see evolution in action as our ideas evolve and undergo a kind of Darwinian selection not at the DNA level. And we can go off into space. "

" Reversal of ageing is high on my list of things to do, and not just because I'm getting old. "

" If we go into space, we need enhancements that handle radiation and osteoporosis... or else we're dead. So what seems like an enhancement in one generation becomes life and death in another generation. "

" When something like personal genomics or synthetic biology suddenly appears - it seems to suddenly appear - we might have been working on it for 30 years, but it seems to come out of nowhere. Then you need strategies for engaging a lot of people and thinking about where it will be going in the next few months or few years. "

" Terrorism is not a public health threat, relative to cancer and heart disease and malaria and so forth. "

" People think it's great to be ahead of your time, but it can actually be quite painful. "

" Our ancestors didn't need any genetic enhancements to be able to sit for twelve hours a day and eat fatty, sugary foods, but we need enhancements that handle that altered environment. "

" If you get very fine, accurate, and inexpensive control over your genome, you can fundamentally change the kind of organism you are. You are extending human capacity. "

" What dinosaur traits are missing from an ostrich? The ostrich has a toothless beak, but there are mutations that cause teeth and claws to come back to their mouth and limbs. You need to replace the feathers with scales, but there are no feathers on their legs and feet, so you just need to make its whole body like its legs are. "

" I like to keep the median age in my lab low because they will indulge me in my dreams. They don't yet think things are impossible. "

George M. Church

Will

Think

" Anytime you see somebody keeping a secret, that's symptomatic that something's wrong with the society around them. That means there's discrimination or worse. "

" I will make the argument that we are poorly adapted to our current environment. I mean, we did not evolve to sit all day and be exposed to giant amounts of really tasty food. "

" We have a love affair with the idea of the 'natural,' even though we, as a species, are about as unnatural as you can imagine. "

" It sounds a little bit too arrogant, but I think I certainly have a working model for how I conduct my life, and it may or may not be a correct worldview. "

" I like talking and walking. It's more productive than doing just one. "

George M. Church

Walking

Talking

" If we could take one of my skin cells and turn it into an embryo-like cell and turn it back into a skin cell, it has reset almost all of the developmental indications of age. "

" As part of our dedication to safety engineering in biology, we're trying to get better at creating physically contained test systems to develop something that eventually will be so biologically contained that we won't need physical containment anymore. "

" I think something very simple that everybody can do is they can participate in medical research as subjects. Personal genome project, for example, will take on as many subjects as we can find. "

" Genomics is a new idea. Like the PC, it's not obvious at first that anyone would want one. It's like, 'Hey, we've already got one genome, why do we need more?' "

George M. Church

Why

" Every cell in our body, whether it's a bacterial cell or a human cell, has a genome. You can extract that genome - it's kind of like a linear tape - and you can read it by a variety of methods. Similarly, like a string of letters that you can read, you can also change it. You can write, you can edit it, and then you can put it back in the cell. "

" Making new petroleum should be as simple and straightforward as brewing beer. "

" Science has very definite faith components, and most religions don't stick to faith. They venture out into making predictions about our physical world. They don't just say there's something that is completely unconnected to us. They say actually it affects a lot. And when they do that, they merge. "

" The one thing that is bad for society is low diversity. If you become a monoculture, you are at great risk of perishing. Therefore, the recreation of Neanderthals would be mainly a question of societal risk avoidance. "

" You should have personalized genomics, personalized physiology, personalized medicine, where each person's different, and each body is an integrated whole. "

" Trees are essentially growing chairs. There are lots of primates that sit and sleep in them. "

" I don't think it is about stalling or curing: it's about reversing. Curing gives you the impression of immortality. Stalling gives you the impression that you'll be 85 forever, which is not great. "

" It's all too easy to dismiss the future. People confuse what's impossible today with what's impossible tomorrow. "

" If we can come up with a way of backing up my brain into another that I have in my back-pack, we'll do it. People talk themselves out of things very easily. Things that they think are a million years away, or never, are actually four years away. "