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" As long as humans have existed, we have always desired to live longer. Every society, every religion, every culture. Of course, they all failed at dramatic life extension. "

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" If you do an autopsy on an 85-year-old who died of a stroke, you will find five other things that person was about to die from. "

S. Jay Olshansky

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" The only control we have over the duration of our life is to shorten it, and we do that all the time. "

" The field of ageing research is full of characters. We have hucksters claiming that cures for ageing can be bought and sold; prophetic seers, their hands extended for money, warning that immortality is nigh; and would-be Nobelists working methodically in laboratories in search of a pill to slow ageing. "

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" The Faustian trade of the 20th century was, we got 30 years of additional life, but in return we got heart disease, cancer, stroke, Alzheimer's and sensory impairments. The question is: What Faustian trade are we making now, as we go after heart disease, cancer, stroke and Alzheimer's? "

S. Jay Olshansky

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" If you can slow the biological process of aging, even a minor slowdown in the rate at which we age yields improvements in virtually every condition of frailty and disability and mortality that we see at later ages. "

" In Genesis 6:3, it says man can live to be 120, but there is no scientific basis for it. "

" Just because someone looks old doesn't mean he or she is. The skin of some people who spend a lot of time outdoors seems to age very rapidly. Someone can look 80 or 90 and only be 40 to 50. "

" Humans will die like all living things do, but we have the added burden of knowing that we will. "

" Exercise is roughly the only equivalent of a fountain of youth that exists today, and it's free to everyone. "

" Do we really want to continue to push out the envelope of survival only to see other things crop up that we may not like? "

" The fact is that nothing in gerontology even comes close to fulfilling the promise of dramatically extended lifespan, in spite of bold claims to the contrary that by now should sound familiar. "

" As soon as a handful of scientists come up with an intervention shown to influence aging in other species, they begin selling it as an intervention for humans, even though there may not be evidence it works. "

" You can open up a centenarian's brain, and you'll see some areas that look like that of a 50-year-old or of a 110-year-old. You can have variation in the basic process of aging, called senescence, in different parts of the same body. "

" Fixing obesity is going to require a change in our modern relationship with food. I'm hopeful that we begin to see a turnaround in this childhood obesity epidemic. "

" Physical immortality is seductive. The ancient Hindus sought it; the Greek physician Galen from the 2nd Century A.D. and the Arabic philosopher/physician Avicenna from the 11th Century A.D. believed in it. "

" We have grown accustomed to the wonders of clean water, indoor plumbing, laser surgery, genetic engineering, artificial joints, replacement body parts, and the much longer lives that accompany them. Yet we should remember that the vast majority of humans ever born died before the age of 10 from an infectious disease. "

" A lot of people are living in a dream world - they want to deny that aging occurs or believe it doesn't have to occur. They'll hold on to this belief until the moment they die. The reality will eventually hit them. "

" The last thing you ever want to do is extend the period of frailty and disability and make people unhealthy for a longer time period. So lifespan extension in and of itself should not be the goal of medicine, nor should it be the goal of public health, nor should it be the goal of aging science. "

" Once DNA acquires the ability to persist forever, the carriers become disposable. Essentially, our bodies are designed to last long enough to reproduce. "

" A lifetime of low calories has come naturally to the longest-lived people in the world... in the Japanese archipelago of Okinawa. "

" I'm not sure the least educated members of the population are missing out on the advances in medical technology as much as they are adopting harmful behavioral habits that shorten their life. "

" The vast majority of studies say anti-aging supplements don't work. "

" Death is a zero sum game for which there is no cure. "

" People pushing the idea that everyone can live to be 100 are perpetuating a myth that goes all the way back to the Bible. "

" The reason we have cancer and heart disease is the same reason you can't get rid of the wear and tear on your tires on your car: as soon as you use them, you are wearing them away. You can't make eternal tires, and it's the same with the human body. "

" The evolutionary theory of senescence can be stated as follows: while bodies are not designed to fail, neither are they designed for extended operation. "

" I have little doubt that gerontologists will eventually find a way to avoid, or more likely, delay, the unpleasantries of extended life. "

" I don't have a fear of aging or a fear of death. "

" Lifespan extension has never really been a goal of aging science, nor should it. "

" There is no empirical evidence to suggest that ageing in humans has been modified by any means, nor is there evidence that it is even possible to measure biological age. And nothing has been demonstrated to be true when it comes to anti-ageing medicines. "