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" Psychoanalysis has a degree of unreliability about it. You will never know whether you've found the truth. You may find a subjective truth, but you don't know. "
Eric Kandel
Find
Truth
Never
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" You learn emotional experiences as much as you learn cognitive experiences, except that they are more unconscious. Sometimes one represses the cognitive component of it, but it's often more difficult to repress the emotional component. "
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" My parents genuinely loved Vienna, and in later years I learned from them why the city exerted a powerful hold on them and other Jews. My parents loved the dialect of Vienna, its cultural sophistication, and artistic values. "
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" My heart beats in three-quarter time. "
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" I was interested in the nature of human mental processes, which is what got me interested in psychoanalysis. And it became clear to me after a while that mental processes come from the brain, and in order to understand them, you need to be a biologist of the brain. "
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" In art, as in science, reductionism does not trivialize our perception - of color, light, and perspective - but allows us to see each of these components in a new way. "
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" I like problems at the borders of disciplines. One of the reasons that neurobiology of learning and memory appeal to me so much was that I liked the idea of bringing biology and psychology together. "
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" The biology of mind bridges the sciences - concerned with the natural world - and the humanities - concerned with the meaning of human experience. "
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" Memory has always fascinated me. Think of it. You can recall at will your first day in high school, your first date, your first love. "
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" As you know, in most areas of science, there are long periods of beginning before we really make progress. "
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Long
Science
Progress
" The problem of psychoanalysis is not the body of theory that Freud left behind, but the fact that it never became a medical science. It never tried to test its ideas. "
Eric Kandel
Ideas
Science
Body
" I have a philosophy that has guided me throughout all of my scientific career, and that is, I think of myself as a fairly thoughtful person. I don't go into projects impetuously, and I try to select important problems. "
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Me
Think
Myself
" You could double the number of synaptic connections in a very simple neurocircuit as a result of experience and learning. The reason for that was that long-term memory alters the expression of genes in nerve cells, which is the cause of the growth of new synaptic connections. "
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" I've been collecting art for much of my adult life. I started around 1960. And my wife and I really enjoy art a great deal. We don't have a lot of money, so we have works on paper, but we enjoy them a great deal. "
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Enjoy
Wife
Money
" A brain scan may reveal the neural signs of anxiety, but a Kokoschka painting, or a Schiele self-portrait, reveals what an anxiety state really feels like. Both perspectives are necessary if we are to fully grasp the nature of the mind, yet they are rarely brought together. "
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Painting
Brain
Nature
" What the Ellison Foundation and I are hoping to encourage is a more holistic approach to psychiatry, in which psychotherapy is put on as rigorous a level as psychopharmacology. "
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Encourage
Foundation
Put
" Long-term memory involves enduring changes that result from the growth of new synaptic connections. "
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Changes
Memory
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" It may act as an ancillary factor, but by itself, the mutation in tau doesn't give you Alzheimer's disease. This is not to say the tau is not very important. It may be important in propagating the disorder from one cell to another. But as a causal mechanism, the evidence is strongest for beta amyloid abnormalities. "
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Evidence
You
Say
" One of the ultimate challenges for biology is to understand the brain's processing of unconscious and conscious perception, emotion, and empathy. "
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Empathy
Perception
Brain
" There was little in my early life to indicate that an interest in biology would become the passion of my academic career. In fact, there was little to suggest I would have an academic career. "
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Life
Passion
Biology
" One of the ultimate challenges of biology is to understand how the brain becomes consciously aware of perception, experience and emotion. But it is equally conceivable that the exchange would be useful for the beholders of art, for people who enjoy art, for historians, and for the artists themselves. "
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" I was born in Vienna on November 7, 1929, eleven years after the multiethnic Austro-Hungarian Empire fell apart following its defeat in World War I. "
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World War I
Defeat
World
" My parents were not born in Vienna, but they had spent much of their lives there, having each come to the city at the beginning of World War I when they were still very young. "
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Parents
City
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" Since Socrates and Plato first speculated on the nature of the human mind, serious thinkers through the ages - from Aristotle to Descartes, from Aeschylus to Strindberg and Ingmar Bergman - have thought it wise to understand oneself and one's behavior. "
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Behavior
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" Indeed, artists, particularly modern artists, have intentionally limited the scope and vocabulary of their expression to convey, as Mark Rothko and Ad Reinhardt do, the most essential, even spiritual, ideas of their art. "
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Spiritual
Ideas
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" One can, in principle, outline sort of a set of neural circuits that are critically involved and even identify disorders that affect different components of that neural circuit and see what happens if you knock out, for example, inability to recognize faces, how it affects your response to portraiture. "
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Different
Involved
You
" Nerve cells communicate with one another at specialized points called synapses. And these synapses are plastic - they can be modified by learning. "
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Plastic
Learning
Communicate
" If you have a lesion in the hippocampus in both sides, you have short term memory, but you can convert that short term memory into long term memory. "
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You
Memory
Long
" I would not necessarily say that scientists and artists need to collaborate with one another, but it would be helpful for them to talk to one another to, perhaps, give rise to specific ideas that may or may not be carried out together. "
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Need
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" The brain is a complex biological organ possessing immense computational capability: it constructs our sensory experience, regulates our thoughts and emotions, and controls our actions. "
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Experience
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" The problem for many people is that we cannot point to the underlying biological bases of most psychiatric disorders. In fact, we are nowhere near understanding them as well as we understand disorders of the liver or the heart. "
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Problem
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People