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" Nerve cells communicate with one another at specialized points called synapses. And these synapses are plastic - they can be modified by learning. "
Eric Kandel
Plastic
Learning
Communicate
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" In the 1950s and early 1960s, psychoanalysis swept through the intellectual community, and it was the dominant mode of thinking about the mind. People felt that this was a completely new set of insights into human motivation, and that its therapeutic potential was significant. "
Eric Kandel
Community
People
Mind
" In art, as in science, reductionism does not trivialize our perception - of color, light, and perspective - but allows us to see each of these components in a new way. "
Eric Kandel
Art
Science
Perspective
" Carl von Rokitansky is one of the founders of scientific medicine and systematized it, looking at what the clinical symptoms mean. The medicine we practice today, which is infinitely more sophisticated, is Rokitansky's medicine. "
Eric Kandel
Mean
Looking
Medicine
" Life is sort of a circle. You come back to a lot of the interests that you had early in life. "
Eric Kandel
Come
You
Life
" I was interested in the nature of human mental processes, which is what got me interested in psychoanalysis. And it became clear to me after a while that mental processes come from the brain, and in order to understand them, you need to be a biologist of the brain. "
Eric Kandel
Nature
Me
Need
" I've been around a long time, and I've been interested in memory for a long time. And one of my earlier interests in molecular biology of memory led me to define the switch that converts short term to long term memory. "
Eric Kandel
Time
Long
Long Time
" Rather than studying the most complex form of memory in a very complicated animal, we had to take the most simple form - an implicit form of memory - in a very simple animal. So I began to look around for very simple animals. And I focused in on the marine snail Aplysia. "
Eric Kandel
Look
Simple
Memory
" One can, in principle, outline sort of a set of neural circuits that are critically involved and even identify disorders that affect different components of that neural circuit and see what happens if you knock out, for example, inability to recognize faces, how it affects your response to portraiture. "
Eric Kandel
Different
Involved
You
" I've been collecting art for much of my adult life. I started around 1960. And my wife and I really enjoy art a great deal. We don't have a lot of money, so we have works on paper, but we enjoy them a great deal. "
Eric Kandel
Enjoy
Wife
Money
" The problem for many people is that we cannot point to the underlying biological bases of most psychiatric disorders. In fact, we are nowhere near understanding them as well as we understand disorders of the liver or the heart. "
Eric Kandel
Problem
Understanding
People
" My heart beats in three-quarter time. "
Eric Kandel
Heart
Beats
Time
" I found working in the lab is so completely different than reading a textbook about it. You know, you're planning strategies; you're working with your own hands. There's essential satisfaction in running experiments. "
Eric Kandel
Reading
Know
Own
" What the Ellison Foundation and I are hoping to encourage is a more holistic approach to psychiatry, in which psychotherapy is put on as rigorous a level as psychopharmacology. "
Eric Kandel
Encourage
Foundation
Put
" I was born in Vienna on November 7, 1929, eleven years after the multiethnic Austro-Hungarian Empire fell apart following its defeat in World War I. "
Eric Kandel
World War I
Defeat
World
" Indeed, artists, particularly modern artists, have intentionally limited the scope and vocabulary of their expression to convey, as Mark Rothko and Ad Reinhardt do, the most essential, even spiritual, ideas of their art. "
Eric Kandel
Spiritual
Ideas
Expression
" I would not necessarily say that scientists and artists need to collaborate with one another, but it would be helpful for them to talk to one another to, perhaps, give rise to specific ideas that may or may not be carried out together. "
Eric Kandel
Need
Say
Rise
" Modernism in Vienna brought together science and culture in a new way to create an Age of Insight that emphasized a more complex view of the human mind than had ever existed before. "
Eric Kandel
Mind
Culture
Age
" Early in my career, I was disappointed that psychoanalysis was not becoming more empirical, was not becoming more scientific. It was primarily concerned with individual patients. It wasn't trying to collect data from large groups of people who have been analyzed. "
Eric Kandel
People
Early
Data
" I was reluctant to be critical of the United States because I thought the United States could do no wrong; that the government could not lie to its people. "
Eric Kandel
People
Government
Lie
" One of the ultimate challenges for biology is to understand the brain's processing of unconscious and conscious perception, emotion, and empathy. "
Eric Kandel
Empathy
Perception
Brain
" My parents were not born in Vienna, but they had spent much of their lives there, having each come to the city at the beginning of World War I when they were still very young. "
Eric Kandel
Parents
City
Beginning
" When I was a medical student in the 1950s, we practically never spoke about Alzheimer's disease. And why is that so? And that is because people didn't live long enough to have Alzheimer's disease. "
Eric Kandel
Enough
Long
Live
" You could double the number of synaptic connections in a very simple neurocircuit as a result of experience and learning. The reason for that was that long-term memory alters the expression of genes in nerve cells, which is the cause of the growth of new synaptic connections. "
Eric Kandel
Growth
Experience
Simple
" I like problems at the borders of disciplines. One of the reasons that neurobiology of learning and memory appeal to me so much was that I liked the idea of bringing biology and psychology together. "
Eric Kandel
Memory
Together
Learning
" The brain is a complex biological organ possessing immense computational capability: it constructs our sensory experience, regulates our thoughts and emotions, and controls our actions. "
Eric Kandel
Experience
Thoughts
Emotions
" If you read any of my books, they tend to have a strong historical perspective. "
Eric Kandel
Strong
Perspective
Read
" You learn emotional experiences as much as you learn cognitive experiences, except that they are more unconscious. Sometimes one represses the cognitive component of it, but it's often more difficult to repress the emotional component. "
Eric Kandel
Sometimes
More
Learn
" I went to medical school after having decided to do so somewhere between my junior and senior year at Harvard - very late. I initially wanted to be an intellectual historian. "
Eric Kandel
Intellectual
Late
School
" There was little in my early life to indicate that an interest in biology would become the passion of my academic career. In fact, there was little to suggest I would have an academic career. "
Eric Kandel
Life
Passion
Biology
" As you know, in most areas of science, there are long periods of beginning before we really make progress. "
Eric Kandel
Long
Science
Progress