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" A fundamental premise in cancer therapy is trying to identify how the metabolism of cancer cells differs from normal tissue. When differences are identified, it often paves the way for treatments that will disrupt the cancer's metabolism while sparing normal tissue. "

David Perlmutter

Way

Trying

Normal

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" It may seem draconian, but the best recommendation I can make is to completely avoid grains. "

" Far from being entirely dependent on exogenous food sources of antioxidants, our cells have their own innate ability to generate antioxidants upon demand. "

" This low-fat idea that's been drummed into our heads and bellies is completely off-base and deeply responsible for most of our modern ills. "

" Making changes in the fast food that makes up such a significant part of the American diet, even if the numbers aren't impressive, will have important health up sides. "

" Carbs are devastating for the brain. "

" Parkinson's is described as a progressive idiopathic neurodegenerative disorder, a brain disease that will worsen with time for which no cause has as yet been identified. "

" Even slight elevations in blood sugar have been shown to increase the risk of Alzheimer's disease. "

" Antioxidants are chemicals that break down or neutralize the damaging effects of free radicals - chemicals produced as a byproduct of normal cellular metabolism. "

" As a practicing neurologist, I can tell you first hand that working with Parkinson's patients offers clinical challenges. But from an emotional perspective, this disease can border on overwhelming. "

" The best diet for overall health, and specifically for heart, brain, and cancer risk reduction, is a diet that's aggressively low in carbohydrates with an abundance of healthful fat, and this is the central theme of 'Grain Brain.' "

" The biggest issue by far is that carbohydrates are absolutely at the cornerstone of all of our major degenerative conditions. "

" So-called 'complex carbs' may actually represent a more significant threat to health than simple sugar in that they may not only raise blood sugar, but keep it elevated for a more prolonged period of time. "

David Perlmutter

Simple

Time

" As a practicing neurologist, I place central importance in applying current science to the notion of disease prevention. "

" While the hippocampus itself doesn't store memories, it serves to triage our experiences based upon their survival significance. "

" The story of gluten as it relates to the brain throws a wide net, so much more encompassing than the inflammation of a small section of the small intestine that characterizes celiac disease. "

" Food is medicine. We can actually change our gene expressions with the foods we eat. "

" Shoot for a total of no more than 80 grams of carbs in your daily diet. This means favoring vegetables that grow above ground like kale, broccoli, spinach, and cauliflower as opposed to those that store carbohydrate in the form of starch like potatoes and beets. "

David Perlmutter

Diet

Daily

" In general, the public knowledge base and thus decision-making behaviors are far more influenced by advertisement than with current science. "

" Throughout our lifetimes, we are constantly regenerating new brain cells in the hippocampus, a process called neurogenesis. New stem cells are constantly being born in the hippocampus that ultimately differentiate into fully functional neurons. "

" From the earliest moments of life, children begin to learn the fundamentals of language. The most powerful influence for effective language development are the verbal interactions with caregivers. "

" When we are exposed to a real or perceived threatening situation, powerful things happen in the brain to memorialize aspects of the event, including all manner of associated circumstances like where, when and how it occurred. "

David Perlmutter

Real

Powerful

" Bad things happen. And the human brain is especially adept at making sure that we keep track of these events. This is an adaptive mechanism important for survival. "

" Dementia is our most-feared illness, more than heart disease or cancer. "

" Fat is your friend. The brain thrives on a fat-rich, low-carbohydrate diet. "

" Saturated fat is a fundamental building block for brain cells. It's certainly interesting to consider that one of the richest sources of saturated fat in nature is human breast milk. "

" Children need to be exploring their physical world. They need to be learning the fundamental laws of physics by manipulating objects. "

" Strokes are categorized as either bleeding into the brain or a blockage in blood supply, known as an ischemic stroke. The latter are overwhelmingly more common, compromising about 87 percent of all stroke events. "

David Perlmutter

Blood

Brain

" Memory enhancement self-help programs abound and promise improved memory performance by the utilization of any number of seemingly unique techniques focused on the context of how information is encoded. "

" Most grain foods, whether we're talking about quinoa, amaranth, the very popular grains of the day - the reality is they still are associated with a carbohydrate surge. "

" The food we eat goes beyond its macronutrients of carbohydrates, fat and protein. It's information. It interacts with and instructs our genome with every mouthful, changing genetic expression. "