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" Postwar U.S. was the world's leader in science and technology. The investment in science research was staggering. "
Siddhartha Mukherjee
Leader
Science
Technology
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" The gene that enables birds to learn songs can become cancer-causing. There is no normal physiological process that can't be bastardized by the disease. "
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" A strong intuition is much more powerful than a weal test. Normals teach us rules; outliers teach us laws. For every perfect medical experiment, there is a perfect human bias. "
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" I think when we use 'stress', we are often using a kind of dummy word to try to fit many different things into one big category. "
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" Mary Lasker was an entrepreneur; she was a socialite. She was kind of a legendary networker. She became interested in saying, 'Well, you know, if these diseases don't have political support we'll never conquer them.' And she made, really, cancer her special cause. "
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" If something is good, more is not necessarily better. Not always. "
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" There is an enormous amount of options that a physician can provide today, right down from curing patients, treating patients, or providing patients with psychic solace or pain relief. So, in fact, the gamut of medical intervention is enormous. "
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" When you immerse yourself in medicine you realise that hope is not absolute. It's not that simple. "
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" The idea that cancer genes are sitting inside each and every one of our chromosomes, just waiting to be corrupted or inactivated and thereby unleashing cancer, is, of course, one of the seminal ideas of oncology. "
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" The trick to my writing, it turned out, was doing so exclusively in bed. The minute I even dared to discipline myself and write at the desk, I produced mounds of nonsense. Yet, sitting in bed, I wrote easily, effortlessly, fluidly. I became the master of perfect indiscipline. "
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" What does it mean to be an oncologist? It means that you get to sit in at a moment of another person's life that is so hyper-acute, and not just because they're medically ill. It's also a moment of hope and expectation and concern. "
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" Most discoveries even today are a combination of serendipity and of searching. "
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" I could write a thesis on the physiology of vision. But I had no way to look through the fabric of confabulation spun by a man with severe lung disease who was prescribed 'home oxygen', but gave a false address out of embarrassment because he had no 'home.' "
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" Robert Sandler is a child who died when he was three years old, and he is a child who was the first child that we know of to be treated with chemotherapy. "
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" One day, I had a patient who was going through chemotherapy who came to me and said, 'I'm going to go on with what I'm doing, but I need you to tell me what it is that I'm fighting.' "
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" Pharmacology is benefited by the prepared mind. You need to know what you are looking for. "
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" There's a rising cancer trend and, as I said, one of the major contributors is the overall ageing of the population - we aren't dying of other things, so we're dying of cancer. "
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Things
Dying
Trend
" Each of us knows a few or several young people whose lives have been devastated by cancer. I don't mean to be nihilistic about it, but it is very much an active killer of people now. "
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" Sidney Farber was a pathologist. He was called a doctor of the dead. He was a pathologist who sort of lived in the basement of the children's hospital in Boston, and he became very interested in childhood leukemia. And Farber began to inject this drug, aminopterin, into young kids, in order to see if he could get a remission. "
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" Why did I write 'The Emperor of All Maladies?' A 56-year-old woman with an abdominal sarcoma, having undergone two remissions and a relapse, asked me to describe what she was battling. By the time I had finished answering her, I realised that I had written 600 pages. "
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" Some cancers are curable, while others are highly incurable. The spectrum is enormous. Metastatic pancreatic cancer is a highly incurable disease, whereas some leukemia forms are very curable. There is a big difference between one form and another. "
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" I wanted to explore cancer not just biologically, but metaphorically. The idea that tuberculosis in the 19th century possessed the same kind of frightening and decaying quality was very interesting to me, and it seemed that one could explore the idea that every age defined its own illness. "
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" Probably the most important reason we are seeing more cancers than before is because the population is ageing overall. And cancer is an age-related disease. "
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" I am a scientist and I am a physician. So I write papers. "
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" Because I work on leukemia, the image of cancer I carry in my mind is that of blood. I imagine that doctors who work on breast cancer or pancreatic cancer have very different visualizations. "
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Blood
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" There's a phrase in Shakespeare: he refers to it as the 'hidden imposthume', and this idea of a hidden swelling is seminal to cancer. But even in more contemporary writing it's called 'the big C'. "
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" I think the way we think about cancer, the way we treat cancer, has dramatically changed in the last century. There is an enormous amount of options that a physician can provide today, right down from curing patients, treating patients or providing patients with psychic solace or pain relief. "
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" Unlike other diseases, the vulnerability to cancer lies in ourselves. We always thought of disease as exogenous, but research into cancer has turned that idea on its head - as long as we live, grow, age, there will be cancer. "
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" I believe the biggest breakthroughs on cancer could come from brilliant researchers based in India. "
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" Cell culture is a little like gardening. You sit and you look at cells, and then you see something and say, 'You know, that doesn't look right'. "
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" A breast cancer might turn out to have a close resemblance to a gastric cancer. And this kind of reorganization of cancer in terms of its internal genetic anatomy has really changed the way we treat and approach cancer in general. "
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