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" It doesn't rain at all in California. Once a month, a man drives through spraying Evian. "

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" Directing is the best job going. I don't understand why everybody doesn't want to direct. It's an absolutely fascinating combination of skills required and puzzles set on every level - emotional and practical and technical. It calls up on such a wide variety of skills. I find it completely absorbing. I just love the whole process. "

" I admit I can't shake the idea that there is virtue in suffering, that there is a sort of psychic economy, whereby if you embrace success, happiness and comfort, these things have to be paid for. "

" One great benefit of not being on TV every week is that people will be a lot less interested in what I have in my supermarket basket. I could even un-tint my car windows - or at least opt for a lighter shade. "

" I think actors are attracted to the idea of other identities and concealing themselves behind some other identity. "

" Lots of people would say House doesn't have any charm at all. I would disagree, though: I find him immensely charming and endlessly entertaining. He has a sort of grace and a wit about him, and ultimately, I think he is on the side of the angels. "

" I have been instrumental in banning bottled water on the set. It hasn't gone that well with the crew... so I replaced it with tequila. "

" To be a head boy, you have to be very clever, you have to be a scholar, and I was never a scholar in any shape or form. "

" I have my moments. Ever since I was a boy, I never was someone who was at ease with happiness. Too often I embrace introspection and self-doubt. I wish I could embrace the good things. "

" To be able to pretend to be something that I'm frankly not is very liberating and exciting. "

" Celebrity is absolutely preposterous. Entertainment seems to be inflating. It used to be the punctuation to your life, a film or a novel or a play, a way of celebrating a good week or month. Now it feels as if it's all punctuation. "

" Unhappiness is an unfinished state; happy people don't need our help. "

" I really do believe the camera steals the soul. But that may be because I'm worried about my soul. I don't have much of a soul to begin with; I can't afford to lose much. "

" It alarms me to think of all that I have read and how little of it has stayed with me. "

" One of the principal goals in my life has been to avoid embarrassing my children by doing the job I do. I hope I've managed to do that, and I hope that, with the job I'm in now, they are, if not proud, at least unembarrassed by it. I must say, my three are most agreeable children, who do nothing but delight me. "

" I've never been clever with money. I will buy anything at the top of the market. "

" I think pain is a very - it's an extremely hard thing to empathize moment to moment. And you often don't remember your own pain, you know, that moment that you broke a limb or you burned yourself or, I think, this is a common thing that women talk about with childbirth, that the memory of the pain is hard to summon up and relive, thankfully. "

" I get anxious about a lot of things, that's the trouble. I get anxious about everything. I just can't stop thinking about things all the time. And here's the really destructive part - it's always retrospective. I waste time thinking of what I should have said or done. "

" I do actually like Los Angeles. Partly because I was told I wouldn't. "

" Riding my motorcycle around L.A. is like my own video game. But unlike many folks at the wheel, I am occupied with getting where I'm going and keeping myself safe. Most people are applying makeup, texting, and checking out the beauty in the next car. "

" I don't really understand why everybody doesn't want to direct. It's an absolutely fascinating combination of skills required and puzzles set on every possible level, emotional and practical and technical. It calls upon such a wide variety of skills. I find it completely absorbing. "

" In film, because you know where the ending is, characters can change, but in television, you substitute revelation for change, and that can be hard to pull off. "

" I feel when acting, I am sometimes overly self-conscious; I think, 'Going, no, don't, put your eyebrow back where it was and, you know, turn to the left.' You know, I'm sort of very consciously adopting this character. But with music, I don't know. I found it was a question of just closing my eyes and just sort of letting things come out. "

" I didn't realize House would be the central character, more the bitter comic relief appearing occasionally. I relish his wounded nature - the lameness, the scarred Byronic hero. "

" Driving a motorcycle is like flying. All your senses are alive. When I ride through Beverly Hills in the early morning, and all the sprinklers have turned off, the scents that wash over me are just heavenly. Being House is like flying, too. You're free of the gravity of what people think. "

" I think of House as a deeply moral character, though some would no doubt argue with me. He does not judge. Beyond his normal tetchiness, there were no more than a half-dozen moments of actual condemnation from him. He understood lies and also why you lied, and there was an absolution there that is very, very appealing. "

" The first big stars, Bessie Smith, Ma Rainey, you know, these were gigantic stars. I even wonder sometimes whether all music actually comes from women, whether the first glimmering of music is a mother soothing a baby. "

" Ideas are 10 a penny. It's the execution that's the hard thing to do. House is standing up against a tide of sentiment and emotionalism over reason that threatens to engulf this world. When you think about it, a rationalist, a man of science and reason, is in a pretty lonely position. "

" I don't have a single complete show or movie or anything else that I could look at and say, 'Nailed that one.' But endless dissatisfaction is, I suppose, what gets us out of bed in the morning. "

" As a real person, he wouldn't last a minute, would he? But drama is about imperfection. And we've moved away from the aspirational hero. We got tired of it, it was dull. If I was House's friend, I would hate it. How he so resolutely refuses to be happy or take the kind-hearted road. But we don't always like morally good people, do we? "

" I grew up with an impatience with the anti-scientific. So I'm a bit miffed with our current love affair with all things Eastern. If I sneeze on the set, 40 people hand me echinacea. But I'd no sooner take that than eat a pencil. Maybe that's why I took up boxing. It's my response to men in white pajamas feeling each other's chi. "