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" What I really wanted was for everybody to have their genome and, ideally, everybody to share their genome, and for that, we needed to bring the price way down. "
George M. Church
Share
Down
Genome
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" How do you get things out of your head, out of your lab, and into the world? If you're not part of the economic community, there's a chance... you'll fall behind. "
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" Reversal of ageing is high on my list of things to do, and not just because I'm getting old. "
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" If we could take one of my skin cells and turn it into an embryo-like cell and turn it back into a skin cell, it has reset almost all of the developmental indications of age. "
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" Trees are essentially growing chairs. There are lots of primates that sit and sleep in them. "
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" I'll drop something for a while, a year or maybe several years, and then pick it up again. I think that's the way successful innovators work. They keep juggling ideas, keeping them in the air, in the back of their mind, to inspire them or enable new recombinations. "
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" As part of our dedication to safety engineering in biology, we're trying to get better at creating physically contained test systems to develop something that eventually will be so biologically contained that we won't need physical containment anymore. "
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" I like talking and walking. It's more productive than doing just one. "
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" If society becomes comfortable with cloning and sees value in true human diversity, then the whole Neanderthal creature itself could be cloned by a surrogate mother chimp - or by an extremely adventurous female human. "
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" Anytime you see somebody keeping a secret, that's symptomatic that something's wrong with the society around them. That means there's discrimination or worse. "
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" You should have personalized genomics, personalized physiology, personalized medicine, where each person's different, and each body is an integrated whole. "
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" We know that there is a connection between our feelings and our brain. "
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" I always loved computers - it's something inside you. "
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" The one thing that is bad for society is low diversity. If you become a monoculture, you are at great risk of perishing. Therefore, the recreation of Neanderthals would be mainly a question of societal risk avoidance. "
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" If we go into space, we need enhancements that handle radiation and osteoporosis... or else we're dead. So what seems like an enhancement in one generation becomes life and death in another generation. "
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" Most people are excited about themselves. Personal genome will deliver for inexpensively something about science to which you can relate. Just like computers are becoming something to which you can relate. It should be even easier to relate to your own biology, and I hope that will be one of the ways we get broader literacy in science. "
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" There's a lot of faith expressed by scientists about science. It's kind of an act of faith that science is a good thing. We don't know that for sure. We may not know that millions of years from now. "
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" The rewards for biotechnology are tremendous - to solve disease, eliminate poverty, age gracefully. It sounds so much cooler than Facebook. "
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" The best way to predict the future is to change it. "
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" Why would you not have a robot that looks like Abraham Lincoln? Why would it look like an erector set? Why use a computer with a punchcard, when you could use one with a touch pen on the screen? Why a car, when you could use a jetpack? "
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" I don't think it is about stalling or curing: it's about reversing. Curing gives you the impression of immortality. Stalling gives you the impression that you'll be 85 forever, which is not great. "
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" What dinosaur traits are missing from an ostrich? The ostrich has a toothless beak, but there are mutations that cause teeth and claws to come back to their mouth and limbs. You need to replace the feathers with scales, but there are no feathers on their legs and feet, so you just need to make its whole body like its legs are. "
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" Your genetics is not your destiny. "
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" Clearly, we are a species that is well connected to other species. Whether or not we evolve from them, we are certainly very closely related to them. A series of mutations could change us into all kinds of intermediate species. Whether or not those intermediate species are provably in the past, they could easily be in our future. "
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" I will make the argument that we are poorly adapted to our current environment. I mean, we did not evolve to sit all day and be exposed to giant amounts of really tasty food. "
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" A few dozen changes to the genome of a modern elephant - to give it subcutaneous fat, woolly hair and sebaceous glands - might suffice to create a variation that is functionally similar to the mammoth. Returning this keystone species to the tundras could stave off some effects of warming. "
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" Every cell in our body, whether it's a bacterial cell or a human cell, has a genome. You can extract that genome - it's kind of like a linear tape - and you can read it by a variety of methods. Similarly, like a string of letters that you can read, you can also change it. You can write, you can edit it, and then you can put it back in the cell. "
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" We went from a world where almost nobody knew anything about computers to a world where almost all of us are computer geeks for a huge fraction of our day. And I'd like to see that happen with the digital world of biological molecules, too. "
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" If we can come up with a way of backing up my brain into another that I have in my back-pack, we'll do it. People talk themselves out of things very easily. Things that they think are a million years away, or never, are actually four years away. "
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