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" I am myself sometimes, and I do state my opinions, but not in a comedy routine and not in my character. There always has to be some sort of layer to it. "

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" I love 'The Godfather' and 'Casablanca' - great stories, acted well, made well. "

" There are no Hollywood stars speaking out for the elderly. They're forgotten, bewildered, and I don't think it's because people are cruel or don't care. It's because you don't want to think about your own mortality. I think people don't talk about it enough. "

" I lift weights. Then I put them down again. "

" Free speech is one of the most important things to me, but I think it gets confusing when it comes to offense. Because for one, just because you have the right to say anything, it doesn't mean you have to. "

" When I see a headline 'Guess who's going out with who?' I don't guess, and I don't click. "

" Believe it or not, I work out regularly. "

" Comedy is easy for me, but with drama, I don't know... it's still the Holy Grail. "

" You give up a lot being an atheist. "

" I'm a scientist at heart, so I know how important the truth is. However inconvenient, however unattractive, however embarrassing, however shocking, the truth is the truth, and wanting it not to be true doesn't change things. "

" You can laugh at anything. It depends on the joke. "

" When I was growing up, I didn't like cheese. I had to wean myself onto cheese. "

" Luckily, even when people are shouting lies, the truth is undamaged. Science doesn't matter what you believe. "

" I don't believe in ghosts or ESP or elves... or God. But I am spiritual in the sense that I get a lump in my throat when I listen to Vaughan Williams. "

" I didn't know I was poor, growing up, because everyone was in the same boat. I couldn't have bikes. It never really bothered me, but I could have any book. I loved school; I loved learning. Yeah, I never cared for possessions. I still don't, really. "

" I was very protective of my privacy. I didn't want people to write bad things about me that weren't true, because that's just not fair. Fifty percent of everything written about me is wrong. "

" What makes 'Derek' a different kind of sitcom - if it is even a sitcom - is its sincerity. "

" Sometimes being old is used as an insult, which is bizarre because, if you're lucky, that's literally going to happen to you. It's a strange thing to gloat about: being born recently. "

" You should make something. You should bring something into the world that wasn't in the world before. It doesn't matter what it is. It doesn't matter if it's a table or a film or gardening-everyone should create. You should do something, then sit back and say, 'I did that.' "

" I could always take a joke. I could always be the butt of the joke. I could always hand it out. That was just who I was. "

" I'd never tried as hard with anything as I did with 'The Office,' and it was one of the things I'm proud of. I wasn't trying to be famous or a comedian, but this opportunity came along when I was 38 or 39. It came late, and I couldn't have been prouder of it. "

" Science is constantly proved all the time. If we take something like any fiction, any holy book, and destroyed it, in a thousand years' time, that wouldn't come back just as it was. Whereas if we took every science book and every fact and destroyed them all, in a thousand years they'd all be back because all the same tests would be the same result. "

" I don't know what Trump has to do to lose his supporters. It's like a religion. He's a school bully. "

" Humor is to get us over terrible things. "

" I am not a wolf in sheep's clothing, I'm a wolf in wolf's clothing. "

" With Netflix, I browse; I watch documentaries about things I'd never dream of, but I think, 'I might as well.' "

" I don't do karaoke. I don't dance, even at weddings. I'm the grumpy one sitting down drinking wine. "

" When I go to work, I don't want to make depressing, gritty, urban stories that are depressing to watch. I want to give people something to enjoy. When people think I'm a control freak and an ogre - which I am - it's only because I want my work to be accessible and Everyman, in a way. "

" I was never ambitious. I was never ambitious at school. "

" Stupidity without malice isn't horrible; some people can't help it. "

" I'm influenced by those '40s, '50s, and '60s films: things like 'The Apartment' - I was a big fan of Billy Wilder. "