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" There was no joke I could make that was too offensive. I can actually remember at least one time where my mother told me something that, I was like, 'whoa!' "

Seth MacFarlane

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" The Simpsons are ugly-looking, and they should be. That's what works. That's one of the things that's funny. "

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" At one point, I was hell-bent on being a Disney animator, and sort of got over that in college and wanted to do my own stuff. You know, towards the end of college I had actually planned to go to the Boston Conservatory of Music for musical theater. "

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" The quest for Tommy Lee Jones' laugh begins now. "

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" The resistance to science is idiotic. "

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" The way Disney characters move, they're very kind of slow and fluid and flowing; one pose kind of eases into the next. If you look at a show like 'The Simpsons' and subsequently a show like 'Family Guy' - the characters will jerk from pose to pose a lot, a bit more snappy. Which sort of goes along with the writing tone of the show. "

Seth MacFarlane

" I'll tell you what I think is not okay. Have you ever seen that show on MSNBC, 'Lockup?' It's a reality show that takes place inside a prison. Do the prisoners have to sign release forms? Or do they have to be on it whether they like it or not? "

Seth MacFarlane

" I love the English. My God, they brought us 'Benny Hill,' 'Monty Python,' 'The Office,' Neville Chamberlain. "

Seth MacFarlane

" I always thought it would be funny to have the Parents Television Council write an episode of 'Family Guy' and give them full creative control. Then see how good the episode is. That's something we've actually discussed in the writers' room. We haven't proposed it yet, but if somebody from the PTC reads this, it might be worth discussing. "

Seth MacFarlane

" 'American Dad' is, by its nature, much more political. "

Seth MacFarlane

" If something sticks around long enough that it makes it to seasonal D.V.D. release, I'll watch it. That's how I watched 'The Sopranos'. "

Seth MacFarlane

" I'm one of the few people in Hollywood who actually had a good childhood. "

Seth MacFarlane

" I think at times I read too much of my own press. I wish I was better at taking in how great my life is, but that's surprisingly elusive. I tend to be very hard on myself and insecure about failing no matter what happens. "

Seth MacFarlane

" If I were to do a musical, I think I would rather make a film musical. "

Seth MacFarlane

" If a song is funny and absurd, and it sounds great, it's just going to be that much funnier. And there's no better example of that than 'Monty Python.' "

Seth MacFarlane

" I can't believe I am hosting the Oscars. It's an honor everyone else said no. "

Seth MacFarlane

" I was a film major with a concentration in animation. "

Seth MacFarlane

" The worst thing to happen at the Oscars would be if nothing happened. You want something unscripted, something to riff on, something kinda out there. "

Seth MacFarlane

" I was a big Fred Flintstone fan. "

Seth MacFarlane

" I cannot tell good art from bad art. I have no eye for it. "

Seth MacFarlane

" The trend today is vampires, zombies, angels, all the stuff that puts me right to sleep. It's too bad because it's so much less interesting than the diversity of stories you can tell with science. "

Seth MacFarlane

" I was about two years old when I first started drawing recognizable characters. "

Seth MacFarlane

" The average person has eight different jobs over the course of their lifetime. You get a little antsy doing the same thing. "

Seth MacFarlane

" I'm sure there are close calls that we're not even aware of hundreds of times a year. You cross the street, and if you'd crossed the street two minutes later, you'd have been hit by a car, but you'd never know it. I'm sure that kind of stuff happens all the time. "

Seth MacFarlane

" When you are in a room and your job is to write jokes 10 hours a day, your mind starts going to strange places. "

Seth MacFarlane

" Evolution doesn't care whether you believe in it or not, no more than gravity does. I want to rekindle excitement over what we've achieved as a species with the space program. We can't afford to regress back to the days of superstition. "

Seth MacFarlane

" When 'Family Guy' started, we wanted to make it more like a sitcom. And there was very little music. "

Seth MacFarlane

" Chris Elliott could read the phonebook and he's funny. "

Seth MacFarlane

" The problem with the cable networks is the lack of money, not from personal income but as far as show budget. "

Seth MacFarlane

" Obviously I'm a big fan of 'South Park', but it gets tiring at times when there's so much of it. "

Seth MacFarlane

" We never really tried to shock for shock's sake on 'Family Guy'. If something was horribly offensive and shocking, we would put it in if it was also hysterically funny. "

Seth MacFarlane