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" My heart beats in three-quarter time. "

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" The brain is a complex biological organ possessing immense computational capability: it constructs our sensory experience, regulates our thoughts and emotions, and controls our actions. "

" The problem of psychoanalysis is not the body of theory that Freud left behind, but the fact that it never became a medical science. It never tried to test its ideas. "

" I like problems at the borders of disciplines. One of the reasons that neurobiology of learning and memory appeal to me so much was that I liked the idea of bringing biology and psychology together. "

" I was born in Vienna on November 7, 1929, eleven years after the multiethnic Austro-Hungarian Empire fell apart following its defeat in World War I. "

" It may act as an ancillary factor, but by itself, the mutation in tau doesn't give you Alzheimer's disease. This is not to say the tau is not very important. It may be important in propagating the disorder from one cell to another. But as a causal mechanism, the evidence is strongest for beta amyloid abnormalities. "

" There was little in my early life to indicate that an interest in biology would become the passion of my academic career. In fact, there was little to suggest I would have an academic career. "

" I would not necessarily say that scientists and artists need to collaborate with one another, but it would be helpful for them to talk to one another to, perhaps, give rise to specific ideas that may or may not be carried out together. "

" Carl von Rokitansky is one of the founders of scientific medicine and systematized it, looking at what the clinical symptoms mean. The medicine we practice today, which is infinitely more sophisticated, is Rokitansky's medicine. "

" Life is sort of a circle. You come back to a lot of the interests that you had early in life. "

" In art, as in science, reductionism does not trivialize our perception - of color, light, and perspective - but allows us to see each of these components in a new way. "

" You could double the number of synaptic connections in a very simple neurocircuit as a result of experience and learning. The reason for that was that long-term memory alters the expression of genes in nerve cells, which is the cause of the growth of new synaptic connections. "

" If you read any of my books, they tend to have a strong historical perspective. "

" I was interested in the nature of human mental processes, which is what got me interested in psychoanalysis. And it became clear to me after a while that mental processes come from the brain, and in order to understand them, you need to be a biologist of the brain. "

" In order to produce learned fear, you take a neutral stimulus like a tone, and you pair it with an electrical shock. Tone, shock. Tone, shock. So the animal learns that the tone is bad news. But you can also do the opposite - shock it at other times, but never when the tone comes on. "

" One can, in principle, outline sort of a set of neural circuits that are critically involved and even identify disorders that affect different components of that neural circuit and see what happens if you knock out, for example, inability to recognize faces, how it affects your response to portraiture. "

" One of the wonderful things about Internet is it's like a salon. It brings people together from different intellectual walks of life. "

" The problem for many people is that we cannot point to the underlying biological bases of most psychiatric disorders. In fact, we are nowhere near understanding them as well as we understand disorders of the liver or the heart. "

" Memory has always fascinated me. Think of it. You can recall at will your first day in high school, your first date, your first love. "

" If you have a lesion in the hippocampus in both sides, you have short term memory, but you can convert that short term memory into long term memory. "

" I found working in the lab is so completely different than reading a textbook about it. You know, you're planning strategies; you're working with your own hands. There's essential satisfaction in running experiments. "

" When I was a medical student in the 1950s, we practically never spoke about Alzheimer's disease. And why is that so? And that is because people didn't live long enough to have Alzheimer's disease. "

" I had many moments of disappointment, despondency, and exhaustion, but I always found that by reading the literature and showing up at my lab looking at the data as they emerged day by day and discussing them with my students and postdoctoral fellows, I would gain a notion of what to do next. "

" As you know, in most areas of science, there are long periods of beginning before we really make progress. "

" Long-term memory involves enduring changes that result from the growth of new synaptic connections. "

" I was reluctant to be critical of the United States because I thought the United States could do no wrong; that the government could not lie to its people. "

" Psychoanalysis has a degree of unreliability about it. You will never know whether you've found the truth. You may find a subjective truth, but you don't know. "

" Ever since the Enlightenment, people thought that we were living in a rational universe. They thought that God was a mathematician and that the function of the scientist was to figure out the mathematical rules whereby the universe was created. "

" Rather than studying the most complex form of memory in a very complicated animal, we had to take the most simple form - an implicit form of memory - in a very simple animal. So I began to look around for very simple animals. And I focused in on the marine snail Aplysia. "

" What the Ellison Foundation and I are hoping to encourage is a more holistic approach to psychiatry, in which psychotherapy is put on as rigorous a level as psychopharmacology. "

" My parents were not born in Vienna, but they had spent much of their lives there, having each come to the city at the beginning of World War I when they were still very young. "